2025
Serial Lactate in Clinical Medicine - A Narrative Review.
Falter F, Tisherman S, Perrino A, Kumar A, Bush S, Nordström L, Pathan N, Liu R, Mebazaa A. Serial Lactate in Clinical Medicine - A Narrative Review. Journal Of Intensive Care Medicine 2025, 8850666241303460. PMID: 39925111, DOI: 10.1177/08850666241303460.Peer-Reviewed Original ResearchResponse to therapyWarning ScoreAcute clinical areasHospital IT systemsElectronic patient recordsPoint of careNursing workforceClinical medicineDeteriorating patientsClinical areasSerial lactateMultidisciplinary groupHospital areasPrognostic guidePatient recordsLactate clearanceTreatment decisionsClinical utilityIntensive careEmergency roomPatient statusLactate levelsDisciplines of clinical medicineTherapyOperating roomMind the Gap: Wearable Lactate and Glucose Monitors for Hospitalized Patients
Guzzi J, Falter F, Kumar A, Perrino A. Mind the Gap: Wearable Lactate and Glucose Monitors for Hospitalized Patients. Cureus 2025, 17: e78536. PMID: 40062120, PMCID: PMC11886925, DOI: 10.7759/cureus.78536.Peer-Reviewed Original Research
2024
Same-Day Primary Care Referral Versus Usual Care for Patients With Elevated Blood Pressures Seen in a Preoperative Clinic
Butler S, Holt N, Dai F, Quick C, Kravetz J, Perrino A, Schonberger R. Same-Day Primary Care Referral Versus Usual Care for Patients With Elevated Blood Pressures Seen in a Preoperative Clinic. Cureus 2024, 16: e58401. PMID: 38756290, PMCID: PMC11098054, DOI: 10.7759/cureus.58401.Peer-Reviewed Original ResearchPrimary care referralsPrimary care groupsCare referralUsual careCare groupPreoperative clinicQuality improvementCare coordination effortsLong-term health outcomesPrimary care visitsPrimary care appointmentsCohort of US veteransMonths post-interventionSame-day referralElectronic health recordsBlood pressureSurgical care episodesHypertension treatmentProspective QI projectPreoperative evaluation clinicImprove BP controlQI projectCare appointmentsPreoperative clinic visitPrimary care
2023
Severe Pulmonary Hypertension Meets Intraperitoneal Surgery: No Place to Inflate?
Hickey T, Jayakumar S, Perrino A. Severe Pulmonary Hypertension Meets Intraperitoneal Surgery: No Place to Inflate? Cureus 2023, 15: e35318. PMID: 36968928, PMCID: PMC10038649, DOI: 10.7759/cureus.35318.Peer-Reviewed Original ResearchSevere pulmonary hypertensionPulmonary hypertensionPoor operative outcomesRight ventricular preloadRisk-benefit ratioElective cholecystectomyPneumoperitoneum resultsPerioperative managementVentricular preloadLaparoscopic approachOperative outcomesIntraperitoneal surgeryMechanical ventilationCardiac outputFavorable outcomeSuccessful case managementLaparoscopic proceduresCardiopulmonary insultCase managementMultidisciplinary approachHypertensionPatientsSurgeryOutcomesDeleterious effects
2020
Right ventricular function during and after thoracic surgery.
Gelzinis T, Assaad S, Perrino A. Right ventricular function during and after thoracic surgery. Current Opinion In Anaesthesiology 2020, 33: 27-36. PMID: 31724957, DOI: 10.1097/aco.0000000000000809.Peer-Reviewed Original ResearchConceptsRV dysfunctionAcute RV dysfunctionNew echocardiographic parametersPulmonary arterial capacitancePulmonary vascular resistanceRight ventricular dysfunctionRight ventricular functionAvailable diagnostic modalitiesPulmonary capacitanceEchocardiographic parametersPulmonary hypertensionVascular resistanceVentricular dysfunctionLung resectionPulmonary resectionHeart failureVentricular functionPreoperative assessmentRisk stratificationThoracic surgeryRisk factorsDisease progressionClinical significanceDiagnostic modalitiesClinical relevance
2002
Role of Transesophageal Echocardiography in Noncardiac Surgery
Reeves S, Perrino A. Role of Transesophageal Echocardiography in Noncardiac Surgery. ASA Refresher Courses In Anesthesiology 2002, 30: 147-158. DOI: 10.1097/00126869-200230010-00013.Peer-Reviewed Original ResearchTransient neurological symptoms after subarachnoid meperidine.
Lewis W, Perrino A. Transient neurological symptoms after subarachnoid meperidine. Anesthesia & Analgesia 2002, 94: 213-4, table of contents. PMID: 11772831, DOI: 10.1097/00000539-200201000-00041.Peer-Reviewed Original Research
2001
Hemodynamic-Induced Changes in Aortic Valve Area: Implications for Doppler Cardiac Output Determinations
Gray P, Perrino A. Hemodynamic-Induced Changes in Aortic Valve Area: Implications for Doppler Cardiac Output Determinations. Anesthesia & Analgesia 2001, 92: 584-589. DOI: 10.1213/00000539-200103000-00006.Peer-Reviewed Original ResearchConceptsAortic valve areaCardiac outputValve areaDobutamine infusionDoppler cardiac output determinationsSystolic blood pressureAortic flow velocityCardiac output determinationsDobutamine doseEchocardiographic variablesBlood pressureTransesophageal echocardiographyAVA measurementsAortic flowProcedural timeCO calculationsMin increaseOutput determinationHemodynamicsInfusionProbe manipulationEchocardiographyDobutaminePatientsCO protocolHemodynamic-induced changes in aortic valve area: implications for Doppler cardiac output determinations.
Gray P, Perrino A. Hemodynamic-induced changes in aortic valve area: implications for Doppler cardiac output determinations. Anesthesia & Analgesia 2001, 92: 584-9. PMID: 11226082, DOI: 10.1097/00000539-200103000-00006.Peer-Reviewed Original ResearchConceptsAortic valve areaDoppler cardiac output determinationsCardiac outputValve areaDobutamine infusionCardiac output determinationsSystolic blood pressureAortic flow velocityAortic blood flowOutput determinationEchocardiographic variablesBlood pressureDobutamine doseTransesophageal echocardiographyAVA measurementsAortic flowProcedural timeCO calculationsBlood flowMin increaseInfusionHemodynamicsProbe manipulationEchocardiographyDobutamine
2000
Combination of Two Standard Pneumatic Calf Compression Devices to Fit the Morbidly Obese
Winslow K, Hartmannsgruber M, Chung J, Perrino A. Combination of Two Standard Pneumatic Calf Compression Devices to Fit the Morbidly Obese. Anesthesiology 2000, 93: 1159. PMID: 11020783, DOI: 10.1097/00000542-200010000-00056.Peer-Reviewed Original ResearchRoom 220-222, 10/18/2000 10: 30 AM - 12: 00 PM (PD) Comparison of Alternative Methods for Intraoperative Cardiac Output Determination: Fick Partial Rebreathing CO2 and Transesophogeal Echoca rdiography
Gray P, Perrino A. Room 220-222, 10/18/2000 10: 30 AM - 12: 00 PM (PD) Comparison of Alternative Methods for Intraoperative Cardiac Output Determination: Fick Partial Rebreathing CO2 and Transesophogeal Echoca rdiography. Anesthesiology 2000, 93: a-589. DOI: 10.1097/00000542-200009001-00589.Peer-Reviewed Original Research
1999
Multiplane Transesophageal Echocardiographic Acquisition of Ascending Aortic Flow Velocities: A Comparison with Established Techniques
Harris S, Luther M, Perrino A. Multiplane Transesophageal Echocardiographic Acquisition of Ascending Aortic Flow Velocities: A Comparison with Established Techniques. Journal Of The American Society Of Echocardiography 1999, 12: 754-760. PMID: 10477420, DOI: 10.1016/s0894-7317(99)70026-x.Peer-Reviewed Original ResearchConceptsVelocity time integralAortic flow velocityTransesophageal echocardiographySuprasternal DopplerMonoplane transesophageal echocardiographyAortic flowContinuous wave Doppler interrogationMaximal aortic flow velocityUtility of TEEWave Doppler interrogationContinuous wave Doppler techniqueAortic blood flowMultiplane transesophageal echocardiographyWave Doppler techniqueElective surgeryValvular functionDoppler interrogationCardiac performanceEchocardiographic techniquesBlood flowPatientsDoppler techniqueImaging planesBias analysisFlow velocity
1998
Intraoperative Determination of Cardiac Output Using Multiplane Transesophageal Echocardiography
Perrino A, Harris S, Luther M. Intraoperative Determination of Cardiac Output Using Multiplane Transesophageal Echocardiography. Anesthesiology 1998, 89: 350-357. PMID: 9710392, DOI: 10.1097/00000542-199808000-00010.Peer-Reviewed Original ResearchTRANSESOPHAGEAL ECHOCARDIOGRAPHIC (TEE) ASSESSMENT OF VENOUS RETURN DURING LAPAROSCOPIC CHOLECYSTECTOMY
Harris, Cohen I, Luther M, Perrino A. TRANSESOPHAGEAL ECHOCARDIOGRAPHIC (TEE) ASSESSMENT OF VENOUS RETURN DURING LAPAROSCOPIC CHOLECYSTECTOMY. Anesthesia & Analgesia 1998, 86: 209s.. DOI: 10.1097/00000539-199802001-00207.Peer-Reviewed Original Research
1997
A942 AN ON-LINE DIGITAL ECHOCARDIOGRAPHY LIBRARY
Perrino A, Cohen I, Levin F, Luther M, Ruskin K. A942 AN ON-LINE DIGITAL ECHOCARDIOGRAPHY LIBRARY. Anesthesiology 1997, 87: 942a. DOI: 10.1097/00000542-199709001-00942.Peer-Reviewed Original Research
1996
Alterations of Cardiovascular Performance During Laparoscopic Colectomy: A Combined Hemodynamic and Echocardiographic Analysis
Harris S, Ballantyne G, Luther M, Perrino A. Alterations of Cardiovascular Performance During Laparoscopic Colectomy: A Combined Hemodynamic and Echocardiographic Analysis. Anesthesia & Analgesia 1996, 83: 482. DOI: 10.1213/00000539-199609000-00007.Peer-Reviewed Original ResearchConceptsSystemic vascular resistanceEjection fraction areaCardiac indexLaparoscopic colectomyCardiovascular performanceCardiopulmonary diseasePulmonary capillary wedge pressureCapillary wedge pressurePulmonary artery catheterEnd-diastolic areaSignificant increaseHyperdynamic stateVascular resistanceWedge pressureArtery catheterPeritoneal insufflationVentricular preloadTrendelenburg positioningGeneral anesthesiaTransesophageal echocardiographyEchocardiographic analysisEchocardiographic dataIntraoperative maneuversHemodynamic responseHeart rateAlterations of Cardiovascular Performance During Laparoscopic Colectomy
Harris S, Ballantyne G, Luther M, Perrino A. Alterations of Cardiovascular Performance During Laparoscopic Colectomy. Anesthesia & Analgesia 1996, 83: 482-487.. PMID: 8780267, DOI: 10.1097/00000539-199609000-00007.Peer-Reviewed Original ResearchConceptsEjection fraction areaSystemic vascular resistanceCoexisting cardiopulmonary diseaseCardiac indexLaparoscopic colectomyCardiovascular performancePulmonary capillary wedge pressureCardiopulmonary diseaseEnd-diastolic areaCapillary wedge pressurePulmonary artery catheterTransesophageal echocardiographyIntraoperative maneuversWedge pressurePeritoneal insufflationEchocardiographic dataVentricular preloadHyperdynamic stateArtery catheterVascular resistanceHemodynamic monitoringGeneral anesthesiaColectomyInsufflationTrendelenburgAutomated Echocardiographic Analysis
PERRINO A, LUTHER M, O'CONNOR T, COHEN I. Automated Echocardiographic Analysis. Survey Of Anesthesiology 1996, 40: 253-254. DOI: 10.1097/00132586-199608000-00061.Peer-Reviewed Original ResearchA multimedia perioperative record keeper for clinical research
Perrino A, Luther M, Phillips D, Levin F. A multimedia perioperative record keeper for clinical research. Journal Of Clinical Monitoring 1996, 12: 251-259. PMID: 8823650, DOI: 10.1007/bf00857647.Peer-Reviewed Original ResearchConceptsSoftware development toolsMultimedia dataDevelopment toolsPaper-based chartsStandard hardware componentsData analysis environmentDevelopment processExternal data sourcesData acquisition applicationsCustom software applicationReal-time acquisitionAdvanced data analysisMultimedia databasesData acquisition hardwareDatabase applicationsRelational databaseSoftware applicationsHardware interfaceNumerous usersHardware componentsAnalysis environmentPentium PCAnalysis applicationsLine accessAcquisition hardware
1994
Automated Border Detection
Perrino A, Luther M, O'Connor T, Cohen I. Automated Border Detection. Anesthesiology 1994, 81: a523. DOI: 10.1097/00000542-199409001-00522.Peer-Reviewed Original Research
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