2025
Morphological alterations of the thymus gland in individuals with schizophrenia
Zhao Q, Wei X, Yu W, Li X, Gao Z, Liu S, Liu Z, Wang K, Bishop J, Hu H, Luo C, Xiao Y, Hu N, Tao B, Zhu F, Gong Q, Lui S. Morphological alterations of the thymus gland in individuals with schizophrenia. Molecular Psychiatry 2025, 1-11. PMID: 40038543, DOI: 10.1038/s41380-025-02946-w.Peer-Reviewed Original ResearchAverage CT attenuationChest computed tomographyCT attenuationImmunometabolic profileThymic morphologySubtype 1Subtype 2Evidence of immunological abnormalitiesMaximal thicknessAnteroposterior distancePatient subtypesLow CT attenuationMorphological alterationsCase-control comparisonImmunological abnormalitiesThymic sizeLymphocyte countSchizophreniaComputed tomographyLipid measurementsThymus glandImmune hypothesisPatientsImmune systemSubtypes
2016
Cellular Phenotypic Analysis of Macrophage Activation Unveils Kinetic Responses of Agents Targeting Phosphorylation
Cao Q, Yao J, Li H, Tao B, Cai Y, Xiao P, Cheng H, Ke Y. Cellular Phenotypic Analysis of Macrophage Activation Unveils Kinetic Responses of Agents Targeting Phosphorylation. SLAS DISCOVERY 2016, 22: 51-57. PMID: 27554457, DOI: 10.1177/1087057116663166.Peer-Reviewed Original ResearchConceptsEndpoint assayHigh-throughput mannerRegulation of macrophage activationImpedance-based assayHost immune systemCell response profilesMicrobial productsPathogen clearanceGlobal screeningPhysiologically relevant dataMacrophage functionCellular impedanceMacrophage activationAssayPreventing autoimmune diseasesImmune systemKinase/phosphatasePlastic cellsPathogensMacrophagesAutoimmune diseasesReal-timeHostReal time
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