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Ane Landajuela Larma

she/her/hers
Associate Research Scientist

Contact Information

Ane Landajuela Larma

Lab Location

Mailing Address

  • Associate Research Scientists

    Nanobiology Institute, Yale University 850 West Campus Drive, ISTC 220

    West Haven, CT 06516

    United States

Biography

I am biochemist with a background in the study of the dynamics of cellular membranes. I earned my Biochemistry degree from the University of the Basque Country (UPV/EHU) and completed my Ph.D. at the BIOFISIKA Institute (UPV/EHU, CSIC), where my research focused on the mode of action of apoptosis-related BCL-2 family proteins. During a brief postdoctoral stay at the same institute, I explored membrane fusion facilitated by the autophagic LC3 conjugation system.

Currently, I work as an Associate Research Scientist at Yale University in Erdem Karatekin's laboratory. I focus on investigating membrane fusion, fission, and membrane flows at both molecular and cellular levels with the broad goal of understanding how these processes influence one another and are linked to higher physiological functions. Recently I have contributed to the understanding of the mechanism underlying membrane fission during sporulation in Bacillus subtilis, revealing a previously unappreciated second function of DNA translocation in energizing the process under energy-limited conditions. In future studies, I aim to explore how lipids and other components are transported across the membrane compartments that form during sporulation.

Education & Training

  • Invited Researcher
    Université Paris Cité (2023)
  • Invited Researcher
    Gustave Roussy Cancer Campus (2023)
  • Postdoctoral Associate
    Yale University (2020)
  • Teaching Fellow
    Yale University (2018)
  • Postdoctoral Associate
    Biophysics Unit, University of the Basque Country UPV/EHU-CSIC (2016)
  • PhD
    Biophysics Unit, University of the Basque Country UPV/EHU-CSIC (2016), Biochemistry Department. (2013)
  • Basque Government Doctoral Fellow
    Biophysics Unit, University of the Basque Country UPV/EHU-CSIC (2013)
  • MSc
    Faculty of Science and Technology. University of the Basque Country UPV/EHU, Molecular Biology and Biomedicine (2009)
  • BSc
    Faculty of Science and Technology. University of the Basque Country UPV/EHU, Biochemistry (2008)

Activities

  • Membrane fission during bacterial spore development requires cellular inflation driven by DNA translocation
    Philadelphia, PA, United States 2024
    The Biophysical Society Annual Meeting
  • Membrane fission during bacterial spore development requires cellular inflation driven by DNA translocation
    San Francisco, CA, United States 2022
    Biophysical Society 66th Annual Meeting
  • FisB relies on homo-oligomerization and lipid binding to catalyze membrane fission in bacteria_
    San Diego, CA, United States 2020
    Biophysical Society 64th Annual Meeting

Professional Service

OrganizationRoleDate
Universidad de São PauloThesis Committee Member2023 - 2025
New Haven Public SchoolsMentor2023
Yale Working Women NetworkMentor2023
Yale Postdoctoral AssociationCommittee Member2019 - 2020