2021
Identification of homozygous mutations for hearing loss
Dianatpour M, Smith E, Hashemi SB, Farazifard MA, Nezafat N, Razban V, Mani A. Identification of homozygous mutations for hearing loss. Gene 2021, 778: 145464. PMID: 33524517, PMCID: PMC7987747, DOI: 10.1016/j.gene.2021.145464.Peer-Reviewed Original ResearchConceptsAutosomal recessive nonsyndromic deafnessWhole-exome sequencingEfficacy of WESHomozygous mutationGenetic screeningSanger sequencingCause of deafnessConsanguineous unionsNew pathogenic mutationsCommon sensory disorderMissense mutationsHigh prevalenceSensory disordersHomozygous missense mutationIranian populationEarly screeningNovel therapeuticsSingle gene disordersExome sequencingMajor genetic componentESRRB genePathogenic mutationsSpectrum of genesFuture genetic screeningRecessive fashion
2012
Prevalence of Obesity and Traditional Cardiovascular Risk Factors in South Asians
Khanna P, Mani A. Prevalence of Obesity and Traditional Cardiovascular Risk Factors in South Asians. Current Cardiovascular Risk Reports 2012, 6: 112-119. DOI: 10.1007/s12170-012-0220-x.Peer-Reviewed Original ResearchRisk factorsCardiovascular diseaseSouth AsiansTraditional cardiovascular risk factorsCardiovascular risk factorsCVD risk factorsPrevalence of obesityLifestyle factorsNovel biomarkersGenetic predispositionHealthcare providersDisease controlNovel therapeuticsMajor causeGenetic causePrevalenceObesityWestern worldAsiansCauseImportant contributorDiabetesSpecific differencesFactorsMortality