2023
Recruited macrophages elicit atrial fibrillation
Hulsmans M, Schloss M, Lee I, Bapat A, Iwamoto Y, Vinegoni C, Paccalet A, Yamazoe M, Grune J, Pabel S, Momin N, Seung H, Kumowski N, Pulous F, Keller D, Bening C, Green U, Lennerz J, Mitchell R, Lewis A, Casadei B, Iborra-Egea O, Bayes-Genis A, Sossalla S, Ong C, Pierson R, Aster J, Rohde D, Wojtkiewicz G, Weissleder R, Swirski F, Tellides G, Tolis G, Melnitchouk S, Milan D, Ellinor P, Naxerova K, Nahrendorf M. Recruited macrophages elicit atrial fibrillation. Science 2023, 381: 231-239. PMID: 37440641, PMCID: PMC10448807, DOI: 10.1126/science.abq3061.Peer-Reviewed Original ResearchConceptsAtrial fibrillationStromal cellsMitral valve regurgitationHeart failureValve regurgitationInflammatory monocytesMacrophage expansionMonocyte migrationMouse atriaFibrillationHuman atriumAtriumCell-cell interaction analysisSingle-cell transcriptomesMiceCell compositionHypertensionTranscriptome changesImmunotherapySPP1CellsRegurgitationObesityPatientsArrhythmias
2016
Cesarean section in the setting of severe pulmonary hypertension requiring extracorporeal life support
Hara R, Hara S, Ong CS, Schwartz G, Sciortino C, Hibino N. Cesarean section in the setting of severe pulmonary hypertension requiring extracorporeal life support. General Thoracic And Cardiovascular Surgery 2016, 65: 532-534. PMID: 27888446, DOI: 10.1007/s11748-016-0729-x.Peer-Reviewed Original ResearchConceptsExtracorporeal membrane oxygenationFixed pulmonary hypertensionPulmonary hypertensionCesarean sectionVeno-arterial extracorporeal membrane oxygenationInitiation of ECMOHigh maternal mortality rateSudden hemodynamic collapseSevere pulmonary hypertensionExtracorporeal life supportWeeks of gestationMaternal mortality rateCardiogenic shockChest painHemodynamic collapseMembrane oxygenationClinical evaluationFemoral linesRapid cannulationMortality rateHypertensionLife supportPatientsDeliveryDyspnea
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