1986
Glucocorticoid stimulation of choline-phosphate cytidylyltransferase activity in fetal rat lung: Receptor-response relationships
Rooney S, Dynia D, Smart D, Chu A, Ingleson L, Wilson C, Gross I. Glucocorticoid stimulation of choline-phosphate cytidylyltransferase activity in fetal rat lung: Receptor-response relationships. Biochimica Et Biophysica Acta 1986, 888: 208-216. PMID: 3017448, DOI: 10.1016/0167-4889(86)90023-6.Peer-Reviewed Original ResearchConceptsEffect of dexamethasoneDexamethasone bindingCholine-phosphate cytidylyltransferase activitySpecific dexamethasone bindingFetal lung maturationFetal rat lung explantsCholine-phosphate cytidylyltransferaseSpecific nuclear bindingCytidylyltransferase activityRat lung explantsReceptor-mediated processSupernatant fractionFetal rat lungDose-response curveDexamethasone-treated culturesLung maturationGlucocorticoid bindingGlucocorticoid actionDe novo phosphatidylcholine synthesisLung explantsRat lungDexamethasoneGlucocorticoid stimulationStimulatory effectCholine incorporation
1974
Fatty Acid Synthesis in Developing Brain
Gross I, Warshaw J. Fatty Acid Synthesis in Developing Brain. Neonatology 1974, 25: 365-375. PMID: 4156483, DOI: 10.1159/000240709.Peer-Reviewed Original ResearchConceptsFatty acid synthesisMaximal brain growthFatty acid synthetase activityRat brainBrain supernatant fractionPostnatal lifeSupernatant fractionBrain growthAcid synthesisAdult levelsFatty acid synthetaseAcetyl-CoA carboxylase activityBrainAcetyl-CoA carboxylaseSynthetase activityFourfold differenceActivityWeeks