2020
Modeling Combination Hepatitis C Virus Treatment and Prevention Strategies in a Network of People Who Inject Drugs in the United States
Zelenev A, Li J, Shea P, Hecht R, Altice FL. Modeling Combination Hepatitis C Virus Treatment and Prevention Strategies in a Network of People Who Inject Drugs in the United States. Clinical Infectious Diseases 2020, 72: 755-763. PMID: 32060534, PMCID: PMC7935393, DOI: 10.1093/cid/ciaa142.Peer-Reviewed Original ResearchConceptsOpioid agonist therapySyringe services programHepatitis C virus (HCV) treatmentC virus treatmentHCV prevalenceHCV microeliminationHCV TasPHCV treatmentPrevention strategiesVirus treatmentTasP strategyHigh HCV prevalenceMicroelimination of HCVHuman immunodeficiency virusHCV treatment coverageOAT coverageAgonist therapyImmunodeficiency virusTreatment coverageMicroeliminationPrevention impactPrevalenceComplimentary interventionsHCVPWID
2019
Effect of expanding opioid agonist therapies on the HIV epidemic and mortality in Ukraine: a modelling study
Tan J, Altice FL, Madden LM, Zelenev A. Effect of expanding opioid agonist therapies on the HIV epidemic and mortality in Ukraine: a modelling study. The Lancet HIV 2019, 7: e121-e128. PMID: 31879250, PMCID: PMC7289179, DOI: 10.1016/s2352-3018(19)30373-x.Peer-Reviewed Original ResearchConceptsOpioid agonist therapyNew HIV infectionsHigh HIV burdenHIV infectionMinistry of HealthOAT coverageAgonist therapyHIV burdenHIV incidenceBuprenorphine maintenance therapyPublic Health CenterMaintenance therapyHIV outcomesHIV prevalenceHIV transmissionMedication procurementHIV epidemicHealth centersHIV preventionTreatment goalsPWIDOAT expansionDisease controlSexual riskInfection
2018
Estimating HIV and HCV prevalence among people who inject drugs in 5 Ukrainian cities using stratification-based respondent driven and random sampling
Zelenev A, Shea P, Mazhnaya A, Meteliuk A, Pykalo I, Marcus R, Fomenko T, Prokhorova T, Altice FL. Estimating HIV and HCV prevalence among people who inject drugs in 5 Ukrainian cities using stratification-based respondent driven and random sampling. International Journal Of Drug Policy 2018, 67: 91-101. PMID: 30503695, PMCID: PMC6537868, DOI: 10.1016/j.drugpo.2018.09.010.Peer-Reviewed Original ResearchConceptsHCV prevalenceHIV prevalenceHCV prevalence estimatesHigh HCV prevalencePrevalence of HIVCross-sectional studyLow-resource settingsInverse probability weightsHCV antibodiesHCV infectionTreatment strategiesHIVTreatment prioritiesPrevalence estimatesHealth outcomesBetter preventionPrevalenceLocal epidemicsHCVPWIDOverall sampleSelection biasPreventionProbability weightsRegular basisOpioid Agonist Treatment and Improved Outcomes at Each Stage of the HIV Treatment Cascade in People Who Inject Drugs in Ukraine
Mazhnaya A, Marcus R, Bojko MJ, Zelenev A, Makarenko I, Pykalo I, Filippovych S, Dvoriak S, Altice FL. Opioid Agonist Treatment and Improved Outcomes at Each Stage of the HIV Treatment Cascade in People Who Inject Drugs in Ukraine. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2018, 79: 288-295. PMID: 30312275, PMCID: PMC8215524, DOI: 10.1097/qai.0000000000001827.Peer-Reviewed Original ResearchConceptsOpioid agonist treatmentHIV treatment cascadeTreatment cascadeAgonist treatmentIndependent factorsHepatitis C virus testingOpioid-dependent PWIDOpioid use disorderClinical care settingsLogistic regression modelsOAT coverageAntiretroviral therapyHIV careUNAIDS 90HIV preventionImproved outcomesTreatment strategiesCare settingsVirus testingNationwide studyPWIDUse disordersOAT expansionHIVCareHepatitis C virus status awareness and test results confirmation among people who inject drugs in Ukraine
Iakunchykova O, Meteliuk A, Zelenev A, Mazhnaya A, Tracy M, Altice FL. Hepatitis C virus status awareness and test results confirmation among people who inject drugs in Ukraine. International Journal Of Drug Policy 2018, 57: 11-17. PMID: 29655101, PMCID: PMC5994183, DOI: 10.1016/j.drugpo.2018.03.022.Peer-Reviewed Original ResearchConceptsAnti-HCV testIndependent correlatesHCV testingPositive statusAnti-HCV positive statusAnti-HCV positivityHCV treatment cascadeHCV-positive statusOpioid-dependent PWIDRegular HCV testingHIV-negative participantsPositive test resultsChronic HCVHCV prevalenceStatus awarenessHCV infectionHCV preventionTreatment cascadeTreatment strategiesTreatment utilizationNegative participantsPWIDTreatment experienceHCVConfirmatory testing
2016
The complex interplay of social networks, geography and HIV risk among Malaysian Drug Injectors: Results from respondent-driven sampling
Zelenev A, Long E, Bazazi AR, Kamarulzaman A, Altice FL. The complex interplay of social networks, geography and HIV risk among Malaysian Drug Injectors: Results from respondent-driven sampling. International Journal Of Drug Policy 2016, 37: 98-106. PMID: 27639995, PMCID: PMC5102779, DOI: 10.1016/j.drugpo.2016.08.008.Peer-Reviewed Original ResearchConceptsHIV statusHIV transmissionClean needlesRecent injection partnersHigh-risk populationRisk reduction interventionsTargeting of interventionsPublic health surveillanceRespondent-driven samplingInjection partnersHIV preventionHIV riskTreatment coverageDrug injectorsHIVPrevention strategiesPWIDHealth surveillanceGreater Kuala LumpurKuala LumpurInterventionSurveillanceImportant mechanismStatus