Genetics Clinical Grand Rounds: "The face predicts the brain: is this still valid in the genomic era?"

Program Objective(s):

1. Cerebral and craniofacial malformations seen in patient’s with holoprosencephaly and frontonasal dysplasia conditions

2. Review the genetics and genotype phenotype correlation in holoprosencephaly

3. ZIC2 gene pleiotropy from embryogenesis to carcinogenesis