1999
Cloning of a Novel MHC-Encoded Serine Peptidase Highly Expressed by Cortical Epithelial Cells of the Thymus
Bowlus C, Ahn J, Chu T, Gruen J. Cloning of a Novel MHC-Encoded Serine Peptidase Highly Expressed by Cortical Epithelial Cells of the Thymus. Cellular Immunology 1999, 196: 80-86. PMID: 10527559, DOI: 10.1006/cimm.1999.1543.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsAntigen PresentationAntigens, Differentiation, B-LymphocyteBase SequenceCarboxypeptidasesConsensus SequenceCosmidsEpithelial CellsFluorescent Antibody Technique, IndirectGenesHistocompatibility Antigens Class IIHumansIn Situ HybridizationLysosomesMajor Histocompatibility ComplexMiceMice, Inbred C57BLMolecular Sequence DataSequence AlignmentSequence Homology, Amino AcidSerine EndopeptidasesThymus GlandConceptsCortical thymic epithelial cellsAntigen-presenting cellsThymic epithelial cellsEpithelial cellsMHC class II presentationClass II antigen processingMHC class II antigen processingClass II presentationCortical epithelial cellsMajor histocompatibility complex regionThymic capsuleThymic cortexAntigen presentationT cellsSerine proteasesStrong stainingNovel MHCAntigen processingInvariant chainCathepsin SProteolytic milieuThymusPresentationSitu hybridizationStaining
1995
Cloning of a New "Finger" Protein Gene (ZNF173) within the Class I Region of the Human MHC
Chu T, Capossela A, Coleman R, Goei V, Nallur G, Gruen J. Cloning of a New "Finger" Protein Gene (ZNF173) within the Class I Region of the Human MHC. Genomics 1995, 29: 229-239. PMID: 8530076, DOI: 10.1006/geno.1995.1236.Peer-Reviewed Original ResearchMeSH KeywordsAlpha-FetoproteinsAmino Acid SequenceAnimalsBase SequenceCloning, MolecularConsensus SequenceConserved SequenceDNA-Binding ProteinsDNA, ComplementaryGene LibraryGenes, MHC Class IHominidaeHumansKidneyMajor Histocompatibility ComplexMiceMolecular Sequence DataRestriction MappingSequence Homology, Amino AcidZinc FingersConceptsFull-length cDNA cloneClass I regionHuman coding regionsPartial genomic cloneHuman MHCConceptual proteinFinger proteinGenomic clonesPositional cloningCDNA clonesCDNA sequenceProtein genePolyglutamic acid regionCarboxyl terminusI regionBiological roleCoding regionsAcid regionRelated sequencesGenesMultiple tissuesProteinMajor histocompatability complexCloningNucleic acids