2023
Impact of intraoperative blood products, fluid administration, and persistent hypothermia on bleeding leading to reexploration after cardiac surgery
Shou B, Zhou A, Ong C, Alejo D, DiNatale J, Larson E, Lawton J, Schena S. Impact of intraoperative blood products, fluid administration, and persistent hypothermia on bleeding leading to reexploration after cardiac surgery. Journal Of Thoracic And Cardiovascular Surgery 2023, 168: 873-884.e4. PMID: 37839660, DOI: 10.1016/j.jtcvs.2023.10.011.Peer-Reviewed Original ResearchIntraoperative blood product transfusionIntensive care unit arrivalCore body temperatureBlood product transfusionCardiac surgeryPerioperative bleedingProduct transfusionCrystalloid administrationFluid administrationUnit arrivalRisk factorsAdult cardiac surgery patientsGreater postoperative morbidityIntraoperative blood productsSevere postoperative bleedingCardiac surgery patientsBlood product administrationIntravenous fluid administrationLower core body temperatureSuch risk factorsElectronic medical recordsPersistent hypothermiaPostoperative bleedingPostoperative morbidityIntraoperative fluid
2022
Causal determinants of postoperative length of stay in cardiac surgery using causal graphical learning
Lee JJR, Srinivasan R, Ong CS, Alejo D, Schena S, Shpitser I, Sussman M, Whitman GJR, Malinsky D. Causal determinants of postoperative length of stay in cardiac surgery using causal graphical learning. Journal Of Thoracic And Cardiovascular Surgery 2022, 166: e446-e462. PMID: 36154975, PMCID: PMC9968823, DOI: 10.1016/j.jtcvs.2022.08.012.Peer-Reviewed Original ResearchConceptsAortic valve replacement surgeryPostoperative lengthCoronary artery bypassValve replacement surgeryElectronic health record dataHealth record dataArtery bypassReplacement surgeryRetrospective electronic health record dataMean postoperative lengthCardiac surgery patientsRecord dataClinical knowledgeIndirect causesPreoperative dialysisPostoperative complicationsSurgery patientsCardiac surgeryPatient managementStayClinical protocolsPatientsSurgeryOperating roomStatistical associationEarly Reexploration for Bleeding Is Associated With Improved Outcome in Cardiac Surgery
Shou BL, Aravind P, Ong CS, Alejo D, Canner JK, Etchill EW, DiNatale J, Prokupets R, Esfandiary T, Lawton JS, Schena S. Early Reexploration for Bleeding Is Associated With Improved Outcome in Cardiac Surgery. The Annals Of Thoracic Surgery 2022, 115: 232-239. PMID: 35952856, DOI: 10.1016/j.athoracsur.2022.07.037.Peer-Reviewed Original ResearchConceptsCardiac surgeryActive bleedingAdult cardiac surgery patientsSingle-institution retrospective reviewMultivariable logistic regression modelCardiac surgery patientsEarly surgical interventionRisk-adjusted analysisLogistic regression modelsEarly reexplorationEligible patientsPostoperative bleedingNonoperative managementSurgery patientsRetrospective reviewUnivariable analysisMorbidity rateSurgical interventionCommon siteMediastinal structuresReexplorationKruskal-Wallis testMortality rateBleedingPatient harmDeep Learning to Predict Mortality After Cardiothoracic Surgery Using Preoperative Chest Radiographs
Raghu VK, Moonsamy P, Sundt TM, Ong CS, Singh S, Cheng A, Hou M, Denning L, Gleason TG, Aguirre AD, Lu MT. Deep Learning to Predict Mortality After Cardiothoracic Surgery Using Preoperative Chest Radiographs. The Annals Of Thoracic Surgery 2022, 115: 257-264. PMID: 35609650, PMCID: PMC11373441, DOI: 10.1016/j.athoracsur.2022.04.056.Peer-Reviewed Original ResearchConceptsMassachusetts General HospitalPreoperative chest radiographSTS-PROMIndex procedureC-statisticChest radiographsTesting cohortPostoperative mortalityCardiac surgeryMortality riskPostoperative mortality riskSTS-PROM scoreRisk of mortalityGood calibrationMGH patientsWomen's HospitalGeneral HospitalCardiothoracic surgeryThoracic surgeonsSurgeryMortalityPatientsHospitalCohortPreoperative CXR
2021
Leveraging Machine Learning to Predict 30-Day Hospital Readmission After Cardiac Surgery
Sherman E, Alejo D, Wood-Doughty Z, Sussman M, Schena S, Ong CS, Etchill E, DiNatale J, Ahmidi N, Shpitser I, Whitman G. Leveraging Machine Learning to Predict 30-Day Hospital Readmission After Cardiac Surgery. The Annals Of Thoracic Surgery 2021, 114: 2173-2179. PMID: 34890575, DOI: 10.1016/j.athoracsur.2021.11.011.Peer-Reviewed Original ResearchConceptsElectronic medical record dataDays of dischargeMedical record dataHospital readmissionThoracic Surgeons Adult Cardiac Surgery DatabaseArt performanceAdult Cardiac Surgery DatabaseRecord dataCardiac Surgery DatabaseLength of stayRandom forest modelFlexible machineTest setMachinePreoperative comorbiditiesPostoperative complicationsAnalysis cohortCardiac surgeryPreoperative variablesSurgery DatabaseIntraoperative riskInpatient careReadmissionRisk scoreRehabilitation facilityLate onset atrial fibrillation in patients undergoing surgical aortic valve replacement
Ong CS, Reinertsen E, Moonsamy P, Young K, Song S, Axtell AL, Wolfe SB, Mohan N, Jassar AS, Aguirre AD, Sundt TM. Late onset atrial fibrillation in patients undergoing surgical aortic valve replacement. Journal Of Cardiac Surgery 2021, 37: 285-289. PMID: 34699088, DOI: 10.1111/jocs.16093.Peer-Reviewed Original ResearchConceptsSurgical aortic valve replacementLate atrial fibrillationOnset atrial fibrillationAortic valve replacementAtrial fibrillationValve replacementHigher preoperative creatinine levelLate-onset atrial fibrillationNew-onset atrial fibrillationSingle-institution cohort analysisPreoperative atrial fibrillationPreoperative creatinine levelAortic valve diseaseRisk of mortalityAF interventionsAF prophylaxisPerioperative episodesEmergent surgeryLate mortalityCardiac surgeryCreatinine levelsMedical therapyUnderwent proceduresValve diseaseProphylactic interventionsRed blood cell storage duration and peri‐operative outcomes in paediatric cardiac surgery
Padiyath A, Lo BD, Ong CS, Goswami D, Steppan DA, Frank SM, Steppan J. Red blood cell storage duration and peri‐operative outcomes in paediatric cardiac surgery. Vox Sanguinis 2021, 116: 965-975. PMID: 33761164, DOI: 10.1111/vox.13098.Peer-Reviewed Original ResearchConceptsLength of stayRed blood cell (RBC) storage durationPediatric cardiac surgeryComposite morbidityRBC transfusion volumeCardiac surgeryOld bloodTransfusion volumePediatric cardiac surgery patientsMultivariable logistic regression modelFresh bloodRetrospective cohort studyCardiac surgery patientsPeri-operative outcomesRisk of morbidityRBC storage durationLonger durationRisk-adjusted modelsLogistic regression modelsCohort studySecondary outcomesSurgery patientsPediatric patientsPrimary outcomeClinical outcomes
2020
Nutrition Support After Cardiac Surgery: Lessons Learned From a Prospective Study
Ong CS, Yesantharao P, Brown PM, Canner JK, Brown TA, Sussman MS, Whitman GJR. Nutrition Support After Cardiac Surgery: Lessons Learned From a Prospective Study. Seminars In Thoracic And Cardiovascular Surgery 2020, 33: 109-115. PMID: 32610197, DOI: 10.1053/j.semtcvs.2020.06.043.Peer-Reviewed Original ResearchConceptsCardiac surgery patientsNutrition supportDaily caloric needsSurgery patientsCardiac surgeryCaloric needsPostoperative nutrition supportPercent of patientsMultivariable logistic regressionRisk of diarrheaPN supplementationPostpyloric feedsPostpyloric routeSemielemental formulaEnteral feedingParenteral nutritionCommon indicationMechanical ventilationProspective studySingle institutionTF volumeCommon reasonPatientsLogistic regressionMorbidityVasoactive and Inotropic Support, Tube Feeding, and Ischemic Gut Complications After Cardiac Surgery
Ong CS, Brown PM, Yesantharao P, Zhou X, Young A, Canner JK, Quinlan M, Brown EF, Sussman MS, Whitman GJR. Vasoactive and Inotropic Support, Tube Feeding, and Ischemic Gut Complications After Cardiac Surgery. Journal Of Parenteral And Enteral Nutrition 2020, 44: 1461-1467. PMID: 32010992, DOI: 10.1002/jpen.1769.Peer-Reviewed Original ResearchConceptsCardiac surgery patientsSurgery patientsTube feedsGut complicationsInotropic supportIntra-aortic balloon pumpElemental formula usePressor supportGastric routeBalloon pumpCardiac surgeryTube feedingTF administrationAcute embolusSingle institutionPatientsFormula useComplicationsHighest VIsDecreased amountDaysInotropicEmboliSurgeryMortality
2019
Trends and Updates on Cardiopulmonary Bypass Setup in Pediatric Cardiac Surgery
Medikonda R, Ong CS, Wadia R, Goswami D, Schwartz J, Wolff L, Hibino N, Vricella L, Nyhan D, Barodka V, Steppan J. Trends and Updates on Cardiopulmonary Bypass Setup in Pediatric Cardiac Surgery. Journal Of Cardiothoracic And Vascular Anesthesia 2019, 33: 2804-2813. PMID: 30738750, DOI: 10.1053/j.jvca.2019.01.025.Peer-Reviewed Original ResearchConceptsCardiac surgeryCardiopulmonary bypassPediatric cardiac surgery outcomesPediatric cardiac surgeryEvidence-based guidelinesCardiac surgery outcomesCardiopulmonary bypass managementUniform evidence-based guidelinesExtracorporeal circuit componentsInconsistent study resultsPediatric patientsClinical outcomesSurgery outcomesCardiopulmonary bypass (CPB) setupBypass managementPerfusion strategyPerfusion practiceSurgeryBypassCurrent literatureOutcomesConsiderable variabilityPatientsStudy resultsCrystalloids
2018
Surgical management of anomalous coronary arteries.
Ong CS, Cameron DE, Jacobs ML. Surgical management of anomalous coronary arteries. Annals Of Cardiothoracic Surgery 2018, 7: 604-610. PMID: 30505744, PMCID: PMC6219947, DOI: 10.21037/acs.2018.08.02.Peer-Reviewed Original ResearchSudden cardiac deathAnomalous coronary arteryCardiac surgerySurgical managementCoronary arteryCardiovascular intensive careOverall postoperative mortalityCoronary artery originCurrent surgical managementCoronary arterial circulationBest available evidencePostoperative mortalityCardiac deathLethal complicationSurgical treatmentArtery originIntensive careArterial circulationClinical significanceAvailable evidenceBenefit ratioSurgeryArteryMorbidityComplicationsA Review of Goal-Directed Cardiopulmonary Bypass Management in Pediatric Cardiac Surgery
Medikonda R, Ong CS, Wadia R, Goswami D, Schwartz J, Wolff L, Hibino N, Vricella L, Barodka V, Steppan J. A Review of Goal-Directed Cardiopulmonary Bypass Management in Pediatric Cardiac Surgery. World Journal For Pediatric And Congenital Heart Surgery 2018, 9: 565-572. PMID: 30157729, DOI: 10.1177/2150135118775964.Peer-Reviewed Original ResearchConceptsGoal-directed therapyVenous oxygen saturationPerfusion managementOxygen saturationCentral venous oxygen saturationGoal-directed perfusionVital clinical parametersEnd-organ perfusionPediatric cardiac surgeryCardiopulmonary bypass managementPatient's specific needsTransfusion ratePostoperative outcomesArterial pressureCardiac surgeryPerfusion flow rateClinical parametersPlatelet countPatient outcomesPostoperative monitoringCardiothoracic surgeryCoagulation stateBypass managementPerfusion pulsatilityPerfusion
2017
The use of 3D printing in cardiac surgery
Ong CS, Hibino N. The use of 3D printing in cardiac surgery. Journal Of Thoracic Disease 2017, 9: 2301-2302. PMID: 28932530, PMCID: PMC5594159, DOI: 10.21037/jtd.2017.07.73.Peer-Reviewed Original ResearchKommerell's diverticulumAortic archAberrant left subclavian arteryRight-sided aortic archPostoperative computed tomography scansFrozen elephant trunkLeft subclavian arteryComputed tomography scanSubclavian arteryUneventful recoveryCardiac surgerySurgical repairOperative timeCase reportTomography scanElephant trunkSurgical guideGraft shapePatientsSurgeryDiverticulumArchPatencyArteryAortaVirtual Surgery for Conduit Reconstruction of the Right Ventricular Outflow Tract
Ong CS, Loke YH, Opfermann J, Olivieri L, Vricella L, Krieger A, Hibino N. Virtual Surgery for Conduit Reconstruction of the Right Ventricular Outflow Tract. World Journal For Pediatric And Congenital Heart Surgery 2017, 8: 391-393. PMID: 28520540, PMCID: PMC5695863, DOI: 10.1177/2150135117692777.Peer-Reviewed Original ResearchConceptsRight ventricular outflow tractVentricular outflow tractCardiac surgeryOutflow tractPulmonary artery conduit replacementTranscatheter pulmonary valve implantationRV-PA conduitPulmonary valve implantationIndividual patient dataHistory of tetralogyPatient's own heartConduit sizeVirtual surgeryImplantation of prosthesesConduit replacementImplantation of devicesPreoperative magnetic resonance imaging (MRI) dataPulmonary atresiaYoung adolescent malesValve implantationConduit reconstructionIntrathoracic spaceRight ventricleMagnetic resonance imaging dataPatient education
2016
Constrictive Pericarditis Following Correction of Partial Anomalous Pulmonary Venous Drainage
Ong CS, Shankar S, Yip JWL, Tay ELW, Teo LLS, Quek SC. Constrictive Pericarditis Following Correction of Partial Anomalous Pulmonary Venous Drainage. World Journal For Pediatric And Congenital Heart Surgery 2016, 8: 540-542. PMID: 27647341, DOI: 10.1177/2150135116652116.Peer-Reviewed Original ResearchConceptsConstrictive pericarditisPartial anomalous pulmonary venous drainagePartial anomalous pulmonary venous connectionPersistent right heart failureAnomalous pulmonary venous connectionAnomalous pulmonary venous drainagePulmonary valve replacementRight heart failurePulmonary venous connectionPulmonary venous drainageRepair of tetralogyFailure of surgeryCongenital cardiac surgeryMagnetic resonance imagingRadical pericardiectomyResidual complicationsValve replacementVenous connectionCardiac surgeryHeart failureCardiac failureMedical managementVenous drainageBetter outcomesResonance imaging
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