2025
Brain Development and the Risk for Substance Use, Misuse, and Substance Use Disorders
Ruiz S, Casey B, Baskin-Sommers A. Brain Development and the Risk for Substance Use, Misuse, and Substance Use Disorders. 2025, 675-684. DOI: 10.1093/med/9780197640654.003.0049.Peer-Reviewed Original ResearchSubstance use disordersSubstance useMaintenance of substance use disordersFamily history of substance use disorderHistory of substance use disorderRegulation of rewardStress-related circuitryEarly life adversityAdolescent substance useCognitive controlPersonality traitsSensation seekingLife adversityNeurodevelopmental changesUse disorderAbstract AdolescentsIntervention scienceInfluence of peersSubstance exposureBrain developmentAdolescentsDisordersRewardMisuseCircuitry
2020
Influences of early‐life stress on frontolimbic circuitry: Harnessing a dimensional approach to elucidate the effects of heterogeneity in stress exposure
Cohodes EM, Kitt ER, Baskin‐Sommers A, Gee DG. Influences of early‐life stress on frontolimbic circuitry: Harnessing a dimensional approach to elucidate the effects of heterogeneity in stress exposure. Developmental Psychobiology 2020, 63: 153-172. PMID: 32227350, DOI: 10.1002/dev.21969.Peer-Reviewed Original ResearchConceptsEarly life stressFrontolimbic circuitryStress exposurePhysical health problemsEffects of stressCircuit maturationGlucocorticoid receptorHealth problemsMajority of studiesMental healthExposure influencePsychobiological effectsDimensional approachEarly experienceDifferential outcomesOutcomesSubsequent vulnerabilityRiskVast heterogeneityExposureInnervationCircuitryBrainSeverityCaregivers
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