Nonlinearity of the Inverse Relationship between High-Density Lipoprotein (HDL) Cholesterol and Incident Cardiovascular Risk: Is It Time to Revisit the “HDL Hypothesis”?
Hashem C, Altin S, Guyton J, Boden W. Nonlinearity of the Inverse Relationship between High-Density Lipoprotein (HDL) Cholesterol and Incident Cardiovascular Risk: Is It Time to Revisit the “HDL Hypothesis”? Journal Of Clinical Lipidology 2024 PMID: 39934033, DOI: 10.1016/j.jacl.2024.12.009.Peer-Reviewed Original ResearchLow HDL-CHDL-C levelsHDL-CAssociated with atherosclerotic cardiovascular diseaseRandomized controlled trialsLow levels of high-density lipoprotein cholesterolLow HDL-C levelsLevels of high-density lipoprotein cholesterolIncident cardiovascular riskLevels of HDL-CReduce ASCVD eventsHigh-density lipoprotein cholesterolOptimal risk stratificationHigh-density lipoprotein (HDLStatin-based therapyHDL hypothesisAtherosclerotic cardiovascular diseaseLipoprotein (HDLRisk-enhancing factorsIncident cardiovascular eventsCholesterol guidelinesRisk stratificationCardiovascular eventsLipoprotein cholesterolCardiovascular risk
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