2025
Functional Correlates of Atypical Visuoperceptual Organization in a Multisite Clinical High-Risk Sample
Pokorny V, Tran T, Williams T, Kenney J, Silverstein S, Gold J, Waltz J, Schiffman J, Ellman L, Strauss G, Walker E, Woods S, Powers A, Corlett P, Mittal V. Functional Correlates of Atypical Visuoperceptual Organization in a Multisite Clinical High-Risk Sample. Journal Of Psychopathology And Clinical Science 2025, 134: 527-539. PMID: 40193439, PMCID: PMC12162206, DOI: 10.1037/abn0000992.Peer-Reviewed Original ResearchConceptsClinical high riskPsychotic-like Experiences groupClinical high-risk statusClinical high-risk samplesMeasures of cognitive abilityClinical high-risk groupHigh-risk sampleMeasuring perceptual organizationFaces taskPsychotic disordersPerceptual priorsCognitive abilitiesCognitive functionClinical groupsPerceptual organizationHealthy control groupContext-sensitiveSocial functioningTwo-tone imagesTarget circleSymbolic codeEbbinghausFunctional correlatesTaskParticipantsTiming of repeat epinephrine to inform paediatric anaphylaxis observation periods: a retrospective cohort study
Dribin T, Sampson H, Zhang Y, Boyd S, Zhang N, Michelson K, Neuman M, Brousseau D, Mistry R, Freedman S, Aronson P, Bergmann K, Boswell B, Chinta S, Chua W, Cohen A, Cohen J, Daggett A, Davis J, Freeman J, Khanna K, Knoles C, Kwan K, Larsen C, Lee J, Lubell T, Metcalf A, Moake M, Nesiama J, Ngo T, Pulcini C, Russo C, Singh N, Srivastava G, Strutt J, Thapar V, Vander Wyst C, Walsh P, Wolnerman Y, Schnadower D, Academy of Pediatrics P, Kanngiesser A, McGarghan F, Dulchavsky A, Costalez J, DesPain A, Armanious M, Haghnazarian E, Brown-Whitehorn T, Weigert R, Dayan P, Meltzer J, Chowdhury N, Benedetti J, Sinziana C, Handorf A, Ruthford M, Devens M, Mecham C, Holland J, Casas T, Brown J, Panda P, Morrow A, Maready M, Nathani Y, Stevens M, Abraham G, Yen K, Cooper-Sood J, Woolf S. Timing of repeat epinephrine to inform paediatric anaphylaxis observation periods: a retrospective cohort study. The Lancet Child & Adolescent Health 2025, 9: 484-496. PMID: 40506197, DOI: 10.1016/s2352-4642(25)00139-7.Peer-Reviewed Original ResearchConceptsElectronic medical recordsEmergency departmentRetrospective cohort studyCohort studyMedical recordsDocumentation of symptomsCardiovascular involvementHealth-care facilitiesEpinephrine doseAcute allergic reactionsNational Institutes of HealthCumulative incidenceNational Center for Advancing Translational SciencesInstitutes of HealthChildren aged 6 monthsClinical ModificationHospital wardsIncidence rateICD-10Observation periodPrimary outcomeAllergic reactionsSecondary to medicationsInitiation to discontinuationKaplan-Meier analysisPediatric Nonfatal Firearm Injury Health Care Utilization.
Du J, Andrews A, Gastineau K, Lee L, Ranney M, Sacks C, Song Z, Fleegler E, Pulcini C. Pediatric Nonfatal Firearm Injury Health Care Utilization. 2025, 156 PMID: 40555422, DOI: 10.1542/peds.2024-070424.Peer-Reviewed Original ResearchConceptsFirearm injuriesHealth care outcomesHealth care useHealth care utilizationMental health diagnosesPediatric firearm injuriesHealth care spendingCare outcomesCare useInjury preventionCare utilizationPostinjury careInjured childrenHealth diagnosisCare spendingPrevention effortsHealth impactsIntervention effortsHealthLongitudinal researchChildrenPostinjuryCost-effectiveFirearmUnited StatesA Vaccine to Block Plasmodium falciparum Transmission.
Healy S, Sagara I, Assadou M, Katile A, Kone M, Imeru A, Kwan J, Swihart B, Fintzi J, Potter G, Zeguimé A, Dolo A, Diarra B, Narum D, Rausch K, MacDonald N, Zhu D, Mohan R, Thera I, Morrison R, Zaidi I, Doritchamou J, Sylla D, Hume J, Coulibaly M, Morelle D, Lievens M, Doumbo O, Duffy P. A Vaccine to Block Plasmodium falciparum Transmission. NEJM Evidence 2025, 4: evidoa2400188. PMID: 40552966, DOI: 10.1056/evidoa2400188.Peer-Reviewed Original ResearchConceptsStandard membrane feeding assayPfs230D1-EPASafety trialsAntibody responseEnd pointsSkin feeding assaysTransmission-reducing activityWeeks of follow-upMembrane feeding assaysAs-treated populationPrimary efficacy analysisSecondary end pointsPrimary end pointInfected mosquitoesEnzyme-linked immunosorbent assayMalian adultsMalaria vaccineComparator-controlledDouble-blindProportion of infected mosquitoesDosing regimensEfficacy analysisThird doseYears postvaccinationBlock disease transmissionValidation of a food security experience scale among indigenous populations in Brazil
Segall-Corrêa A, Luz V, do Amaral Azevedo M, Ferreira B, Emperaire L, Gruppi D, Marín-Leon L, Licio J, Pérez-Escamilla R. Validation of a food security experience scale among indigenous populations in Brazil. International Journal For Equity In Health 2025, 24: 175. PMID: 40517230, PMCID: PMC12167585, DOI: 10.1186/s12939-025-02515-1.Peer-Reviewed Original ResearchConceptsSevere food insecurityFood insecurityIndigenous populationGood/very good healthPoor health statusIndigenous householdsPsychometrically valid scaleIndigenous organizationsIndigenous peoplesNutrition insecurityHealth statusRural communitiesGood healthHouseholdsBivariate analysisInsecurityNutrition securityLinguistic diversityRasch modelUrban areasIncomeMeasurement scaleExperiences ScaleMethodsA totalMitigate foodCannabis Legalization and Opioid Use Disorder in Veterans Health Administration Patients
Mannes Z, Wall M, Alschuler D, Malte C, Olfson M, Livne O, Fink D, Keyhani S, Keyes K, Martins S, Cerdá M, Sacco D, Gutkind S, Maynard C, Sherman S, Saxon A, Hasin D. Cannabis Legalization and Opioid Use Disorder in Veterans Health Administration Patients. JAMA Health Forum 2025, 6: e251369. PMID: 40512510, PMCID: PMC12166489, DOI: 10.1001/jamahealthforum.2025.1369.Peer-Reviewed Original ResearchConceptsVeterans Health AdministrationVeterans Health Administration patientsMedical cannabis lawsOpioid use disorderPrevalence of opioid use disorderClassification of DiseasesRecreational cannabis lawsChronic painVeterans Health Administration electronic health recordClinical ModificationConsistent with overall findingsState medical cannabis lawsInternational Statistical Classification of DiseasesReceipt of prescription opioidsStatistical Classification of DiseasesElectronic health recordsInternational Classification of DiseasesNon-Hispanic whitesOpioid use disorder diagnosisOpioid use disorder prevalenceInternational Statistical ClassificationDifference-in-differences analysisCannabis lawsUse disorderBurden of opioid use disorderThe Transdiagnostic Connectome Project: an open dataset for studying brain-behavior relationships in psychiatry
Chopra S, Cocuzza C, Lawhead C, Ricard J, Labache L, Patrick L, Kumar P, Rubenstein A, Moses J, Chen L, Blankenbaker C, Gillis B, Germine L, Harpaz-Rotem I, Yeo B, Baker J, Holmes A. The Transdiagnostic Connectome Project: an open dataset for studying brain-behavior relationships in psychiatry. Scientific Data 2025, 12: 923. PMID: 40456751, PMCID: PMC12130183, DOI: 10.1038/s41597-025-04895-z.Peer-Reviewed Original ResearchConceptsTask-based functional MRIHigh-resolution anatomical scansBrain-behavior relationshipsHealthy comparison groupFeatures of brain functionFunctional network organizationClinically relevant symptomsPsychiatric illnessFunctional MRINeuroimaging dataResting-stateBrain functionClinical neuroscienceCognitive AssessmentBehavioral dataConnectome ProjectAnatomical scansComparison groupDiagnostic criteriaNetwork organizationRelevant symptomsPsychiatryActivating effectIndividualsTransdiagnosticSoil‐Transmitted Helminths and the Intricacies of Immunoregulation: Evidence From Amazonian Ecuador for the Importance of Considering Species‐Specific Effects Within the Old Friends Hypothesis
Cepon‐Robins T, Gildner T, Urlacher S, Liebert M, Madimenos F, Bribiescas R, Eick G, Harrington C, Sugiyama L, Snodgrass J. Soil‐Transmitted Helminths and the Intricacies of Immunoregulation: Evidence From Amazonian Ecuador for the Importance of Considering Species‐Specific Effects Within the Old Friends Hypothesis. American Journal Of Human Biology 2025, 37: e70076. PMID: 40444920, PMCID: PMC12175971, DOI: 10.1002/ajhb.70076.Peer-Reviewed Original ResearchConceptsSystemic inflammationImmune biomarkersIL-6Infection statusSpecies-specific relationshipsOld Friends hypothesesSpecies-specific effectsExacerbated systemic inflammationSoil-Transmitted HelminthsFinger-prick blood samplesLevels of CRPLow CRP levelsHelminth speciesCoinfected participantsAmazonian EcuadorHigh IgECRP levelsUninfected participantsPerinatal Exposures to Ambient Fine Particulate Matter and Outdoor Artificial Light at Night and Risk of Pediatric Papillary Thyroid Cancer
Deziel N, Wang R, Warren J, Dinauer C, Ogilvie J, Clark C, Zhong C, Wiemels J, Morimoto L, Metayer C, Ma X. Perinatal Exposures to Ambient Fine Particulate Matter and Outdoor Artificial Light at Night and Risk of Pediatric Papillary Thyroid Cancer. Environmental Health Perspectives 2025, 133: 057026. PMID: 40209106, PMCID: PMC12121722, DOI: 10.1289/ehp14849.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAir PollutantsCaliforniaCarcinoma, PapillaryCase-Control StudiesChildChild, PreschoolEnvironmental ExposureFemaleHumansInfantInfant, NewbornLightingMaleParticulate MatterPregnancyPrenatal Exposure Delayed EffectsRisk FactorsThyroid Cancer, PapillaryThyroid NeoplasmsYoung AdultConceptsThyroid cancer riskOutdoor artificial lightAmbient fine particulate matterCancer riskOdds ratioAge groupsConfidence intervalsExposure to ambient fine particulate matterIndividual-level exposuresAssociated with thyroid cancerPediatric thyroid cancer incidenceControls frequency-matchedPapillary thyroid cancer riskThyroid cancer incidenceFine particulate matterCalifornia birth cohortOutdoor air pollutionAerodynamic diameter <Case-control studyHypothesized risk factorsStatistically significant associationCancer incidenceThyroid cancerExposure tertilesFrequency-matchedNational Trends in Suicidal Thoughts and Suicide Attempts Among High School Students in the United States
Bommersbach T, Olfson M, Rhee T. National Trends in Suicidal Thoughts and Suicide Attempts Among High School Students in the United States. American Journal Of Psychiatry 2025, 182: 639-659. PMID: 40432341, DOI: 10.1176/appi.ajp.20240706.Peer-Reviewed Original ResearchConceptsPast-year suicidal thoughtsSuicidal thoughtsHigh school studentsHealth risk behaviorsSuicidal symptomsSuicide attemptsNon-Hispanic whitesSchool studentsBehavioral risksBlack studentsNational trendsHigh school seniorsU.S. high school studentsDepressive symptomsAttempted suicideRisk categoriesEstimate national trendsBiennial cross-sectional surveysMultivariate logistic regressionSuicideYouth Risk Behavior SurveySchool seniorsElevated ratesHealth risk categoriesRisk Behavior SurveyFunctional connectome-based predictive modeling of suicidal ideation
Averill L, Tamman A, Fouda S, Averill C, Nemati S, Ragnhildstveit A, Gosnell S, Akiki T, Salas R, Abdallah C. Functional connectome-based predictive modeling of suicidal ideation. Journal Of Affective Disorders 2025, 387: 119518. PMID: 40441623, DOI: 10.1016/j.jad.2025.119518.Peer-Reviewed Original ResearchConceptsSuicidal ideationAssociated with increased suicidal ideationRecurrent major depressive disorderConnectome-based predictive modelingResting-state functional magnetic resonance imagingMechanisms of suicidal behaviorAssociated with suicidal ideationFunctional magnetic resonance imagingMajor depressive disorderDorsal salience networkIncreased suicidal ideationIncreased network integrationIncreased suicide riskThe Menninger ClinicNetwork integrationReduced network integrationRelative to controlsCentral executiveDepressive disorderDepressive episodeSalience networkNeural alterationsSuicidal behaviorSuicide riskBrain networksThe Eating Disorders Genetics Initiative 2 (EDGI2): study protocol
Berthold N, MacDermod C, Thornton L, Parker R, Morales S, Hog L, Kennedy H, Guintivano J, Sullivan P, Crowley J, Johnson J, Birgegård A, Fundín B, Frans E, Xu J, “Ngāti Pūkenga” M, Miller A, Aguilar M, Barakat S, Abdulkadir M, White J, Larsen J, Trujillo E, Winterman B, Zhang R, Lawson R, Wonderlich S, Wonderlich J, Schaefer L, Mehler P, Oakes J, Foster M, Gaudiani J, Vacuán E, Compte E, Petersen L, Yilmaz Z, Micali N, Jordan J, Kennedy M, Maguire S, Huckins L, Lu Y, Dinkler L, Martin N, Bulik C. The Eating Disorders Genetics Initiative 2 (EDGI2): study protocol. BMC Psychiatry 2025, 25: 532. PMID: 40419993, PMCID: PMC12105188, DOI: 10.1186/s12888-025-06777-5.Peer-Reviewed Original ResearchConceptsPolygenic risk scoresAvoidant/restrictive food intake disorderCalculate polygenic risk scoresNational Patient RegisterPsychiatric Genomics ConsortiumEating disordersLongstanding illnessEating Disorders Working GroupUnited StatesPatient RegisterCase-controlNew ZealandCase identificationGenetic architectureEvaluate clinical outcomesFood intake disorderRisk scoreClinically relevant phenotypesStudy protocolQuestionnaire batteryFunctional biologySymptom levelsAncestral backgroundMetabolic traitsGenomics ConsortiumCost-effective pricing of long-acting injectable HIV pre-exposure prophylaxis for adolescent girls and young women in South Africa: a model-based analysis
Jin E, Ahmed A, Bekker L, Rousseau E, Dugdale C, Flanagan C, Wallace M, Freedberg K, Orrell C, Reddy K, Paltiel A, Ciaranello A, Neilan A. Cost-effective pricing of long-acting injectable HIV pre-exposure prophylaxis for adolescent girls and young women in South Africa: a model-based analysis. The Lancet Global Health 2025, 13: e1230-e1239. PMID: 40441175, DOI: 10.1016/s2214-109x(25)00119-6.Peer-Reviewed Original ResearchConceptsHIV pre-exposure prophylaxisPre-exposure prophylaxisLife yearsIncremental cost-effectiveness ratioTDF-FTCCAB-LAAdolescent girlsYoung womenHIV-related careHealth-care sector perspectiveDaily oral tenofovir disoproxil fumarateIncrease life-yearsDaily oral TDF-FTCOral tenofovir disoproxil fumaratePrEP programmesCumulative HIV-transmissionHIV incidencePrEP persistenceTenofovir disoproxil fumarateCost-effectiveness ratioHIV transmissionCost-effectiveModel-projected outcomesSouth AfricaPrEP drugsInvestigating the familiality of trichotillomania and excoriation disorder
Chen D, Farhat L, Lebowitz E, Silverman W, Bloch M, Fernandez T, Olfson E. Investigating the familiality of trichotillomania and excoriation disorder. Psychiatry Research 2025, 350: 116560. PMID: 40449230, PMCID: PMC12179820, DOI: 10.1016/j.psychres.2025.116560.Peer-Reviewed Original ResearchConceptsFamily history of mental health disordersFirst-degreeHistory of mental health disordersSelf-reported family historyExcoriation disorderFamily history of individualsMental health historyMental health disordersFamily history of anxietyHistory of anxietyCross-sectional survey responsesFirst-degree relativesHealth historyHealth disordersFamily historySurvey responsesAged 4Etiological underpinningsTrichotillomaniaAnxietyDepressionIndividualsHistory of individualsDisordersEnvironmental factorsSocio‐ecological domains and adolescent mental health: An application of the dual‐factor model
Rose T, Lambert S, Liu C, Raghunathan R, Musci R, Sullivan A, Lyall K, Elliott A, McEvoy C, Frazier J, Shipp G, Koinis‐Mitchell D, Ganiban J, Smith P, Newby L, Adair L, Jacobson L, Catellier D, McGrath M, Douglas C, Duggal P, Knapp E, Kress A, Blackwell C, Mansolf M, Lai J, Ho E, Cella D, Gershon R, Macy M, Das S, Freedman J, Mallal S, McLean J, Shah R, Shilts M, Alshawabkeh A, Cordero J, Meeker J, Trasande L, Camargo C, Hasegawa K, Zhu Z, Sullivan A, Dabelea D, Perng W, Bekelman T, Wilkening G, Magzamen S, Moore B, Starling A, Rinehart D, Mitchell D, D’Sa V, Deoni S, Mueller H, Duarte C, Monk C, Canino G, Posner J, Murray T, Lugo‐Candelas C, Dunlop A, Brennan P, Hockett C, Elliott A, Ferrara A, Croen L, Hedderson M, Ainsworth J, Bacharier L, Bendixsen C, Gern J, Gold D, Hartert T, Jackson D, Johnson C, Joseph C, Kattan M, Hershey G, Lemanske R, Lynch S, Miller R, O’Connor G, Ober C, Ownby D, Rivera‐Spoljaric K, Ryan P, Seroogy C, Singh A, Wood R, Zoratti E, Habre R, Farzan S, Gilliland F, Hertz‐Picciotto I, Bennett D, Schweitzer J, Schmidt R, LaSalle J, Hipwell A, Karr C, Bush N, LeWinn K, Sathyanarayana S, Zhao Q, Tylavsky F, Carroll K, Loftus C, Leve L, Ganiban J, Neiderhiser J, Weiss S, Litonjua A, McEvoy C, Spindel E, Tepper R, Newschaffer C, Lyall K, Volk H, Landa R, Ozonoff S, Piven J, Hazlett H, Pandey J, Schultz R, Dager S, Botteron K, Messinger D, Stone W, Ames J, O’Connor T, Miller R, Oken E, Hacker M, James‐Todd T, O’Shea T, Fry R, Frazier J, Singh R, Rollins C, Montgomery A, Vaidya R, Joseph R, Washburn L, Gogcu S, Bear K, Rollins J, Hooper S, Taylor G, Jackson W, Thompson A, Daniels J, Hernandez M, Lu K, Msall M, Lenski M, Obeid R, Pastyrnak S, Jensen E, Sakai C, Santos H, Kerver J, Paneth N, Barone C, Elliott M, Ruden D, Fussman C, Herbstman J, Margolis A, Schantz S, Geiger S, Aguiar A, Tabb K, Strakovsky R, Woodruff T, Morello‐Frosch R, Padula A, Stanford J, Porucznik C, Giardino A, Wright R, Wright R, Collett B, Baumann‐Blackmore N, Gangnon R, Jackson D, McKennan C, Wilson J, Altman M, Aschner J, Stroustrup A, Merhar S, Moore P, Pryhuber G, Hudak M, Lyndaker A, Lampland A, Rochelson B, Jan S, Blitz M, Katzow M, Brown Z, Chiuzan C, Rafael T, Lewis D, Meirowitz N, Poindexter B, Gebretsadik T, Osmundson S, Straughen J, Eapen A, Cassidy‐Bushrow A, Wegienka G, Sitarik A, Woodcroft K, Urquhart A, Levin A, Johnson‐Hooper T, Davidson B, Ma T, Barrett E, Blaser M, Dominguez‐Bello M, Horton D, Jimenez M, Rosen T, Palomares K, Avalos L, Zhu Y, Hunt K, Newman R, Bloom M, Alkis M, Roberts J, Mumford S, Burris H, DeMauro S, Yee L, Hamvas A, Olidipo A, Haddad A, Eiland L, Spillane N, Suri K, Fisher S, Goldstein J, Mithal L, DeRegnier R, Maitre N, Nguyen R, JaKa M, Sidebottom A, Paidas M, Potter J, Ruby N, Duthely L, Jayakumar A, Young K, Maldonado I, Miller M, Slaughter J, Keim S, Lynch C, Venkatesh K, Whitworth K, Symanski E, Northrup T, Mendez‐Figueroa H, Mosquera R, Karagas M, Madan J, MacKenzie D, Lewis J, Rennie B, Leventhal B, Kim Y, Bishop S, Nozadi S, Luo L, Lester B, Marsit C, Everson T, Loncar C, McGowan E, Sheinkopf S, Carter B, Check J, Helderman J, Neal C, Smith L. Socio‐ecological domains and adolescent mental health: An application of the dual‐factor model. Journal Of Research On Adolescence 2025, 35: e70029. PMID: 40400085, PMCID: PMC12095899, DOI: 10.1111/jora.70029.Peer-Reviewed Original ResearchConceptsMental health groupDual-factor modelMental healthHealth groupsDual-factor model of mental healthComprehensive assessment of mental healthAssessment of mental healthModel of mental healthChild health outcomesNon-Hispanic whitesPositive mental healthLatent profile analysisLatent regression analysesNo significant moderatorsMental health profilesAdolescent mental healthSocio-ecological domainsCross-sectional dataSocioecological domainsHealth outcomesHealth profileSignificant moderatorEnvironmental influencesHealthDual factorsFeasibility of machine learning–based modeling and prediction to assess osteosarcoma outcomes
Zhao Q, Hu W, Xia Y, Dai S, Wu X, Chen J, Yuan X, Zhong T, Xi X, Wang Q. Feasibility of machine learning–based modeling and prediction to assess osteosarcoma outcomes. Scientific Reports 2025, 15: 17386. PMID: 40389469, PMCID: PMC12089500, DOI: 10.1038/s41598-025-00179-z.Peer-Reviewed Original ResearchConceptsGene signatureLow-risk score groupIncreased metastasis riskLow-risk patientsSensitive to immunotherapyUnivariate Cox regression analysisReduced immune infiltrationCox regression analysisPersonalized therapeutic strategiesAggressive bone malignancyOsteosarcoma outcomesPersonalized treatment strategiesHigh-risk scoreOverall survivalHigher mortality rateProlonged survivalMetastasis riskMulticenter cohortImmune infiltrationPoor prognosisRisk stratificationC-indexDrug sensitivityClinical managementPrognostic toolImpact of young adult life transitions on adult mental health problems: a propensity score analysis
Copeland W, Prytherch S, Rothenberg W, Godwin J, Gaydosh L, Gutin I, Tong G, Shanahan L. Impact of young adult life transitions on adult mental health problems: a propensity score analysis. Psychological Medicine 2025, 55: e152. PMID: 40384216, PMCID: PMC12094619, DOI: 10.1017/s0033291725001072.Peer-Reviewed Original ResearchConceptsMental health problemsMental health symptomsAdult life transitionsHealth symptomsYoung adults transitionAntisocial personality disorder symptomsLife transitionsAntisocial personality symptomsPersonality disorder symptomsGreat Smoky Mountains StudyAdult mental health problemsChildhood mental health problemsEarly life adversityChildhood mental health symptomsDisorder symptomsLife adversityPersonality symptomsPsychiatric symptomsEmotional symptomsAdult transitionSubstance useHealth problemsMountains StudyYoung adulthoodSymptomsThe hidden burden: self-reported irritability in adolescent girls signals higher psychiatric risk
Vidal-Ribas P, Krebs G, Silver J, Tseng W, Ford T, Stringaris A. The hidden burden: self-reported irritability in adolescent girls signals higher psychiatric risk. BMC Public Health 2025, 25: 1832. PMID: 40389896, PMCID: PMC12087224, DOI: 10.1186/s12889-025-23076-6.Peer-Reviewed Original ResearchConceptsSelf-reported irritabilityPrevalence of irritabilityIrritable moodParent reportAssociations of irritabilityMental Health of ChildrenLevels of irritabilityAssessment of irritabilityAdolescent femalesMental health problemsPediatric irritabilityPsychopathological symptomsTemper outburstsHealth of ChildrenPsychiatric disordersPsychiatric riskDevelopmental trajectoriesEmotional problemsSelf-reportMoodMental healthAdolescent malesLongitudinally Designed StudyChildren aged 5BackgroundMost researchPlace-based approaches to improve the mental health and wellbeing of children and young people: a rapid realist review
March A, Allen K, Davies K, Harris J, Bethel A, Kennedy L, Malhotra T, Stemp R, Alexandrescu B, Hobbs T, Fonagy P, Pilling S, Berry V. Place-based approaches to improve the mental health and wellbeing of children and young people: a rapid realist review. Systematic Reviews 2025, 14: 115. PMID: 40390084, PMCID: PMC12090407, DOI: 10.1186/s13643-025-02838-8.Peer-Reviewed Original ResearchConceptsContext-mechanism-outcome configurationsImprove young people's mental health.Young people's mental healthPlace-based approachMental healthRealist reviewPeople's mental healthWellbeing of childrenYoung Person's Advisory GroupImprove mental healthMental health servicesYoung peopleYoung people's needsPublic health concernHealth servicesPreventive interventionsResultsFifteen articlesCommunity stakeholdersGrey literatureWellbeing outcomesConclusionsThis reviewIsolated interventionAdvisory GroupExpert panelIntermediate outcomesPrescription Pain Medication Misuse with and Without Heroin Use Among Adolescents: relationships with Routine Healthcare, Family Support, Academic Performance, Violence, and Other Risky Behaviors
Jalilian-Khave L, Stefanovics E, Zhai Z, Potenza M. Prescription Pain Medication Misuse with and Without Heroin Use Among Adolescents: relationships with Routine Healthcare, Family Support, Academic Performance, Violence, and Other Risky Behaviors. Substance Use & Misuse 2025, 60: 1400-1410. PMID: 40383936, PMCID: PMC12187537, DOI: 10.1080/10826084.2025.2499945.Peer-Reviewed Original ResearchConceptsPrescription pain medication misusePain medication misuseFamily supportHealthcare participantsRisky behaviorsHeroin useMedication misuseOpioid misuseYouth Risk Behavior Survey dataPrescription pain medicationBehavior Survey dataRoutine healthcareHealthcare utilizationPublic health crisisChi-square analysisHigher oddsSurvey dataOdds ratioPain medicationHigh school respondentsAdjusted modelsAcademic performanceNegative healthOddsHealth crisis
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