My research in the Ehrlich lab focuses on calcium signaling that occurs within a specialized subcellular domain known as the mitochondria-associated endoplasmic reticulum membrane (MAM). In particular, I study how calcium signaling alterations in this region arise in hepatocytes as a result of hepatic steatosis and metabolic dysfunction. I became interested in metabolic pathologies caused from over-nutrition during my time at UW-Madison, where I studied high fat diet-induced type 2 diabetes. As a consequence, much of my studies seek to elucidate both normal and pathological mechanisms of MAM signaling, as well as the consequences of steatosis on the calcium channels found in this domain.
Education & Training
- BSUniversity of Wisconsin-Madison (2013)