2021
An asymmetric structure of the filament is key to inducing flagellar curvature and enabling motility in the Leptospira spirochete
San Martin F, Gibson K, Trajtenberg F, Brady M, Wunder E, Picardeau M, Mechaly A, Ko A, Sindelar C, Buschiazzo A. An asymmetric structure of the filament is key to inducing flagellar curvature and enabling motility in the Leptospira spirochete. Acta Crystallographica Section A: Foundations And Advances 2021, 77: c291-c291. DOI: 10.1107/s0108767321093910.Peer-Reviewed Original Research
2020
An asymmetric sheath controls flagellar supercoiling and motility in the leptospira spirochete
Gibson KH, Trajtenberg F, Wunder EA, Brady MR, San Martin F, Mechaly A, Shang Z, Liu J, Picardeau M, Ko A, Buschiazzo A, Sindelar CV. An asymmetric sheath controls flagellar supercoiling and motility in the leptospira spirochete. ELife 2020, 9: e53672. PMID: 32157997, PMCID: PMC7065911, DOI: 10.7554/elife.53672.Peer-Reviewed Original ResearchConceptsCryo-electron tomographyKey functional attributesNative flagellar filamentsHigh-resolution cryo-electron tomographyPeriplasmic spaceSheath proteinStructural basisFlagellar filamentsLeptospira spirochetesSpirochete bacteriaEntire cellFunctional attributesX-ray crystallographyImportant pathogenSupercoilingMotilityBacteriaFilamentsCell bodiesFlagellaSpirochetesProteinFlagellinDistinctive meansEndoflagellaIn Vitro Configuration of Munc13-1 Bridging of Phospholipid Bilayers at Resting Conditions
Grushin K, Sundaram R, Gibson K, Krishnakumar S, Sindelar C, Rothman J. In Vitro Configuration of Munc13-1 Bridging of Phospholipid Bilayers at Resting Conditions. Biophysical Journal 2020, 118: 400a. DOI: 10.1016/j.bpj.2019.11.2272.Peer-Reviewed Original Research
2018
Novel Architecture and Composition of a Bacterial Flagellum in the Spirochete Leptospira biflexa
Gibson K, Wunder E, Liu J, Trajtenberg F, Buschiazzo A, Ko A, Sindelar C. Novel Architecture and Composition of a Bacterial Flagellum in the Spirochete Leptospira biflexa. Biophysical Journal 2018, 114: 371a. DOI: 10.1016/j.bpj.2017.11.2056.Peer-Reviewed Original Research
2017
Cryo-Electron Tomography and Sub-Volume Averaging Reveal the Asymmetric Structure of the Leptospira Flagellla
Gibson K, Sindelar C. Cryo-Electron Tomography and Sub-Volume Averaging Reveal the Asymmetric Structure of the Leptospira Flagellla. Biophysical Journal 2017, 112: 577a. DOI: 10.1016/j.bpj.2016.11.3107.Peer-Reviewed Original Research
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