Jude Clancy, MD

Associate Professor Term; Director, Lead Management Program

Research Interests

Clinical Trials as Topic; Investigative Techniques; Analytical, Diagnostic and Therapeutic Techniques and Equipment

Public Health Interests

Cardiovascular Diseases; Clinical Trials

Research Organizations

Internal Medicine: Cardiovascular Medicine

Office of Cooperative Research

Research Summary

I perform clinical trials at Yale related to the treatment and ablation of arrhythmias as well as new cardiac device implants. I also perform clinical and basic science research in the field of pacemaker and defibrillator lead management and extraction.

Extensive Research Description

I am actively involved in clinical and animal research in the field of lead extraction. This involves the research of venous biology which results in the adherence and fibrosis of pacemaker and defibrillator leads. We collect tissue from the devices we extract and are trying to elucidate the mechanisms of tissue fibrosis and binding of leads to cardiac structures. In addition we perform research in the field of pacemaker and ICD infections. This includes using electronic medical systems to identify infected patients, identifying high risk features of individuals with cardiac device infections, and developing algorithms for best practice management of these patients to optimize outcomes. I also perform animal research to look at lead and cardiac structure interaction in a porcine model. Specifically we are trying to develop an animal model with accelerated fibrosis of pacemaker and defibrillator leads. This would allow us to study the biology of lead fibrosis, train other physicians in the techniques of lead extraction and develop and evaluate extraction tools. I have developed a rescue balloon to be used in extraction cases if there is a tear of the SVC. This balloon's purpose is to stabilize the patient so surgical repair can be performed. I developed it in animals and further evaluated its safety and efficacy in a multicenter trial in which Yale was the primary center. It is now the only rescue tool in extraction and is being routinely used on an international level. 

Selected Publications

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Contact Info

Jude Clancy, MD
Patient Care Locations
Yale CardiologyYale New Haven Hospital
20 York Street

New Haven, CT 06510
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Yale Heart and Vascular Outpatient Services
84 North Main Street, Fl 2

Branford, CT 06405
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Yale Cardiac ElectrophysiologyYale Physicians Building
800 Howard Avenue, Ste 2nd Floor

New Haven, CT 06519
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Yale CardiologyOld Saybrook Medical Center
633 Middlesex Turnpike

Old Saybrook, CT 06475
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Office Location
Fitkin Memorial Pavilion
789 Howard Avenue, Ste 3rd Floor

New Haven, CT 06519
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Mailing Address
Cardiovascular MedicinePO Box 208017
333 Cedar Street

New Haven, CT 06520-8017

Curriculum Vitae

3D imaging of the rescue balloon deployed in a porcine SVC

The balloon is a compliant balloon specifically designed to tamponade an SVC tear should it occur during extraction. The balloon was specifically designed to accommodate variations in human SVC size and anatomy.