Silvia Vilarinho, MD, PhD

Assistant Professor of Medicine (Digestive Diseases) and of Pathology

Departments & Organizations

Internal Medicine: Digestive Diseases | Liver Center


Yale Combined Program in the Biological and Biomedical Sciences (BBS): Molecular Medicine, Pharmacology, and Physiology

Yale Medicine


Silvia Vilarinho is a physician-scientist who uses genetics, genomics and human samples to investigate the molecular basis of various liver diseases of unknown etiology. Using these approaches, we have identified a new mendelian form of non-cirrhotic portal hypertension, a novel bile acid disorder due to ACOX2 deficiency and a new cholestatic disorder due to mutations in KIF12. Our research goal is to discover new genes important in liver function both in health and disease and to use cell biology and animal models to determine the specific mechanism(s) linking mutant gene to disease, with potential diagnostic, therapeutic and prognostic applications.

Education & Training

PhD University of Porto, Portugal (2008)
MD University of Porto, Portugal (2004)
Fellowship Yale University
Residency Yale University
Internship University of Minnesota
Board Certification AB of Internal Medicine, Internal Medicine (2012)

Honors & Recognition

  • Junior Faculty Samuel Kushlan Award (2017)

  • AASLD Sheila Sherlock Clinical and Translational Research Award (2015)

  • Samuel Kushlan Award for Excellence in Research during Digestive Diseases Fellowship (2015)

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Contact Info

Silvia Vilarinho, MD, PhD
Office Location
The Anlyan Center
300 Cedar Street, Rm S 213

New Haven, CT 06519
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