2024
NCS-1 protein regulates TRPA1 channel through the PI3K pathway in breast cancer and neuronal cells
Sánchez J, Alemán A, Henao J, Olaya J, Ehrlich B. NCS-1 protein regulates TRPA1 channel through the PI3K pathway in breast cancer and neuronal cells. Journal Of Physiology And Biochemistry 2024, 80: 451-463. PMID: 38564162, PMCID: PMC11074019, DOI: 10.1007/s13105-024-01016-z.Peer-Reviewed Original ResearchConceptsTransient receptor potential channel ankyrin 1Breast cancerPI3K pathwayNCS-1Chemotherapy-induced peripheral neuropathyCa2+ channelsK pathwayCa2+ influxNCS-1 expressionBreast cancer cellsCa2+ sensorCa2+ homeostasisCa2+ dynamicsNeuronal calcium sensor-1MDA-MB-231Fura-2Open probabilityPain sensationAnkyrin 1Peripheral neuropathyTRPA1 channelsCo-immunoprecipitationChannel functionRegulatory componentsCellular pathways
2009
The Amplification Of InsP3R Activity By NCS-1 Is Attenuated By Medications Used In The Treatment Of Bipolar Disorder
Schulze C, Olofsson J, Ehrlich B. The Amplification Of InsP3R Activity By NCS-1 Is Attenuated By Medications Used In The Treatment Of Bipolar Disorder. Biophysical Journal 2009, 96: 96a. DOI: 10.1016/j.bpj.2008.12.407.Peer-Reviewed Original Research