2025
Perioperative management of patients taking glucagon-like peptide 1 receptor agonists: Society for Perioperative Assessment and Quality Improvement (SPAQI) multidisciplinary consensus statement
Oprea A, Ostapenko L, Sweitzer B, Selzer A, Irizarry-Alvarado J, Hurtado Andrade M, Mendez C, Kelley K, Stewart E, Fernandez Robles C, Chadha R, Camilleri M, Mathur R, Umpierrez G, Hepner D. Perioperative management of patients taking glucagon-like peptide 1 receptor agonists: Society for Perioperative Assessment and Quality Improvement (SPAQI) multidisciplinary consensus statement. British Journal Of Anaesthesia 2025, 135: 48-78. PMID: 40379536, DOI: 10.1016/j.bja.2025.04.001.Peer-Reviewed Original ResearchConceptsGlucagon-like peptide 1 receptor agonistsPeptide 1 receptor agonistsPerioperative management of patientsMultidisciplinary consensus statementManagement of patientsSociety for Perioperative AssessmentPerioperative managementPerioperative assessmentConsensus statementPreoperative fasting timeMedical managementAgonistsModified Delphi processPatientsSystematic reviewPREOPERATIVE GLUCAGON-LIKE PEPTIDE 1 RECEPTOR AGONISTS ASSOCIATED WITH IMPROVED POSTOPERATIVE CARDIOVASCULAR OUTCOMES
Choi U, Oprea A, Sweitzer B, Connors J, Hepner D. PREOPERATIVE GLUCAGON-LIKE PEPTIDE 1 RECEPTOR AGONISTS ASSOCIATED WITH IMPROVED POSTOPERATIVE CARDIOVASCULAR OUTCOMES. Journal Of The American College Of Cardiology 2025, 85: 517. DOI: 10.1016/s0735-1097(25)01001-0.Peer-Reviewed Original ResearchPerioperative Anticoagulation: Considerations Impacting Outcomes
Kumar M, Oprea A. Perioperative Anticoagulation: Considerations Impacting Outcomes. International Anesthesiology Clinics 2025, 63: 44-53. PMID: 40065649, DOI: 10.1097/aia.0000000000000474.Peer-Reviewed Original ResearchControversies in Perioperative Medication Management
Cummings K, Keshock M, Oprea A. Controversies in Perioperative Medication Management. International Anesthesiology Clinics 2025, 63: 35-43. PMID: 39831629, DOI: 10.1097/aia.0000000000000470.Peer-Reviewed Original ResearchPerioperative Atrial Fibrillation and Anticoagulation Management
Tao J, Oprea A. Perioperative Atrial Fibrillation and Anticoagulation Management. 2025, 148-161. DOI: 10.1093/med/9780190902001.003.0013.Peer-Reviewed Original ResearchRisk of thrombosisAbstract Atrial fibrillationOral anticoagulantsPreoperative evaluation of surgical patientsCerebral vascular accidentClasses of oral anticoagulantsPatient's risk of thrombosisRisk of surgical bleedingEvaluation of surgical patientsVitamin K antagonistsPerioperative anticoagulation managementK antagonistsSurgical bleedingPreoperative evaluationAnticoagulation managementAtrial fibrillationSurgical patientsCardiac arrhythmiasPatient riskPatientsVascular accidentAnticoagulationRiskPheochromocytoma and MEN Syndromes
Carr Z, Farela A, Oprea A. Pheochromocytoma and MEN Syndromes. 2025, 333-342. DOI: 10.1093/med/9780190902001.003.0030.Peer-Reviewed Original ResearchMultiple endocrine neoplasiaInadequate surgical resectionManagement of PPGLsRare neuroendocrine tumorsDefinitive surgical managementResection of pheochromocytomaPreoperative medical managementDiligent postoperative careHigh-risk procedurePersistent vasoplegiaResected patientsSurgical resectionNeuroendocrine tumorsPostoperative bleedingRefractory hypertensionVasopressor supportHypertensive crisisPreoperative optimizationEndocrine neoplasiaABSTRACT PheochromocytomaPostoperative periodPerioperative considerationsVentricular dysrhythmiasAnesthesia techniquesPotential complications
2024
Perioperative Management of Patients Taking Glucagon-like Peptide-1 Receptor Agonists: Applying Evidence to Clinical Practice
Oprea A, Umpierrez G, Sweitzer B, Hepner D. Perioperative Management of Patients Taking Glucagon-like Peptide-1 Receptor Agonists: Applying Evidence to Clinical Practice. Anesthesiology 2024, 141: 1141-1161. PMID: 39471345, DOI: 10.1097/aln.0000000000005204.Peer-Reviewed Original ResearchPerioperative Management of Adult Patients with Diabetes Wearing Devices: A Society for Perioperative Assessment and Quality Improvement (SPAQI) Expert Consensus Statement
Oprea A, Kalra S, Duggan E, Russell L, Urman R, Abdelmalak B, Patel P, Pfeifer K, Grant P, Charitou M, Mendez C, Sherr J, Umpierrez G, Klonoff D. Perioperative Management of Adult Patients with Diabetes Wearing Devices: A Society for Perioperative Assessment and Quality Improvement (SPAQI) Expert Consensus Statement. Journal Of Clinical Anesthesia 2024, 99: 111627. PMID: 39388833, DOI: 10.1016/j.jclinane.2024.111627.Peer-Reviewed Original ResearchPreoperative management of medications for psychiatric disorders.
Fernandez Robles C, Fernandez-Robles C, Oprea A. Preoperative management of medications for psychiatric disorders. Panminerva Medica 2024, 66: 281-292. PMID: 38757800, DOI: 10.23736/s0031-0808.24.05151-6.Peer-Reviewed Original Research
2022
Preoperative Management of Cardiovascular Medications: A Society for Perioperative Assessment and Quality Improvement (SPAQI) Consensus Statement
Sahai SK, Balonov K, Bentov N, Bierle DMM, Browning LM, Cummings KC, Dougan BM, Maxwell M, Merli GJ, Oprea AD, Sweitzer B, Mauck KF, Urman RD. Preoperative Management of Cardiovascular Medications: A Society for Perioperative Assessment and Quality Improvement (SPAQI) Consensus Statement. Mayo Clinic Proceedings 2022, 97: 1734-1751. PMID: 36058586, DOI: 10.1016/j.mayocp.2022.03.039.Peer-Reviewed Original ResearchConceptsCardiovascular medicationsPerioperative assessmentAntiarrhythmic agentsReceptor antagonistAngiotensin receptor neprilysin inhibitorQuality Improvement (SPAQI) Consensus StatementAngiotensin II receptor blockersClass I antiarrhythmic agentsClass III antiarrhythmic agentII receptor blockersClasses of medicationsEndothelin receptor antagonistsPotassium-sparing diureticsCalcium channel blockersÎ’-adrenoceptor blockersAdrenergic receptor antagonistPhosphodiesterase-5 inhibitorsEvidence-based recommendationsSodium channel blockersPotassium channel openersSympatholytic medicationsReceptor blockersPerioperative managementHeart failureLoop diureticsPreoperative Management of Medications for Rheumatologic and HIV Diseases: Society for Perioperative Assessment and Quality Improvement (SPAQI) Consensus Statement
Russell LA, Craig C, Flores EK, Wainaina JN, Keshock M, Kasten MJ, Hepner DL, Edwards AF, Urman RD, Mauck KF, Oprea AD. Preoperative Management of Medications for Rheumatologic and HIV Diseases: Society for Perioperative Assessment and Quality Improvement (SPAQI) Consensus Statement. Mayo Clinic Proceedings 2022, 97: 1551-1571. PMID: 35933139, DOI: 10.1016/j.mayocp.2022.05.002.Peer-Reviewed Original ResearchConceptsPerioperative medication managementPerioperative assessmentConsensus statementPreoperative managementMedication managementQuality Improvement (SPAQI) Consensus StatementEvidence-based perioperative careAnti-inflammatory medicationsPerioperative medical managementInfectious disease specialistsLong-term medicationInternal medicine physiciansComplexity of patientsPreoperative optimizationHIV diseaseCommon medicationsPerioperative careMedical managementDisease specialistsClinical guidanceConsensus recommendationsSurgical proceduresMedicine physiciansMedicationsExpert consensusPostdural Puncture Headache—Risks and Current Treatment
Li H, Wang Y, Oprea AD, Li J. Postdural Puncture Headache—Risks and Current Treatment. Current Pain And Headache Reports 2022, 26: 441-452. PMID: 35353358, DOI: 10.1007/s11916-022-01041-x.Peer-Reviewed Original ResearchConceptsPostdural puncture headacheCurrent treatmentDevelopment of PDPHMild postdural puncture headacheSevere postdural puncture headacheSelf-limited headacheEpidural blood patchFirst-line treatmentLong-term complicationsTherapy of choiceDull achingHeadache riskPDPH patientsPharmacological managementConservative treatmentBlood patchConservative managementFrequent complicationNerve blockNeuraxial blockNeuraxial techniquesPuncture headacheBed restChronic headacheFemale sexPerioperative Management of Patients with Idiopathic Pulmonary Fibrosis Undergoing Noncardiac Surgery: A Narrative Review
Carr ZJ, Yan L, Chavez-Duarte J, Zafar J, Oprea A. Perioperative Management of Patients with Idiopathic Pulmonary Fibrosis Undergoing Noncardiac Surgery: A Narrative Review. International Journal Of General Medicine 2022, 15: 2087-2100. PMID: 35237071, PMCID: PMC8882471, DOI: 10.2147/ijgm.s266217.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsIdiopathic pulmonary fibrosisInterstitial lung diseaseIdiopathic interstitial pneumoniaIPF patientsNarrative reviewPerioperative managementHome oxygen useSafe perioperative carePostoperative pulmonary complicationsRetrospective cohort studyCardiopulmonary exercise testingOptimal perioperative managementPreoperative risk stratificationPulmonary function studiesWeb of ScienceAcute exacerbationARISCAT scorePostoperative pneumoniaPulmonary complicationsNoncardiac surgerySurgical populationCohort studyExercise testingInterstitial pneumoniaNeuraxial anesthesiaPreoperative Management of Medications for Neurologic Diseases Society for Perioperative Assessment and Quality Improvement Consensus Statement
Oprea AD, Keshock MC, O'Glasser AY, Cummings KC, Edwards AF, Hunderfund AL, Urman RD, Mauck KF. Preoperative Management of Medications for Neurologic Diseases Society for Perioperative Assessment and Quality Improvement Consensus Statement. Mayo Clinic Proceedings 2022, 97: 375-396. PMID: 35120701, DOI: 10.1016/j.mayocp.2021.11.010.Peer-Reviewed Original ResearchConceptsPreoperative managementPerioperative assessmentNeurologic disordersQuality Improvement (SPAQI) Consensus StatementEvidence-based recommendationsPerioperative medicationsDiseases SocietyPerioperative cliniciansSocietal guidelinesConsensus statementNeurologic diseaseConsensus recommendationsInvasive proceduresMedicationsDrug substitutionIndividualized approachAnesthesia practicePerioperative medicineInternal medicineDisordersPatientsLaboratory testingMedicineManagementCliniciansPreoperative Management of Medications for Psychiatric Diseases Society for Perioperative Assessment and Quality Improvement Consensus Statement
Oprea AD, Keshock MC, O'Glasser AY, Cummings KC, Edwards AF, Zimbrean PC, Urman RD, Mauck KF. Preoperative Management of Medications for Psychiatric Diseases Society for Perioperative Assessment and Quality Improvement Consensus Statement. Mayo Clinic Proceedings 2022, 97: 397-416. PMID: 35120702, DOI: 10.1016/j.mayocp.2021.11.011.Peer-Reviewed Original ResearchConceptsPsychiatric medication managementPreoperative managementPerioperative assessmentMedication managementConsensus statementQuality Improvement (SPAQI) Consensus StatementAttention deficit hyperactivity disorder medicationsDay of surgeryRisk of relapseHyperactivity disorder medicationsCategories of drugsMedication classesPerioperative complicationsDiseases SocietyMost medicationsIndividual medicationsMood stabilizersPsychiatric medicationsConsensus recommendationsMedicationsDrug categoriesCertain drugsPatient carePsychiatric conditionsProcedure cancellations23 Hematologic disorders
Oprea A. 23 Hematologic disorders. 2022, 465-496. DOI: 10.1016/b978-0-323-71860-8.00032-x.Peer-Reviewed Original Research
2021
Perioperative thrombocytopenia
Lombard FW, Popescu WM, Oprea AD, Kertai MD. Perioperative thrombocytopenia. Current Opinion In Anaesthesiology 2021, 34: 335-344. PMID: 33935182, DOI: 10.1097/aco.0000000000000999.Peer-Reviewed Original ResearchConceptsPlatelet countThrombopoietin receptor agonistsRisk of bleedingProphylactic platelet transfusionsProthrombin complex concentrateRecombinant factor VIIGood quality evidenceThreshold platelet countIntravenous immunoglobulinPreoperative thrombocytopeniaAsymptomatic patientsPerioperative strategiesPerioperative managementSevere bleedingAntifibrinolytic agentsPlatelet transfusionsComplex concentrateQuality evidenceFibrinogen levelsReceptor agonistPerioperative thrombocytopeniaPlatelet functionThrombin generationIntraoperative alternativeFactor VIIEditorial: Perioperative medicine: a bridge (not) too far!
Oprea AD. Editorial: Perioperative medicine: a bridge (not) too far! Current Opinion In Anaesthesiology 2021, 34: 306-308. PMID: 33935178, DOI: 10.1097/aco.0000000000000995.Peer-Reviewed Original ResearchEndocrine emergencies in anesthesia
Fernandez-Robles C, Carr ZJ, Oprea AD. Endocrine emergencies in anesthesia. Current Opinion In Anaesthesiology 2021, 34: 326-334. PMID: 33935181, DOI: 10.1097/aco.0000000000000986.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsEndocrine disordersPerioperative managementOral hyperglycemic agentsPerioperative fluid resuscitationPerioperative glycemic managementSafe perioperative managementCommon endocrine disorderPerioperative time periodNumber of patientsBetter operative outcomesInvasive surgical techniquesCarcinoid syndromeEndocrine emergencyAdverse eventsFluid resuscitationGlycemic managementOperative outcomesAvoidable complicationsMedical managementComplex patientsSurgical techniqueHyperglycemic agentOptimal managementOperating roomDisordersThe Electrophysiology Laboratory: Anesthetic Considerations and Staffing Models
Siegrist KK, Fernandez Robles C, Kertai MD, Oprea AD. The Electrophysiology Laboratory: Anesthetic Considerations and Staffing Models. Journal Of Cardiothoracic And Vascular Anesthesia 2021, 35: 2775-2783. PMID: 33773891, DOI: 10.1053/j.jvca.2021.02.050.Peer-Reviewed Original Research
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