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Selected Publications

  1. Holm IA, Econs MJ, Carpenter TO. Familial hypophosphatemia and related disorders. In: Glorieux FH, Juppner H, Pettifor JM, editors. Pediatric Bone: Biology & Diseases. 2nd ed. San Diego: Elsevier; 2012. p. 699-726.
  2. Carpenter TO, Imel EA, Holm IA, Jan de Beur SM, Insogna KL. A clinician's guide to X-linked hypophosphatemia. J Bone Min Res 26:1381-1388, 2011. PMCID: PMC3157040
  3. Liang G, Vanhouten J, Macica CM. An atypical degenerative osteoarthropathy in Hyp mice is characterized by a loss in the mineralized zone of articular cartilage. Calcif Tissue Int 89:151-62, 2011. PMID: 21643724 [PMC Journal – In Process]
  4. Macica CM, Liang G, Nasiri A, Broadus AE. Genetic evidence of the regulatory role of parathyroid hormone-related protein in articular chondrocyte maintenance in an experimental mouse model. Arthritis Rheum 63:3333-43, 2011. PMCID: PMC3197958
  5. Sims-Lucas S, Cusack B, Eswarakumar VP, Zhang J, Wang F, Bates CM. Independent roles of Fgfr2 and Frs2alpha in ureteric epithelium. Development 138:1275-80, 2011. PMCID: PMC3050660
  6. Sims-Lucas S, Cusack B, Baust J, Eswarakumar VP, Masatoshi H, Takeuchi A, Bates CM. Fgfr1 and the IIIc isoform of Fgfr2 play critical roles in the metanephric mesenchyme mediating early inductive events in kidney development. Dev Dyn 240:240-9, 2011. PMCID: PMC3093196
  7. Liu ES, Carpenter TO, Gundberg CM, Simpson CA, Insogna KL. Calcitonin administration in X-linked Hypophosphatemia. N Engl J Med 364:1678-80, 2011. PMCID: PMC3162370
  8. Brownstein C, Zhang J, Stillman A, Ellis B, Troiano N, Adams DJ, Gundberg CM, Lifton RP, Carpenter TO. Increased bone volume and correction of HYP mouse hypophosphatemia in the Klotho/HYP mouse. Endocrinology 151:492-501, 2010. PMCID: PMC2817612
  9. Xiao L, Naganawa T, Lorenzo J, Carpenter TO, Coffin JD, Hurley MM. Nuclear isoforms of fibroblast growth factor 2 are novel inducers of hypophosphatemia via modulation of FGF23 and Klotho. J Biol Chem 285:2843-46, 2010. PMCID: PMC2807337
  10. Imel EA, DiMeglio LA, Hui SL, Carpenter TO, Econs MJ. Treatment of XLH with calcitriol and phosphate increases circulating FGF23 concentrations. J Clin Endocrinol Metab 95:1846-50, 2010. PMCID: PMC2853995
  11. Miedlich SU, Zalutskaya A, Zhu ED, Demay MB. Phosphate-induced apoptosis of hypertrophic chondrocytes is associated with a decrease in mitochondrial membrane potential and is dependent upon Erk1/2 phosphorylation. J Biol Chem 285:18270-5, 2010. PMCID: PMC2881751
  12. Miedlich SU, Zhu ED, Sabbagh Y, Demay MB. The receptor-dependent actions of 1,25-dihydroxyvitamin D are required for normal Growth Plate Maturation in Npt2a knockout mice. Endocrinology 151:4607-12, 2010. PMCID: PMC2946147
  13. Wigner NA, Luderer HF, Cox MK, Sooy K, Gerstenfeld LC, Demay MB. Acute phosphate restriction leads to impaired fracture healing and resistance to BMP-2. J Bone Miner Res 25:724-33, 2010. PMCID: PMC3153327
  14. Carpenter TO, Insogna KL, Zhang JH, Ellis B, Nieman S, Simpson C, Olear E, Gundberg CM. Circulating levels of soluble Klotho and FGF23 in X-linked hypophosphatemia: circadian variance, effects of treatment, and relationship to parathyroid status. J Clin Endocrinol Metab 95:E352-7, 2010. PMCID: PMC 2968736
  15. 2010 YC-XLH Newsletter