2009
Evolution of Transcriptional Regulatory Circuits in Bacteria
Perez JC, Groisman EA. Evolution of Transcriptional Regulatory Circuits in Bacteria. Cell 2009, 138: 233-244. PMID: 19632175, PMCID: PMC2726713, DOI: 10.1016/j.cell.2009.07.002.Peer-Reviewed Original ResearchConceptsTranscription factorsRegulatory circuitsOrthologous transcription factorsBacterial regulatory circuitsAncestral transcription factorTranscriptional regulatory circuitsDistinct gene setsHorizontal gene transferSpecies-specific genesEukaryotic speciesPromoter structureRelated organismsGene setsRegulatory differencesGene transferGenesCircuit evolutionBacteriaOrganismsRewiringSpeciesDivergenceEvolutionExpressionCues
2008
The PhoQ/PhoP Regulatory Network of Salmonella enterica
Kato A, Groisman EA. The PhoQ/PhoP Regulatory Network of Salmonella enterica. Advances In Experimental Medicine And Biology 2008, 631: 7-21. PMID: 18792679, DOI: 10.1007/978-0-387-78885-2_2.Peer-Reviewed Original ResearchConceptsTwo-component regulatory systemPathogen Salmonella enterica serovar TyphimuriumEnteric pathogen Salmonella enterica serovar TyphimuriumDistinct expression levelsPhoQ/PhoPTwo-component systemSalmonella enterica serovar TyphimuriumBacterial cell surfacePhoQ proteinPhoP proteinResponse regulatorTranscriptional cascadeConnector proteinEnterica serovar TyphimuriumPromoter structureRegulatory networksTranscription factorsSalmonella genesRegulatory architectureSalmonella lifestyleMajor regulatorExpression propertiesCell surfaceModifies expressionRegulatory system