2025
Risk of Bacterial Infections in Febrile Infants 61 to 90 Days Old With Respiratory Viruses.
Aronson P, Mahajan P, Nielsen B, Olsen C, Meeks H, Grundmeier R, Kuppermann N. Risk of Bacterial Infections in Febrile Infants 61 to 90 Days Old With Respiratory Viruses. 2025, 156 PMID: 40506050, DOI: 10.1542/peds.2025-070617.Peer-Reviewed Original ResearchConceptsPrevalence of urinary tract infectionUrinary tract infectionPediatric Emergency Care Applied Research NetworkRespiratory viral testingRespiratory viral infectionsFebrile infantsBacterial meningitisRespiratory virusesSARS-CoV-2Viral testingViral infectionSARS-CoV-2-positive infantsBacterial infectionsRisk of bacterial infectionPrevalence of bacteremiaPrevalence of bacterial infectionRespiratory syncytial virusBlood culturesTract infectionsPositive infantsSyncytial virusNegative infantsBacteremiaMeningitisInfantsUrine Dipstick for the Diagnosis of Urinary Tract Infection in Febrile Infants Aged 2 to 6 Months.
Hunt K, Green R, Sartori L, Aronson P, Chamberlain J, Florin T, Michelson K, Monuteaux M, Chaudhari P, Nigrovic L. Urine Dipstick for the Diagnosis of Urinary Tract Infection in Febrile Infants Aged 2 to 6 Months. 2025, 155 PMID: 40122108, DOI: 10.1542/peds.2024-068671.Peer-Reviewed Original ResearchMeSH KeywordsCarboxylic Ester HydrolasesCross-Sectional StudiesFemaleFeverHumansInfantLeukocyte CountMaleReagent StripsSensitivity and SpecificityUrinalysisUrinary Tract InfectionsConceptsDiagnosis of urinary tract infectionUrinary tract infectionUrine WBC countUrine dipstickUrine cultureAged 2 to 6Receiver operating characteristicWhite blood cellsTract infectionsColony-forming unitsUrine white blood cellsWBC countCatheterized urine culturePositive urine dipstickInitial treatment decisionsAccurate diagnostic testCross-sectional studyBacterial uropathogensFebrile infantsLaboratory urinalysisTreatment decisionsDiagnostic testsEmergency departmentUrinalysisUrine
2023
Prevalence of Urinary Tract Infection, Bacteremia, and Meningitis Among Febrile Infants Aged 8 to 60 Days With SARS-CoV-2
Aronson P, Louie J, Kerns E, Jennings B, Magee S, Wang M, Gupta N, Kovaleski C, McDaniel L, McDaniel C, Agbim C, Amadasun O, Beam N, Beamon B, Becker H, Bedard E, Biondi E, Boulet J, Bray-Aschenbrenner A, Brooks R, Chen C, Corboy J, Dawlabani N, De Angulo G, Demie S, Drexler J, Dudley N, Ellis A, Fath K, Frauenfelder A, Gill J, Graf T, Grageda M, Greening H, Griffin A, Groen A, Guernsey III D, Gustafson S, Hancock W, Iyer S, Jaiyeola P, Jayanth A, Jennings R, Kachan-Liu S, Kamat A, Kennedy I, Khateeb L, Khilji O, Kleweno E, Kumar A, Kwon S, La A, Laeven-Sessions P, Le K, Leazer R, Levasseur K, Lewis E, Maalouli W, Mackenzie B, Mahoney K, Margulis D, Maskin L, McCarty E, Monroy A, Morrison J, Myszewski J, Nadeau N, Nagappan S, Newcomer K, Nordstrom M, Nguyen D, O'Day P, Oumarbaeva-Malone Y, Parlin U, Peters S, Piroutek M, Quarrie R, Rice K, Romano T, Rooholamini S, Schroeder C, Segar E, Seitzinger P, Sharma S, Simpson B, Singh P, Sobeih Y, Sojar S, Srinivasan K, Sterrett E, Swift-Taylor M, Szkola S, Thull-Freedman J, Topoz I, Vayngortin T, Veit C, Ventura-Polanco Y, Wallace Wu A, Weiss L, Wong E, Zafar S. Prevalence of Urinary Tract Infection, Bacteremia, and Meningitis Among Febrile Infants Aged 8 to 60 Days With SARS-CoV-2. JAMA Network Open 2023, 6: e2313354. PMID: 37171815, PMCID: PMC10182434, DOI: 10.1001/jamanetworkopen.2023.13354.Peer-Reviewed Original ResearchMeSH KeywordsBacteremiaCOVID-19COVID-19 TestingCross-Sectional StudiesFemaleHumansInfantMaleMeningitis, BacterialPrevalenceSARS-CoV-2Urinary Tract InfectionsConceptsPrevalence of UTIUrinary tract infectionSARS-CoV-2SARS-CoV-2-positive infantsSARS-CoV-2 testingFebrile infantsBacterial meningitisTract infectionsSARS-CoV-2 positivityMulticenter cross-sectional studyInflammatory marker levelsMedical record reviewProportion of infantsCross-sectional studyQuality improvement initiativesRecord reviewEmergency departmentMarker levelsLower proportionBacteremiaMAIN OUTCOMEMeningitisInfantsAge groupsBacterial infections
2022
Trends in Prevalence of Bacterial Infections in Febrile Infants During the COVID-19 Pandemic.
Aronson P, Kerns E, Jennings B, Magee S, Wang M, McDaniel C. Trends in Prevalence of Bacterial Infections in Febrile Infants During the COVID-19 Pandemic. 2022, 150 PMID: 36353853, DOI: 10.1542/peds.2022-059235.Peer-Reviewed Original ResearchMeSH KeywordsBacteremiaBacterial InfectionsCOVID-19Cross-Sectional StudiesFeverHumansInfantMeningitis, BacterialPandemicsPrevalenceRetrospective StudiesUrinary Tract InfectionsConceptsUrinary tract infectionInvasive bacterial infectionsCOVID-19 prevalenceFebrile infantsOdds of UTIPrevalence of UTIBacterial infectionsMulticenter cross-sectional studyEmergency department visitsMonths of presentationCoronavirus disease 2019 (COVID-19) pandemicCross-sectional studyDisease 2019 pandemicUTI prevalenceTract infectionsBacterial meningitisDepartment visitsLower oddsPrepandemic levelsInfantsInfants 8MeningitisBacteremiaLogistic regressionPrevalence
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