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Jeffrey Testani, MD, MTR

Associate Professor of Medicine; Director of Heart Failure Research, Cardiovascular Medicine; Co-Director Heart & Vascular Center Clinical Research, Heart & Vascular Center

Contact Information

Jeffrey Testani, MD, MTR

Patient Care Locations

Mailing Address

  • Cardiovascular Medicine

    PO Box 208017

    New Haven, CT 06520

    United States

Appointments

Biography

My clinical training is as an advanced heart failure physician with formal research training in patient oriented translational research. My research program is supported by NIH and investigator-initiated industry sources and uses techniques of both translational and clinical research to further the mechanistic understanding of cardiac-renal interactions, fluid and sodium homeostasis, and diuretic resistance. The primary approach of my current research program is prospective mechanistic human studies in heart failure and kidney disease patients, for which we have established extensive infrastructure. N My lab has extensive expertise in biomarker research has established and maintains an extensive bioassay resource with the capability to determine an extensive range of analytes in human biological samples with complexity ranging from simple serum chemistries to complex analytes such as ultra-trace lithium by inductively coupled plasma mass spectrometry, deuterium concentration by IRMS, high dimension multiplex protein assays, and large and small molecules by liquid chromatography mass spectrometry.

Education & Training

  • Fellowship
    Hospital of the University of Pennsylvania (2012)
  • MS
    University of Pennsylvania Medical School (2012)
  • Research Fellowship
    Hospital of the University of Pennsylvania (2011)
  • Fellowship
    Hospital of the University of Pennsylvania (2009)
  • Residency
    Hospital of the University of Pennsylvania (2007)
  • Internship
    Hospital of the University of Pennsylvania (2005)
  • MD
    University of Florida (2004)

Activities

  • Assessing and Optimizing Diuretic Response in Advanced Heart Failure: Is it Urine Sodium, Chloride or Output that Matters?
    Long Beach, CA, United States 2024
    NKF 2024 Spring Clinical Meetings
  • TBD
    Barcelona, CT, Spain 2024
    KDIGO Controversies Conference on Heart Failure and Chronic Kidney Disease
  • Cardiology Grand Rounds
    Hartford, CT, United States 2023
    Cardiology Grand Rounds
  • TBD
    Philadelphia, PA, United States 2023
    AHA Scientific Sessions 2023
  • Kidney Biomarkers to Guide Diuresis in Patients with Acute Decompensated Heart Failure
    Philadelphia, PA, United States 2023
    ASN Kidney Week 2023
  • “Pushers” to Enhance Renal Blood Flow in Acute Heart Failure
    Cleveland, OH, United States 2023
    HFSA Annual Scientific Meeting 2023
  • Urine sodium concentration in patients with AHF – How did we get here?
    Cleveland, OH, United States 2023
    HFSA Annual Scientific Meeting 2023
  • Implantable inferior vena cava sensors to monitor congestion
    Amsterdam, NH, Netherlands 2023
    ESC Congress 2023 Amsterdam
  • Heart Failure Grand Rounds
    New York, NY, United States 2023
    Heart Failure Grand Rounds
  • Cardiology Grand Rounds
    Dallas, TX, United States 2023
    Cardiology Grand Rounds
  • Cardiac-Renal interactions in Salt Balance
    Long Beach, CA, United States 2023
    American Physiological Society, Physiology Summit on New Physiology of Salt Balance
  • Diuretics and overcoming resistance
    Philadelphia, PA, United States 2023
    Penn Medicine Symposium on Heart Failure with Preserved Ejection Fraction (HFpEF)
  • Treading Water: Managing Heart Failure in the Presence of CKD
    Virtual 2022
    Kaiser Permanente Southern California Nephrology Mini-University
  • Zero sodium PD solutions
    online academic conference 2022
    The Renal Replacement Therapy Forum 2022
  • Permissive hypercreatininemia in diuresing patients with acute decompensated heart failure
    Chicago, IL, United States 2022
    American Heart Association Scientific Sessions
  • Cardiology Grand Rounds
    San Antonio, TX, United States 2022
    Cardiology Grand Rounds
  • HF and the Kidneys - Far reaching Implications
    Washington, DC, United States 2022
    HFSA Annual Scientific Meeting
  • Novel Devices for Decongestion
    Washington, DC, United States 2022
    HFSA Annual Scientific Meeting
  • Recent advances in devices and techniques to measure congestion: Volume-based diagnostics are superior
    Washington, DC, United States 2022
    HFSA Annual Scientific Meeting
  • Diuretic Management in Advanced Heart Failure
    Cleveland, OH, United States 2022
    University Hospitals Cleveland- Advanced Heart Failure Lecture
  • Cardio-Renal Interactions in Heart Failure
    Virtual 2022
    HFSA Virtual AHFTC Board Certification Review
  • Zero-sodium PD solutions: from porcine models to human trials
    Singapore, Singapore 2022
    International Society for Peritoneal Dialysis Congress
  • Cardiology Grand Rounds
    Newark, DE, United States 2022
    Cardiology Grand Rounds
  • State of the Art Presentation
    Austin, TX, United States 2022
    American College of Veterinary Internal Medicine Annual Specialist Forum
  • Renal Grand Rounds
    New York, NY, United States 2022
    Renal Grand Rands
  • Cardiology Grand Rounds
    Chicago, IL, United States 2022
    Cardiology Grand Rounds
  • Renal Grand Rounds
    Philadelphia, PA, United States 2022
    Renal Grand Rounds
  • The Kidney and Heart Failure
    San Diego, CA, United States 2022
    Scripps Clinical Advances in heart Failure and Shock Symposium
  • Risk Assessment, Management and Clinical Trajectory of Patients With Heart Failure
    Washington, DC, United States 2022
    American College of Cardiology 71st Annual Scientific Session
  • Inferior Vena Caval Size Monitoring
    New York, NY, United States 2022
    Technologies and Heart Failure Therapeutics (THT) 2022
  • Discussion of the Sequana Device
    New York, NY, United States 2022
    Technologies and Heart Failure Therapeutics (THT) 2022
  • Decongestion with the Reprieve Device
    New York, NY, United States 2022
    Technologies and Heart Failure Therapeutics (THT) 2022
  • Decongestion with the Reprieve Device
    New York, NY, United States 2022
    Technologies and Heart Failure Therapeutics (THT) 2022
  • Renal Grand Rounds
    Gainesville, FL, United States 2021
    Renal Grand Rounds
  • Empagliflozin in Heart Failure
    Boston, MA, United States 2021
    American Heart Association Scientific Sessions
  • VCU Cardiology Heart Failure Conference
    Richmond, VA, United States 2021
    VCU Cardiology Heart Failure Conference
  • Cardiology Grand Rounds
    Portland, ME, United States 2021
    Cardiology Grand Rounds
  • Diuretic Resistance
    Cleveland, OH, United States 2021
    Cleveland Clinic Heart Failure Research Symposium

Professional Service

OrganizationRoleDate
JACC: Heart FailureSection Editor of Kidney in Heart Failure2023 - Present
Circulation: Heart FailureEditorial Board Member2023 - Present
Journal of American Medical AssociationReviewer2023 - Present
Technical Expert Panel (TEP), Department of Veterans AffairsMember of a Technical Expert Panel (TEP) for an evidence synthesis on “Decompensated Heart Failure and Dietary Sodium.” This review is commissioned by the Department of Veterans Affairs (VA), Health Services Research & Development, and is being conducted by the Providence Evidence Synthesis Program (ESP) Center. 2023 - Present
NIH/NHLBI Loan Repayment ProgramReviewer2022 - Present
Journal of The American College of Cardiology Heart FailureSection Editor of the Kidney in Heart Failure Section2022 - Present
Journal of the Society for Cardiovascular Angiography and InterventionsEditorial Board2022 - Present
3ive Labs, 3ive LabsClinical trial steering committee2021 - Present
Lilly, LillyClinical trial steering committee and co-PI2021 - Present
NIH/NHLBI Mentored Patient Oriented ResearchReviewer2021
Reprieve cardiovascualr, Reprieve CardiovascularClinical trial steering committee2020 - Present
NIH/NHLBI Mentored Patient Oriented ResearchReviewer2020
NIH//PBKD Special Emphasis Panel Review of Small Business Applications in Kidney-Urologic DiseasesReviewer2020
NIH/NHLBI Catalyze ProgramReviewer2020
Heart Failure Society of AmericaReviewer/judge and chair of the 2020 Jay N. Cohn New Investigator Award – Basic Science / Clinical2020
Boehringer Ingelheim, Boehringer IngelheimEmpagliflozin Scientific Advisory Board2019 - Present
Cardionomic, CardionomicClinical trial steering committee2019 - Present

Departments & Organizations