2025
Comparative Performance of Machine Learning Models in Reducing Unnecessary Targeted Prostate Biopsies
Chen F, Esmaili R, Khajir G, Zeevi T, Gross M, Leapman M, Sprenkle P, Justice A, Arora S, Weinreb J, Spektor M, Huber S, Humphrey P, Levi A, Staib L, Venkataraman R, Martin D, Onofrey J. Comparative Performance of Machine Learning Models in Reducing Unnecessary Targeted Prostate Biopsies. European Urology Oncology 2025 PMID: 39924390, DOI: 10.1016/j.euo.2025.01.005.Peer-Reviewed Original ResearchProstate cancerPrediction of clinically significant prostate cancerClinical dataProstate-specific antigen levelClinically significant prostate cancerProstate magnetic resonance imagingSeverity of prostate cancerCombination of clinical featuresPrediction of csPCaSignificant prostate cancerProstate Imaging-ReportingCore needle biopsyRetrospective analysis of dataDecision curve analysisReducing unnecessary biopsiesProstate cancer diagnosisReceiver operating characteristic curveArea under the receiver operating characteristic curveFalse-negative rateMagnetic resonance imagingPersonalized risk assessmentAntigen levelsNeedle biopsyPatient ageUnnecessary biopsies
2021
International Multi-Site Initiative to Develop an MRI-Inclusive Nomogram for Side-Specific Prediction of Extraprostatic Extension of Prostate Cancer
Wibmer AG, Kattan MW, Alessandrino F, Baur ADJ, Boesen L, Franco FB, Bonekamp D, Campa R, Cash H, Catalá V, Crouzet S, Dinnoo S, Eastham J, Fennessy FM, Ghabili K, Hohenfellner M, Levi AW, Ji X, Løgager V, Margolis DJ, Moldovan PC, Panebianco V, Penzkofer T, Puech P, Radtke JP, Rouvière O, Schlemmer HP, Sprenkle PC, Tempany CM, Vilanova JC, Weinreb J, Hricak H, Shukla-Dave A. International Multi-Site Initiative to Develop an MRI-Inclusive Nomogram for Side-Specific Prediction of Extraprostatic Extension of Prostate Cancer. Cancers 2021, 13: 2627. PMID: 34071842, PMCID: PMC8198352, DOI: 10.3390/cancers13112627.Peer-Reviewed Original ResearchExtraprostatic extensionProstate cancerProstate-specific antigen densityLogistic regression modelsSide-specific extraprostatic extensionConsecutive patientsMRI findingsPatient ageNomogram modelMRI featuresMRI variablesAntigen densityBiopsy dataProstatectomy specimensBenchmark modelMulti-site studyMulti-site initiativesNomogramCancerCharacteristic curveBiopsyPatientsStatistical modelRegression modelsImaging-derived data
2004
Urinary bladder biopsy with denuded mucosa: Denuding cystitis—Cytopathologic correlates
Parwani AV, Levi AW, Epstein JI, Ali SZ. Urinary bladder biopsy with denuded mucosa: Denuding cystitis—Cytopathologic correlates. Diagnostic Cytopathology 2004, 30: 297-300. PMID: 15108225, DOI: 10.1002/dc.10406.Peer-Reviewed Original ResearchConceptsHigh-grade urothelial carcinomaUrothelial carcinomaUrinary cytologyFollowing histologic subtypesUrinary bladder biopsiesPositive urinary cytologySurgical pathology filesInvasive urothelial carcinomaOptimal patient managementRecurrent urothelial carcinomaJohns Hopkins HospitalPatient agePathology filesHistologic subtypeBladder biopsiesHistologic diagnosisBladder mucosaFlat carcinomaSensitive modalityPatient managementCytologic diagnosisCystitisCytologic studyTissue biopsiesPatients
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