Long-Term Air Pollution Exposure and Severity of Idiopathic Pulmonary Fibrosis: Data from the Idiopathic Pulmonary Fibrosis Prospective Outcomes (IPF-PRO) Registry.
Sack C, Wojdyla D, MacMurdo M, Gassett A, Kaufman J, Raghu G, Redlich C, Li P, Olson A, Leonard T, Todd J, Neely M, Snyder L, Gulati M, Baker A, Beegle S, Belperio J, Condos R, Cordova F, Southern B, Dilling D, Fitzgerald J, Flaherty K, Gibson K, Gulati M, Guntupalli K, Gupta N, Case A, Hotchkin D, Huie T, Kaner R, Kim H, Lancaster L, Lasky J, Lee D, Liesching T, Lipchik R, Lobo J, Luckhardt T, Mageto Y, Kokoszynska M, Morrison L, Namen A, Oldham J, Paul T, Zhang D, Porteous M, Raj R, Ramaswamy M, Russell T, Sachs P, Safdar Z, Shafazand S, Siddiqi A, Fowler R, Strek M, Rivas-Perez H, Tabak J, Walia R, Whelan T. Long-Term Air Pollution Exposure and Severity of Idiopathic Pulmonary Fibrosis: Data from the Idiopathic Pulmonary Fibrosis Prospective Outcomes (IPF-PRO) Registry. Annals Of The American Thoracic Society 2025, 22: 378-386. PMID: 39531618, DOI: 10.1513/annalsats.202404-382oc.Peer-Reviewed Original ResearchAssociated with worse qualityExposure to air pollutionGene-environment interactionsQuality of lifePollution exposureEffects of long-term exposure to air pollutionLong-term exposure to PM<sub>2.5</sub> anLong-term exposure to air pollutionWorse qualityParticipant's residential addressQuality of life measuresNon-Hispanic whitesExposure to PM<sub>2.5</sub>Multi-pollutant modelsYears of follow-upCox proportional hazards modelsLower FVC %Residential addressesProportional hazards modelIPF-PRO RegistryMultivariate regression modelEffect modificationEuroQol scoresLife measuresEnrollment date
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