Mary O'Connor, MD

Professor of Orthopaedics and Rehabilitation; Director, Center for Musculoskeletal Care

Departments & Organizations

Orthopaedics & Rehabilitation: Joint Reconstruction: Arthritis & Joint Reconstruction Program | Ortho Clinical Faculty

Center for Musculoskeletal Care

Yale Medicine


As the inaugural Director of the Center for Musculoskeletal Care at Yale School of Medicine and Yale-New Haven Health, Dr. O'Connor brings together the traditional disciplines of orthopaedics, rheumatology, spine and sports medicine with ancillary services such as nutrition, behavioral health and complementary medicine to create a Center focused on integration, innovation and invigoration of patients, providers and payers. Research is a critical activity and includes translational studies and those targeting biological therapies for musculoskeletal conditions.

After graduating from Yale University with a degree in biochemistry, Dr. O'Connor attended Drexel University College of Medicine and the completed her orthopaedic surgery residency and fellowship at Mayo Clinic, Rochester, MN. She joined the staff at Mayo Clinic in Florida (MCF) and held numerous leadership roles including Chair of the Department of Orthopedic Surgery (MCF), Medical Director for Philanthropy (MCF), member of the Executive Operations Team (MCF) and Medical Director of the Office of Integrity and Compliance for Mayo Clinic. She has also served as President of the International Society of Limb Salvage, the American Association of Hip and Knee Surgeons, the Musculoskeletal Tumor Society, the Association of Bone and Joint Surgeons and the Ruth Jackson Orthopaedic Society. She is the Chair of the American Academy of Orthopaedic Surgery Diversity Advisory Board and Chair of the Movement is Life Caucus, a multi-stakeholder group committed to decreasing musculoskeletal healthcare disparities.

Education & Training

MD Drexel University College of Medicine (1985)
BA Yale University (1979)
Fellowship, Orthopedic Oncology Mayo Clinic College of Medicine
Orthopedic Surgery Residency Mayo Clinic College of Medicine
Board Certification AB of Orthopaedic Surgery, Orthopaedic Surgery (1993)

Honors & Recognition

  • The Corrine Farrell AwardInternational Skeletal Society (2009)

  • Distinguished ClinicianMayo Clinic in Florida (2004)

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Contact Info

Mary O'Connor, MD
Patient Care Locations
Yale Physicians Building
800 Howard Avenue

New Haven, CT 06519
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Yale New Haven Hospital Saint Raphael Campus
1450 Chapel Street

New Haven, CT 06511
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Mailing Address
Orthopaedics & RehabilitationYale New Haven Hospital St. Raphael Campus
1450 Chapel Street

New Haven, CT 06515