De Aquino Awarded IMPOWR-YOU Grant to Study Pain Sensitivity, Opioid Use Disorder
Joao P. De Aquino, MD, assistant professor of psychiatry, has been awarded a pilot grant from the Integrative Management of Chronic Pain and Opioid Use Disorder for Whole Recovery-Yale and Organizations United (IMPOWR-YOU) Research Center to evaluate the relationship between pain sensitivity and brain synaptic density among people with opioid use disorder (OUD).
$15M NIDA Grant Awarded to Serena Spudich, Mark Gerstein, and Yuval Kluger
Principal Investigators Serena Spudich, MD, MA (Neurology), Mark Gerstein, PhD (Molecular Biophysics and Biochemistry), and Yuval Kluger, PhD (Pathology) were recently awarded a $15 million grant from the National Institute on Drug Abuse (NIDA) to establish a Data Center to coordinate, analyze, and make accessible single-cell and other molecular data sets generated by Single-Cell Opioid Responses in the Context of HIV (SCORCH) and other NIDA-funded HIV and substance use disorder projects.
Teen vaping is bad. Nicotine makes it worse, says researcher
Companies that make vaping liquids must now comply with a U.S. Food and Drug Administration policy released last month banning vape liquids that taste like anything but tobacco or menthol. But vaping still delivers something highly appealing and addictive: nicotine. And researchers are just beginning to study the drug’s long-term impact on the developing brain.Source: Science Mag
Child deaths from opioids nearly tripled in recent years, says Yale study
Close to 9,000 children and teens in the United States died from opioid poisonings over the last two decades, representing a nearly three-fold increase in mortality rates, Yale researchers said. These findings illustrate how the opioid epidemic continues to evolve and harm children even as efforts to confront the crisis through treatment and limits on opioid prescribing ramp up, they said.
Rx opioid poisonings nearly double among toddlers, teens
Thousands of children are hospitalized annually for prescription opioid poisonings, and in recent years, hospitalization rates have nearly doubled among children of all ages, according to a new Yale study that shows toddlers and older teens are particularly at risk.
Impact of Cannabis Use, Substance Use Disorders, and Psychiatric Diagnoses on COVID-19 Outcomes: A Retrospective Cohort Study
COVID-19 patients with substance use disorders had greater likelihood of requiring critical interventions, such as ICU admission and ventilatory support. Substance use disorders and psychiatric diagnoses were also associated with a longer duration of hospitalization and greater number of hospital admissions.Source: The Journal of Clinical Psychiatry
A call to prioritize substance use treatment in children
While nearly 6 million adolescents and young adults in the United States have a substance use disorder, only 8% receive treatment, according to data collected in 2019. This treatment gap is a critical problem, says Deepa Camenga, associate professor of emergency medicine at Yale School of Medicine and associate director of pediatric programs for the Yale Program in Addiction Medicine.Source: Yale News
Yale Scientists Identify Genetic Risk Factors for Opioid Use and Related Substance Use Disorders
A new human genomics study led by Yale scientists has identified genetic risk factors for opioid use disorder (OUD) and related substance use disorders according to a new large-scale genome-wide association study – increasing the number of risk genes known from 1 to 19.
Le Zhang, PhD Wins Avenir Award for Research on Substance Use Disorders and HIV/AIDS
Assistant Professor Le Zhang, PhD was recently awarded a DP2 grant from the National Institutes of Health (NIH), entitled “Immune Network Dysregulation of the Central Nervous System with HIV Persistence and Opioid Abuse.” The grant, which amounts to more than $2.5 million, began on May 15, 2022 and lasts for four years.
Patients with Opioid Use Disorder Treated in Emergency Departments Shed Light on Their Unmet Needs and Opportunities to Improve Care in Yale-Led Study Published in JAMA Network Open
To better understand the experiences of patients with OUD on receiving care in the ED and to identify opportunities to improve care, Yale researchers led a collaboration with New York University, John’s Hopkins University, University of Cincinnati, Mount Sinai Hospital in New York, and the University of Washington. Between June 2018 and January 2019. They conducted focus groups with ED patients across six academic, community, and public safety net EDs in Baltimore, MD, Cincinnati, OH, New York City, NY, Seattle, WA and Claremont, NH, as part of two NIDA Clinical Trials Network studies.
Stressed Out and Locked-Down During Pandemic, New Yorkers Craved Alcohol, YSPH Study Finds
As New York state’s lockdown orders wore on in the early months of the COVID-19 pandemic, residents increasingly felt cravings for alcohol — and reported subsequently misusing it, a new study from scientists at the Yale School of Public Health and Stony Brook University has found.