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Clinical Programs

Pediatric Neurology's strong clinical and research interests are dyslexia, diseases of muscle and nerve, headaches, neonatal neurology, movement and paroxysmal disorders, multiple sclerosis, spina bifida, stroke and cerebrovascular disorders, seizures and epilepsy, and disorders learning and attention.

The Yale Center for Dyslexia and Creativity

The mission of The Yale Center for Dyslexia & Creativity is to uncover and illuminate the strengths of individuals with dyslexia, disseminate the latest innovations from scientific research, translate them into practice, and transform the care of children and adults with dyslexia. Founded and co-directed by Sally E. Shaywitz, M.D., the Audrey G. Ratner Professor in Learning Development and Bennett A. Shaywitz, M.D., the Charles and Helen Schwab Professor in Dyslexia and Learning Development, both elected members of the National Academy Medicine of the National Academy of Sciences, the Center is a leading source for trustworthy information about dyslexia and advocacy in ensuring that scientific knowledge is translated into policy and practice. As part of its innovative approach to changing attitudes, the Center targets specific strategies that improve the lives of dyslexic children and adults. Strategies include: neurobiological and longitudinal research, focused conferences, courses and seminars, media (print and film), and evidence and methods to support the translation of research into practice. In addition, The Center strives to create a level playing field for those with dyslexia, and does so, in part, by educating policymakers and empowering individuals to take a stance in their communities, schools, and workplaces.

Learn more at the Yale Center for Dyslexia and Creativity website.

The Pediatric Epilepsy Center

The Pediatric Epilepsy Center studies and treats epilepsy and seizure disorders. The Center is equipped with state-of-the-art technology for continuous electroencephalographic and video monitoring of seizures in infants and children. This facility represents one component of a comprehensive evaluation and treatment program for children with epilepsy. Recognizing that six percent of the pediatric population experiences at least one seizure in a lifetime, Pediatric Neurology is committed to understanding the nature of seizure disorders in children.

Our team of dedicated experts offers a multidisciplinary approach to care that integrates the expertise of colleagues in neurosurgery and diagnostic imaging to deliver leading-edge evaluation, diagnosis, and patient care to children with varying forms and degrees of seizure and epilepsy. Our Program provides intensive audiovisual and electroencephalography (EEG) monitoring for diagnosis and localization of the affected area, to tailor care for each patient. Patients receive comprehensive inpatient and outpatient services, and a full range of medical and surgical treatment options, including ketogenic diet and vagus nerve stimulator programs for the treatment of children with complex epileptic conditions, as well as investigative therapies and approaches that are not widely available.

Ketogenic Diet Clinic

Our philosophy is patient focused and we strive to incorporate the family’s cultural background and dietary preferences. Parents and caregivers receive comprehensive training in recipe preparation, cooking, along with how to identify and treat any side effects of the diet. In addition to providing ongoing comprehensive care, our team is actively involved in research dedicated to improving outcomes and management of side effects.

This is a medical nutrition therapy – a diet that should only be conducted under the supervision of a multi-disciplinary medical team including a Registered Dietitian Nutritionist.

Please visit the Yale New Haven Health site for two videos on this topic.

The Neonatal Brain Research Group

The organization of structural and functional brain networks is necessary for typical neurodevelopment, and recent data suggest that many neurobehavioral disorders are attributable to developmental disorders of fetal brain growth and connectivity. Emergence of the developing connectome is contingent on adequate nutrition and good prenatal care, but mostly on unknown genetic and metabolic cues and factors. To date, identification of these crucial cues and factors has been impeded by the inability to non-invasively and serially interrogate the developing human fetus and to correlate natural undulations in expressed genes with brain growth and maturation. The simultaneous and recent explosive growth in two disciplines – high resolution imaging and next-generation sequencing – now make the entirety of a developing human fetus accessible at serial key developmental milestones during gestation, all non-invasively and safe to mother and fetus.

The focus of the Neonatal Brain Research Group, led by Laura R Ment, MD, is the identification of sensitive, reliable and actionable biomarkers of growth and maturation of the developing fetal brain using sophisticated fetal magnetic resonance imaging strategies and emerging molecular technologies.

The Pediatric Movement Disorders Clinic

The Pediatric Movement Disorders Clinic was established to evaluate and treat children with dystonia, chorea, myoclonus, tremor, motor tics, stereotypies and other paroxysmal disorders of movement. Dr. Nigel Bamford works closely with the Child Study Center at Yale, the Yale Comprehensive Movement Disorders Program, and the Department of Neurosurgery to enhance clinical evaluation and available treatments. The clinic is located at Yale New Haven Hospital.

The Spina Bifida Clinic

Spina bifida occurs early in embryo development often before a woman even knows she is pregnant. Spina bifida is commonly diagnosed prenatally by ultrasound screening, and the spina bifida clinic team works closely with the Yale Maternal-Fetal Medicine clinic in prenatal consultation. Infants with spina bifida are usually delivered by cesarean section at a medical center such as Yale-New Haven Children’s Hospital equipped with a neonatal intensive care unit and staffed by a specialized neurosurgical team to repair the opening shortly after birth. Dr. Cristian Ionita in pediatric neurology works with a team of neurosurgeons, orthopedists, urologists, physical therapists, nurses, dietitians and social workers to provide long-term support to children with spina bifida and their families. Children with neural tube defects have varying degrees of central nervous system problems as well as difficulties with bladder and bowel control and lower limb movement. A coordinated care plan is developed by our multidisciplinary spina bifida clinic team.

The Comprehensive Pediatric Headache Clinic

The Pediatric Headache Clinic provides comprehensive diagnostic and management services for children and adolescents with headaches. Our clinic is comprised of a neurologist, nurse practitioner, nurse coordinator, pediatric psychologists, and clinical social worker. We believe that a strong collaboration amongst our team members, the patient and family, school personnel, and primary care provider is essential to providing the best care for your child. Headaches and chronic pain are complex; therefore, our clinical team uses a biopsychosocial approach to understand how headaches relate to a child’s environment, emotional and behavioral well-being, and school and family functioning. Our recommendations are intended to support your child’s overall functioning with the goal of attending school and engaging in other life-fulfilling activities.

Children and families meet with one or more members of the team during the appointment.The team will conduct an initial assessment to learn more about your child’s headaches. Maintaining a headache diary prior to the visit can help to identify patterns and triggers for your child’s headaches.

Our multidisciplinary team will then work together to formulate an individualized treatment plan for your child. Treatment often involves basic lifestyle modifications to diet, hydration, exercise, and sleep. Certain pediatric headaches may require additional testing, although most do not. Medication may be recommended as well. We look forward to meeting with you and your child in headache clinic.

The Yale Multiple Sclerosis Center

The Yale Multiple Sclerosis Center is a multidisciplinary service that evaluates and treats patients with suspected or diagnosed multiple sclerosis (MS). MS is a chronic central nervous system disease that causes symptoms ranging from numbness to weakness. Up to 10 percent of MS patients are diagnosed before the age of 18. The disease has different effects in these younger patients whose brains are still developing.

Pediatric neurologist, Naila Makhani, MD MPH evaluates and treats these younger patients. She has significant experience in MS, receives funding from Race to Erase MS and participates in clinical trials for MS therapies in children.

Dr. Makhani sees children under 12 years of age at the Long Wharf Medical Center (1 Long Wharf Drive, New Haven) and children 13 and older at the Yale Multiple Sclerosis Center on 6 Devine St in North Haven, CT, just a 10 minute drive from the main Yale Medical Center campus.

The Yale Multiple Sclerosis Center offers streamlined resources including sophisticated brain imaging, pharmacy, an infusion center, and phlebotomy. A specialized nurse is available to answer questions about disease modifying therapies. Social work and nutrition consultants are available. In addition, there are opportunities to participate in MS clinical trials, research studies, and regularly scheduled clinical care conferences.

The Pediatric Muscular Dystrophy Program

The Yale Pediatric Neuromuscular/MDA Clinic is one of only five pediatric clinics in New England that is supported, in part, by the Muscular Dystrophy Association (MDA). Families of children with muscular dystrophy or other childhood neuromuscular disorders can see a multidisciplinary team which includes a neurologist, cardiologist, pulmonologist, orthopedic surgeon, physical and occupational therapist, social worker, dietician, and care coordinator, as well as easy access to other specialties such as genetics. Basic diagnostic imaging, pulmonary function tests, and echocardiography occur on site. Members of the team may be seen together or separately, in one visit.

The Co-Directors of the clinic are Dr. Cristian Ionita, Clinical Associate Professor of Pediatrics and Neurology, and Dr. Brian G Smith, Professor of Orthopedics.

Along with other members of the team, they provide comprehensive evaluation and clinical care. The clinic is located in Yale-New Haven Children’s Hospital’s Pediatric Specialty Center at One Long Wharf, One Long Wharf is a short drive from Yale New Haven Hospital and has free parking with ample spaces and easy access for individuals with impairments.