Person-centered analyses reveal that developmental adversity at moderate levels and neural threat/safety discrimination are associated with lower anxiety in early adulthood
Sisk L, Keding T, Ruiz S, Odriozola P, Kribakaran S, Cohodes E, McCauley S, Zacharek S, Hodges H, Haberman J, Pierre J, Caballero C, Baskin-Sommers A, Gee D. Person-centered analyses reveal that developmental adversity at moderate levels and neural threat/safety discrimination are associated with lower anxiety in early adulthood. Communications Psychology 2025, 3: 31. PMID: 40044923, PMCID: PMC11882445, DOI: 10.1038/s44271-025-00193-x.Peer-Reviewed Original ResearchNeural activityAdverse exposuresMiddle childhoodLower anxietyAssociated with lower anxietyWithin-person combinationsPerson-centered analysesPerson-centered approachHigher neural activityPatterns of adversity exposureCorticolimbic circuitryModerate adversityParsing heterogeneityAnxiety symptomsSafety learningDevelopmental adversityLatent profilesLifetime adversityNeurobiological functionsFuture anxietyAnxietyEarly adulthoodAssociated with processesAdversityYoung adults
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