2025
Integrating exposomics into biomedicine
Miller G, Bennett L, Balshaw D, Barouki R, Bhutani G, Dolinoy D, Gao P, Jett D, Karagas M, Klánová J, Lein P, Li S, Metz T, Patel C, Pollitt K, Rajasekar A, Sillé F, Thessen A, Thuault-Restituito S, Vermeulen R, Ward-Caviness C, Wright R. Integrating exposomics into biomedicine. Science 2025, 388: 356-358. PMID: 40273259, DOI: 10.1126/science.adr0544.Peer-Reviewed Original ResearchEvaluating factors impacting early career physician-scientists’ decisions to continue research careers in the United States of America
Farhat K, Obradovic A, Siebert A, Tun H, Noch E, Kwan J. Evaluating factors impacting early career physician-scientists’ decisions to continue research careers in the United States of America. BMC Medical Education 2025, 25: 564. PMID: 40247298, PMCID: PMC12007356, DOI: 10.1186/s12909-025-07144-4.Peer-Reviewed Original ResearchMeSH KeywordsAdultBiomedical ResearchCareer ChoiceFemaleHumansMalePhysiciansResearch PersonnelSurveys and QuestionnairesUnited StatesConceptsPhysician-scientistsTraining programGraduates of training programsEarly-career physician-scientistsFisher's exact testWork-life balanceStages of clinical trainingMaintain work-life balancePhysician-scientist workforcePatient careExact testMethodsA surveyClinical trainingIncomplete responseUnited StatesLack of fundingNational surveyChi-squareCompare differencesSeeking employmentScientific innovationScientific trackResearch careerVulnerable communitiesResearch fundingUse of a pathogen X tabletop exercise to assess the operational response preparedness of an emerging infectious diseases research network
Lee R, Hemingway-Foday J, Batsuli N, Wagner L, Macoubray A, Garry R, Johnson C, Hanley K, Vasilakis N, Mboup S, Li H, Sánchez C, Rabinowitz P, Breiman R, Vandergrift N, Earley E, Bouton-Verville H, Beaubien E, Davidson E, Van Vliet G, Woodson S, Moody M, Sempowski G, Reithinger R. Use of a pathogen X tabletop exercise to assess the operational response preparedness of an emerging infectious diseases research network. Frontiers In Public Health 2025, 13: 1551996. PMID: 40213436, PMCID: PMC11983644, DOI: 10.3389/fpubh.2025.1551996.Peer-Reviewed Original ResearchMeSH KeywordsBiomedical ResearchCommunicable Diseases, EmergingCOVID-19Disease OutbreaksHumansPandemicsSARS-CoV-2Identifying and Responding to Gaps in the Academic Research Pipeline: Findings From the International Society for Autism Research (INSAR) Early Career Committee
Villalobos M, Vivanti G, Jayanath S, Carpenter K, Shen M, Shic F, Locke J. Identifying and Responding to Gaps in the Academic Research Pipeline: Findings From the International Society for Autism Research (INSAR) Early Career Committee. Autism Research 2025, 18: 717-724. PMID: 40125848, PMCID: PMC12015790, DOI: 10.1002/aur.70028.Peer-Reviewed Original ResearchMeSH KeywordsAutistic DisorderBiomedical ResearchCareer ChoiceHumansMentoringMentorsResearch PersonnelSurveys and QuestionnairesConceptsEarly career researchersInternational Society for Autism ResearchCareer researchersEarly career academicsAutism researchNetwork programmingCareer academicsField of autismProfessional collaborationMentoring initiativesAutism fieldInitial pilotResearch fieldSenior researchersMentoringNetworking opportunitiesResearch careerAcademicsJournal editorsPriorities for Research on Hypertension Care Delivery: A WHO Report Executive Summary
Matsushita K, Angell S, Appel L, Bygrave H, Cohn J, Kalyesubula R, Kaur P, Moran A, Mswema M, Schoj V, Schutte A, Shao R, Zhang X, Ordunez P, Khan T. Priorities for Research on Hypertension Care Delivery: A WHO Report Executive Summary. Hypertension 2025, 82: 971-976. PMID: 40109247, DOI: 10.1161/hypertensionaha.125.24702.Peer-Reviewed Original ResearchMeSH KeywordsAntihypertensive AgentsBiomedical ResearchDelivery of Health CareHumansHypertensionWorld Health OrganizationConceptsHypertension care deliveryHealth system reformCare deliveryWorld Health OrganizationHypertension careTrained community health workersResearch prioritiesTrained health care workersHealth OrganizationTask-sharing approachesCommunity health workersHealth care workforceImprove medication adherenceHypertension control programHealth care workersSystem reformLow/middle-income countriesLeadership teamCare workforceHealth workersImplementation researchMedication adherenceManagement of hypertensionThematic frameworkCare workersResearch Priorities in Neuropalliative Care
Lau W, Fehnel C, Macchi Z, Mehta A, Auffret M, Bogetz J, Fleisher J, Graber J, Leeper H, Manglani-Terranova H, Muehlschlegel S, Mroz E, Pedowitz E, Ramanathan U, Sarmet M, Shlobin N, Sokol L, Weeks S, Xu J, Medsger H, Creutzfeldt C, Vranceanu A, Zahuranec D, Hwang D. Research Priorities in Neuropalliative Care. JAMA Neurology 2025, 82: 295-302. PMID: 39899319, DOI: 10.1001/jamaneurol.2024.4932.Peer-Reviewed Original ResearchMeSH KeywordsBiomedical ResearchConsensusHumansNervous System DiseasesNeurologyPalliative CareResearchSocieties, MedicalConceptsNeuropalliative careCare partnersIntegration of palliative careSpecialty palliative care servicesGoal-concordant carePalliative care servicesInterdisciplinary panel of expertsArea of practiceImprove quality of lifeQuality of lifePalliative careCare interventionsCare servicesPanel of expertsDelivery modelsPriority research areasCareInterdisciplinary panelImprove qualityCare SocietyResearch prioritiesResearch funding mechanismsResearch CommitteeSpecialized communicationNeurological diseasesAn international perspective on the future of systemic sclerosis research
Abraham D, Black C, Denton C, Distler J, Domsic R, Feghali-Bostwick C, Gourh P, Hinchcliff M, Kolling F, Kuwana M, Lafyatis R, Landegren U, Mahoney J, Martin J, Matucci-Cerinic M, McMahan Z, Mora A, Mouthon L, Rabinovitch M, Rojas M, Rubin K, Trojanowska M, Varga J, Whitfield M, Gabrielli A, Krieg T. An international perspective on the future of systemic sclerosis research. Nature Reviews Rheumatology 2025, 21: 174-187. PMID: 39953141, DOI: 10.1038/s41584-024-01217-2.Peer-Reviewed Original ResearchConceptsSystemic sclerosisSystemic sclerosis researchHistory of systemic sclerosisInnovative clinical trial designsSystemic autoimmune diseaseEarly pathogenetic eventClinical trial designCollaborative global effortAutoimmune phenomenaImprove patient outcomesDisease activityMicrovascular dysfunctionClinical historyEmergency therapyAutoimmune diseasesDisease-modifying treatmentsTissue fibrosisSingle-cell RNA sequencingClinical heterogeneityEffective disease-modifying treatmentsPersonalized therapyAnimal modelsComplex pathogenesisEffective treatmentNext-generation sequencingObservational research in epidemic settings: a roadmap to reform
Ricotta E, Carrillo F, Angelli-Nichols S, Barugahare J, Benton A, Carlson C, Chang-Rabley E, Dean N, Duda S, Federer L, Fill M, LeRoy E, Linton N, Lipsitch M, Mathur M, Phelan A, Rid A, Rosen J, Sauer L, Sullivan S, Zendt M, Evans N. Observational research in epidemic settings: a roadmap to reform. BMJ Global Health 2025, 10: e017981. PMID: 39929534, PMCID: PMC11815396, DOI: 10.1136/bmjgh-2024-017981.Peer-Reviewed Original ResearchMeSH KeywordsBiomedical ResearchEpidemicsHumansObservational Studies as TopicPublic HealthResearch DesignData Science and Geriatric Anesthesia Research Opportunity and Challenges
Sandhu M, Tickoo M, Bardia A. Data Science and Geriatric Anesthesia Research Opportunity and Challenges. Clinics In Geriatric Medicine 2025, 41: 101-116. PMID: 39551536, DOI: 10.1016/j.cger.2024.03.009.Peer-Reviewed Original ResearchFour Opportunities To Revitalize The US Biomedical Research Enterprise
Reece E, Balser J, Bibbins-Domingo K, Fraser C, Fried L, Kurth A, Parikh S, Rutta R, Woolley M, Yamamoto K, Zerhouni E, Zoghbi H, Dzau V. Four Opportunities To Revitalize The US Biomedical Research Enterprise. Health Affairs 2025, 44: 140-147. PMID: 39841931, DOI: 10.1377/hlthaff.2024.01001.Peer-Reviewed Original ResearchConceptsNational Academy of Medicine's Vital DirectionsBiomedical research enterpriseReduce health disparitiesHealth equity gapsComplex health issuesNational health outcomesResearch enterpriseFederal research fundingHealth disparitiesResearch fundingWorkforce recruitmentHealth outcomesRetention challengesPromote healthy longevityHealth issuesHealthy longevityVital directionsEquity gapNational Advisory BodyWorkforceNational AcademyPriorityDisparitiesFundingGlobal competition
2024
Practical Guide for Implementing Cryogenic Electron Microscopy Structure Determination in Dermatology Research
Lomakin I, Devarkar S, Freniere C, Bunick C. Practical Guide for Implementing Cryogenic Electron Microscopy Structure Determination in Dermatology Research. Journal Of Investigative Dermatology 2024, 145: 22-31. PMID: 39601740, PMCID: PMC11748023, DOI: 10.1016/j.jid.2024.10.594.Peer-Reviewed Original ResearchStudent Urology Conference Increases Participant Knowledge of Urology Match and Confidence in Research
Kim I, Allu S, Whittelsey M, Kent V, Onal E, Nguyen C, Haleblian G, Kim I, Hyams E, Wu H, Caldamone A, Pareek G. Student Urology Conference Increases Participant Knowledge of Urology Match and Confidence in Research. Urology 2024, 197: 242-249. PMID: 39547277, DOI: 10.1016/j.urology.2024.11.002.Peer-Reviewed Original ResearchMeSH KeywordsBiomedical ResearchCareer ChoiceCongresses as TopicHumansStudents, MedicalUnited StatesUrologyConceptsUrologic subspecialtiesUrology MatchMedical studentsUrology facultyUS medical schoolsUrologyMedical schoolsSurgical skillsAssociated with increased knowledgeFaculty membersUrological conferencesClinical rotationsSubspecialtyAssess student perspectivesPresentationCareer decision-makingUS regionsStudent perspectivesIncreased comfortFaculty panelFellow studentsStudent postersResearch Priorities in Pediatric Asthma Morbidity: Addressing the Impacts of Systemic Racism on Children with Asthma in the United States. An Official American Thoracic Society Workshop Report
Lovinsky-Desir S, Riley I, Bryant-Stephens T, De Keyser H, Forno E, Kozik A, Louisias M, Matsui E, Sheares B, Thakur N, Apter A, Beck A, Bentley-Edwards K, Berkowitz C, Braxton C, Dean J, Jones C, Koinis-Mitchell D, Okelo S, Taylor-Cousar J, Teach S, Wechsler M, Gaffin J, Federico M. Research Priorities in Pediatric Asthma Morbidity: Addressing the Impacts of Systemic Racism on Children with Asthma in the United States. An Official American Thoracic Society Workshop Report. Annals Of The American Thoracic Society 2024, 21: 1349-1364. PMID: 39352175, PMCID: PMC11451894, DOI: 10.1513/annalsats.202407-767st.Peer-Reviewed Original ResearchConceptsImpact of systemic racismAsthma morbidityChildhood asthmaSocial determinants of healthAsthma health outcomesPediatric asthma morbidityDeterminants of healthSystemic racismCommunity engagementDrivers of disparitiesEmergency department visitsResearch teamChildhood asthma outcomesImpact of interventionsMultidisciplinary research teamEffects of systemic racismInnovative study designsImpact of racismAsthma disparitiesSocial determinantsHealthcare accessAsthma outcomesHealth outcomesDepartment visitsEvaluate interventionsPostinfectious Pulmonary Complications: Establishing Research Priorities to Advance the Field: An Official American Thoracic Society Workshop Report.
Auld S, Sheshadri A, Alexander-Brett J, Aschner Y, Barczak A, Basil M, Cohen K, Dela Cruz C, McGroder C, Restrepo M, Ridge K, Schnapp L, Traber K, Wunderink R, Zhang D, Ziady A, Attia E, Carter J, Chalmers J, Crothers K, Feldman C, Jones B, Kaminski N, Keane J, Lewinsohn D, Metersky M, Mizgerd J, Morris A, Ramirez J, Samarasinghe A, Staitieh B, Stek C, Sun J, Evans S. Postinfectious Pulmonary Complications: Establishing Research Priorities to Advance the Field: An Official American Thoracic Society Workshop Report. Annals Of The American Thoracic Society 2024, 21: 1219-1237. PMID: 39051991, DOI: 10.1513/annalsats.202406-651st.Peer-Reviewed Original ResearchMeSH KeywordsBiomedical ResearchCOVID-19HumansLung DiseasesRespiratory Tract InfectionsSARS-CoV-2Societies, MedicalUnited StatesConceptsPulmonary infectionTreatment of pulmonary infectionsLower respiratory tract infectionsLong-term morbidityRespiratory tract infectionsShort-term outcomesAberrant host responseBurden of morbidityReview potential mechanismsPulmonary complicationsTract infectionsPulmonary pathogensSevere acute respiratory syndrome coronavirus 2Acute respiratory syndrome coronavirus 2Causative pathogenRespiratory syndrome coronavirus 2Therapeutic strategiesSyndrome coronavirus 2Host responseInfectionMorbidityPotential mechanismsCoronavirus 2Public perspectives on increased data sharing in health research in the context of the 2023 National Institutes of Health Data Sharing Policy
de Rivera S, Creber R, Zhao Y, Eslami S, Mangal S, Dugdale L, Turchioe M. Public perspectives on increased data sharing in health research in the context of the 2023 National Institutes of Health Data Sharing Policy. PLOS ONE 2024, 19: e0309161. PMID: 39197051, PMCID: PMC11357082, DOI: 10.1371/journal.pone.0309161.Peer-Reviewed Original ResearchConceptsNational Institutes of HealthHealthcare providersEnglish-speaking US adultsNational Institutes of Health policyNational InstitutePatient perspectivePotential unintended consequencesInstitutes of HealthUS adultsHealth researchPatient autonomyBlack participantsPatients' willingnessSexual healthParticipants' perspectivesParticipants' preferencesAfrican AmericansResearch fundersHealthRacial differencesOnline surveyParticipantsHealthcareEffective JanuaryHealth technology companiesPrivacy-Enhancing Technologies in Biomedical Data Science
Cho H, Froelicher D, Dokmai N, Nandi A, Sadhuka S, Hong M, Berger B. Privacy-Enhancing Technologies in Biomedical Data Science. Annual Review Of Biomedical Data Science 2024, 7: 317-343. PMID: 39178425, PMCID: PMC11346580, DOI: 10.1146/annurev-biodatasci-120423-120107.Peer-Reviewed Original ResearchMeSH KeywordsBiomedical ResearchComputer SecurityConfidentialityData ScienceHumansInformation DisseminationPrivacyConceptsPrivacy-enhancing technologiesAdoption of privacy-enhancing technologiesBiomedical data scienceData scienceAnalyze sensitive dataBiomedical data repositoriesPrivacy protectionSensitive dataPrivacy concernsData silosProtect privacyHuman subject dataBiomedical domainData repositoriesPrivacySubjective dataConventional frameworkPriorities for Clinical Research in Pediatric Extracorporeal Membrane Oxygenation Anticoagulation From the Pediatric Extracorporeal Membrane Oxygenation Anticoagulation CollaborativE Consensus Conference
Muszynski J, Bembea M, Gehred A, Lyman E, Cashen K, Cheifetz I, Dalton H, Himebauch A, Karam O, Moynihan K, Nellis M, Ozment C, Raman L, Rintoul N, Said A, Saini A, Steiner M, Thiagarajan R, Watt K, Willems A, Zantek N, Barbaro R, Steffen K, Vogel A, Alexander P, Alexander P, Bembea M, Cashen K, Cheifetz I, Dalton H, Himebauch A, Karam O, Moynihan K, Nellis M, Ozment C, Raman L, Rintoul N, Said A, Saini A, Steiner M, Thiagarajan R, Watt K, Willems A, Zantek N, Barbaro R, Steffen K, Vogel A, Almond C, Anders M, Annich G, Brandão L, Chandler W, Delaney M, DiGeronimo R, Emani S, Gadepalli S, Garcia A, Haileselassie B, Himebauch A, Hyslop R, Kneyber M, Kreuziger L, Le J, Loftis L, McMichael A, McMullan D, Monagle P, Nicol K, Paden M, Patregnani J, Priest J, Raffini L, Ryerson L, Sloan S, Teruya J, Yates A, Gehred A, Lyman E, Muszynski J. Priorities for Clinical Research in Pediatric Extracorporeal Membrane Oxygenation Anticoagulation From the Pediatric Extracorporeal Membrane Oxygenation Anticoagulation CollaborativE Consensus Conference. Pediatric Critical Care Medicine 2024, 25: e78-e89. PMID: 38959362, PMCID: PMC11216398, DOI: 10.1097/pcc.0000000000003488.Peer-Reviewed Original ResearchMeSH KeywordsAnticoagulantsBiomedical ResearchChildChild, PreschoolCritical IllnessExtracorporeal Membrane OxygenationHumansInfantInfant, NewbornConceptsExtracorporeal membrane oxygenationCritically ill neonatesIll neonatesExtracorporeal membrane oxygenation anticoagulationManagement of extracorporeal membrane oxygenationConsensus conferenceSystematic reviewSystematic review of MEDLINECochrane Library databasesReview of MEDLINECare of neonatesMembrane oxygenationChild Health and Nutrition Research Initiative methodologyHemostasis managementLibrary databasesNeonatesConsensus statementClinical recommendationsAnticoagulationClinical careClinical researchEmbaseCochraneExpert panelPediatricAltmetric Attention Scores and Citations of Published Research With or Without Preprints
Zissette S, Gautam A, Krumholz H, Ross J, Wallach J. Altmetric Attention Scores and Citations of Published Research With or Without Preprints. JAMA Network Open 2024, 7: e2424732. PMID: 39058492, PMCID: PMC11282438, DOI: 10.1001/jamanetworkopen.2024.24732.Peer-Reviewed Original ResearchEvaluating the National Institutes of Health Pipeline for Resuscitation Science Investigators
Coute R, Huebinger R, Perman S, Del Rios M, Kurz M. Evaluating the National Institutes of Health Pipeline for Resuscitation Science Investigators. Journal Of The American Heart Association 2024, 13: e035854. PMID: 38879460, PMCID: PMC11255749, DOI: 10.1161/jaha.124.035854.Peer-Reviewed Original ResearchImpact of COVID-19 pandemic on physician-scientist trainees to faculty one year into the pandemic
Obradovic A, Toubat O, Chen N, Siebert A, Jansen C, Christophers B, Leveille E, Noch E, Kwan J. Impact of COVID-19 pandemic on physician-scientist trainees to faculty one year into the pandemic. BMC Medical Education 2024, 24: 587. PMID: 38807106, PMCID: PMC11134762, DOI: 10.1186/s12909-024-05541-9.Peer-Reviewed Original ResearchConceptsPersonal healthLong-term effects of COVID-19Physician-scientist traineesPhysician-scientistsCross-sectional survey of medical studentsCOVID-19 pandemicSurvey of medical studentsClustering techniqueScientific pursuitsHealth of familiesMultivariate regression analysisEffects of COVID-19ConclusionsThis national surveyLevel of trainingTailored supportPhysician-scientist trainingResearch productivityMental healthFewer physiciansLonger-term impactMedical studentsImpaired productionCOVID-19Long-term effectsReport concerns
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