Stem cell therapeutics: potential in the treatment of inflammatory bowel disease
Swenson E, Theise N. Stem cell therapeutics: potential in the treatment of inflammatory bowel disease. Clinical And Experimental Gastroenterology 2010, 3: 1-10. DOI: 10.2147/ceg.s12187482.Peer-Reviewed Original ResearchInflammatory bowel diseaseAllogeneic hematopoietic transplantationHematopoietic stem cellsTreatment of inflammatory bowel diseaseHematopoietic transplantationPredisposition to inflammatory bowel diseaseHost immune responseMesenchymal stem cellsStem cellsGenetic predisposition to inflammatory bowel diseaseSystemically infused mesenchymal stem cellsFistulas associated with Crohn's diseaseGraft-versus-host diseaseImmune responseHematopoietic stem cell transplantationBowel diseaseAutologous hematopoietic transplantationGraft-versus-hostStem cell transplantationDownregulate host immune responsesRisk of complicationsStem cell therapyStem cell therapy applicationsAutologous hematopoietic reconstitutionBlood cell linesStem cell therapeutics: potential in the treatment of inflammatory bowel disease
Swenson E, Theise N. Stem cell therapeutics: potential in the treatment of inflammatory bowel disease. Clinical And Experimental Gastroenterology 2010, Volume 3: 1-10. PMID: 21694840, PMCID: PMC3108654, DOI: 10.2147/ceg.s6836.Peer-Reviewed Original ResearchInflammatory bowel diseaseAllogeneic hematopoietic transplantationHost immune responseHematopoietic transplantationMesenchymal stem cellsBlood cell linesBowel diseaseImmune responseGenetic predispositionStem cellsLarge clinical trialsAutologous hematopoietic transplantationAutologous hematopoietic reconstitutionHost diseaseCrohn's diseaseMucosal immunityClinical trialsHematopoietic reconstitutionSmall seriesTransplantationGreater riskCell therapyDiseaseDonor cellsBaseline state
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