2025
Mortality, Hepatic Decompensation, and Cardiovascular Outcomes in Lean vs. Non-lean MASLD Cirrhosis: A Veterans Affairs Cohort Study
Njei B, Mezzacappa C, John B, Serper M, Kaplan D, Taddei T, Mahmud N. Mortality, Hepatic Decompensation, and Cardiovascular Outcomes in Lean vs. Non-lean MASLD Cirrhosis: A Veterans Affairs Cohort Study. Digestive Diseases And Sciences 2025, 70: 802-813. PMID: 39779587, PMCID: PMC11839701, DOI: 10.1007/s10620-024-08764-4.Peer-Reviewed Original ResearchConceptsNon-lean individualsAll-cause mortalityMajor adverse cardiovascular eventsIncreased risk of all-cause mortalityRisk of all-cause mortalityVeterans Health AdministrationRisk of hepatic decompensationPrevalence of diabetesRisk of cardiovascular mortalityHepatic decompensationHigher mortality riskCardiovascular-related mortalityCox proportional hazards modelsCohort study of patientsCardiovascular outcomesIncident major adverse cardiovascular eventsRetrospective cohort study of patientsProportional hazards modelNon-HispanicRetrospective cohort studyCompeting risk regressionHealth AdministrationMultivariate Cox proportional hazards modelLean individualsAssessed associations
2024
The impact of overweight and obesity on health outcomes in the United States from 1990 to 2021
Al Ta'ani O, Al‐Ajlouni Y, Aleyadeh W, Al‐Bitar F, Alsakarneh S, Saadeh A, Alhuneafat L, Njei B. The impact of overweight and obesity on health outcomes in the United States from 1990 to 2021. Diabetes Obesity And Metabolism 2024, 26: 5455-5465. PMID: 39261301, DOI: 10.1111/dom.15924.Peer-Reviewed Original ResearchConceptsDisability-adjusted life yearsAge-standardized death ratesSocio-demographic indexBody mass indexHigher body mass indexHealth outcomesDeath rateAge-standardized disability-adjusted life yearsComprehensive public health strategyGlobal Burden of Disease dataBurden of disease dataAge-standardized DALY rateAnnual percentage changePublic health strategiesSignificant public health challengeElevated body mass indexPublic health challengeUnited StatesImpact public healthHealth strategiesDALY ratesOlder adultsEnvironmental interventionsGlobal burdenHealth challengesCardiovascular morbidity and mortality in lean vs. non-lean MASLD: A comprehensive meta-analysis
Nso N, Mergen D, Ikram M, Macrinici V, Hussain K, Lee K, Ugwendum D, Trimingham M, Balasubramanian S, Sam R, Njei B. Cardiovascular morbidity and mortality in lean vs. non-lean MASLD: A comprehensive meta-analysis. Current Problems In Cardiology 2024, 49: 102569. PMID: 38599554, DOI: 10.1016/j.cpcardiol.2024.102569.Peer-Reviewed Original ResearchConceptsOdds ratioConfidence intervalsCardiovascular mortality riskPooled odds ratioAll-cause mortalityCardiometabolic profileMortality oddsMortality riskSecondary outcomesPrimary outcomeOddsMACE rateCardiovascular morbidityMeta-analysisCardiovascular outcomesLiver diseaseLean individualsSteatotic liver diseasePublication dateSample sizePatientsMACEOutcomesCohortMortality
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