Effect of hypoxia and hypercapnia on ACE activity in the cerebral microcirculation of anesthetized dogs
Pitt B, Lister G, Dawson C, Linehan J. Effect of hypoxia and hypercapnia on ACE activity in the cerebral microcirculation of anesthetized dogs. American Journal Of Physiology 1986, 250: h806-h814. PMID: 3010743, DOI: 10.1152/ajpheart.1986.250.5.h806.Peer-Reviewed Original ResearchConceptsBPAP metabolismACE activityCerebral microcirculationAnesthetized dogsCerebral blood flowCommon carotid arteryEffects of hypoxiaSynthetic ACE substrateCerebral capillariesBolus injectionLateral sinusSagittal sinusCarotid arteryBlood flowBone waxBlood samplesLack of changeHypercapniaVenous outflow curvesHypoxiaPerfusion heterogeneityACE substrateOutflow curvesSinusMicrocirculation