Use of transgenic mice in acid-base balance studies.
Cantone A, Wang T, Pica A, Simeoni M, Capasso G. Use of transgenic mice in acid-base balance studies. Journal Of Nephrology 2006, 19 Suppl 9: s121-7. PMID: 16736435.Peer-Reviewed Original ResearchMeSH KeywordsAcid-Base EquilibriumAcid-Base ImbalanceAnimalsCation Transport ProteinsDisease Models, AnimalDNAGene ExpressionKidney TubulesMembrane ProteinsMiceMice, TransgenicNitric Oxide SynthaseSodium-Bicarbonate SymportersSodium-Hydrogen Exchanger 1Sodium-Hydrogen Exchanger 3Sodium-Hydrogen ExchangersConceptsAcid-base statusNitric oxide synthaseTransgenic miceMedullary thick ascending limbProximal tubule transportThick ascending limbSubunit expression levelsPotassium-chloride cotransporterKnockout animal modelsAcid-base balanceKidney regulationTransepithelial HCO3- absorptionNatriuretic responseBlood pressureRenal diseaseOxide synthaseDistal nephronAnimal modelsEndothelial isoformTubule transportBasolateral NHE1Proximal tubulesFunction of pendrinAscending limbHCO3- absorption