C. Patrick Lusk, PhD

Associate Professor of Cell Biology

Departments & Organizations

Cell Biology

Discovery to Cure Internship

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Biochemistry, Quantitative Biology, Biophysics and Structural Biology (BQBS) | Molecular Cell Biology, Genetics and Development

Office of Cooperative Research


Dr. Lusk has a long standing interest in fundamental cellular mechanisms of compartmentalization with an emphasis on those that govern the biogenesis of the nuclear envelope and nuclear pore complexes (NPCs). He has been studying the nuclear envelope and nuclear transport since his graduate work at the University of Alberta in Canada and has been trained during his postdoctoral fellowship by Günter Blobel at The Rockefeller University. During this time, he (with collaborators/colleagues) has provided substantial insight into how nuclear transport is regulated and how the NPC is assembled. Moreover, he has helped to develop yeast as a model to study integral membrane proteins that reside at the inner nuclear membrane. While it is generally understood that these proteins are essential factors in gene regulation and genome organization, which is reflected by the discovery of the “nuclear envelopathies”, they remain challenging to study. Dr. Lusk is leveraging his expertise in yeast cell biology and genetics with super-resolution and proteomic approaches to illuminate function at the nuclear periphery.

Education & Training

PhD University of Alberta (2005)
BS University of Alberta (1998)
Postdoctoral Fellow The Rockefeller University

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Contact Info

C. Patrick Lusk, PhD
Lab Location
Boyer Center for Molecular Medicine
295 Congress Avenue, Ste BCMM 247

New Haven, CT 06510
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Office Location
Boyer Center for Molecular Medicine
295 Congress Avenue, Ste BCMM 254B

New Haven, CT 06510
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Mailing Address
Cell BiologyPO Box 208002
333 Cedar Street

New Haven, CT 06520-8002

Lusk Lab Website

Research Image 1

Superresolution image of nuclear pore complexes