Phosphate, PTH, and FGF23 as mediators of the rachitic growth plate

Research Faculty and Summary

Marie Demay, MD

Dr. Demay’s CORT-supported study is focused on identifying the molecular basis for susceptibility of chondrocytes to phosphate-mediated apoptosis. This work characterizes hormone and growth factor (PTH, FGF23 and 1,25-dihydroxyvitamin D) effects on phosphate-mediated apoptosis using in vitro and in vivo models.

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