William Asch, MD/PhD, BA

My clinical, educational, administrative, and scholarly efforts are centered on solid organ transplantation.  While the majority of this effort focuses on kidney transplantation, I provide subspecialty consultative services to the liver, heart, and bone marrow transplant programs.  As the Transplant Nephrology Fellowship Program Director, I established the required policies, procedures, and documents required to establish this program. The program is accredited through the American Society of Transplantation.  Yale is one of 62 accredited programs in the US.  Approved by the Yale Office of Graduate Medical Education, The Yale Transplant Nephrology Fellowship Program has graduated 6 fellows.  My scholarly activities range from an Investigator-Initiated Research project investigating the neurocognitive impairments associated with tacrolimus, the cornerstone immunosuppressant used to prevent rejection in solid organ transplant recipients.  The favorable proof of concept results (confirming that clinicians can perform a high level cognitive assessment in the clinic setting using the NIH-Tool Box Cognitive Battery) and pilot data have led to this project expanding into 16 site multicenter trial (The ABCs Trial).  In addition, I am the Principal Investigator for pharmaceutical sponsored clinical trials on immune tolerance, BK viremia, and delayed progression of diabetic kidney disease.