2001
Letter to the Editor: Backbone 1H, 15N, and 13C resonance assignments of ARPP-19
Huang H, Chen Y, Horiuchi A, Tsai L, Liu H, Chyan C, Hsieh M, Liu C, Lin F, Greengard P, Nairn A, Shiao M, Lin T. Letter to the Editor: Backbone 1H, 15N, and 13C resonance assignments of ARPP-19. Journal Of Biomolecular NMR 2001, 19: 383-384. PMID: 11370788, DOI: 10.1023/a:1011214512601.Peer-Reviewed Original ResearchAnimalsCarbon IsotopesCattleDNA, ComplementaryHydrogenMagnetic Resonance SpectroscopyNitrogen IsotopesPhosphoproteinsProtein Conformation
1999
The design, synthesis, and biological evaluation of analogues of the serine-threonine protein phosphatase 1 and 2A selective inhibitor microcystin LA: rational modifications imparting PP1 selectivity
Aggen J, Humphrey J, Gauss C, Huang H, Nairn A, Chamberlin A. The design, synthesis, and biological evaluation of analogues of the serine-threonine protein phosphatase 1 and 2A selective inhibitor microcystin LA: rational modifications imparting PP1 selectivity. Bioorganic & Medicinal Chemistry 1999, 7: 543-564. PMID: 10220039, DOI: 10.1016/s0968-0896(98)00254-5.Peer-Reviewed Original ResearchMeSH KeywordsEnzyme InhibitorsMagnetic Resonance SpectroscopyMass SpectrometryMicrocystinsPeptides, CyclicPhosphoprotein PhosphatasesProtein Phosphatase 1Spectrophotometry, InfraredSubstrate SpecificityConceptsPP1 selectivityProtein phosphatase 1Serine-threonine proteinMicrocystin-LAFirst-generation analogsSmall molecule inhibitorsPhosphatase 1Observed selectivityBiological evaluationMolecular modeling analysisMolecule inhibitorsRational modificationSelectivityStructural modificationsSynthesisAnaloguesInhibition assaysPP1MicrocystinsProteinLaModificationAssaysInhibitors
1997
Characterization of novel calmodulin-binding peptides with distinct inhibitory effects on calmodulin-dependent enzymes
NEVALAINEN L, AOYAMA T, IKURA M, CRIVICI A, Hong Y, CHUA N, NAIRN A. Characterization of novel calmodulin-binding peptides with distinct inhibitory effects on calmodulin-dependent enzymes. Biochemical Journal 1997, 321: 107-115. PMID: 9003408, PMCID: PMC1218043, DOI: 10.1042/bj3210107.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCalcium-Calmodulin-Dependent Protein Kinase Type 2Calcium-Calmodulin-Dependent Protein KinasesCalmodulinCalmodulin-Binding ProteinsCattleCyclic Nucleotide Phosphodiesterases, Type 1Magnetic Resonance SpectroscopyMaleNeurosporaPeptide MappingPhosphoric Diester HydrolasesSpectrometry, FluorescenceTestis