2025
The landscape of suicide risk factors in Latin America
Cabrera-Mendoza B, Fries G, Polimanti R, Consortium S. The landscape of suicide risk factors in Latin America. Psychiatry Research 2025, 351: 116597. DOI: 10.1016/j.psychres.2025.116597.Peer-Reviewed Original ResearchLatin AmericaMental health care accessSocial determinants of suicideDevelopment of tailored interventionsCare-seeking behaviorHealth care accessSuicide ratesRisk factorsSuicide prevention strategiesTraditional gender normsMiddle-income countriesReduce suicide ratesCare accessSocial determinantsSuicide risk factorsTailored interventionsDeterminants of suicideImpact of religiosityGender normsFamily tiesLatin American populationsPrevention strategiesSignificant disparitiesSociocultural factorsLatinSocial Determinants Associated with Diabetic Retinopathy Awareness: National Health and Nutrition Examination Survey (2005-2008)
Nwanyanwu K, Andoh J, Chen E, Xu Y, Granados A, Deng Y, Desai M, Nunez-Smith M. Social Determinants Associated with Diabetic Retinopathy Awareness: National Health and Nutrition Examination Survey (2005-2008). American Journal Of Ophthalmology 2025 PMID: 40550446, DOI: 10.1016/j.ajo.2025.06.028.Peer-Reviewed Original ResearchSocial determinants of healthSocial determinants of health variablesAwareness of DRAdverse SDHNational Health and Nutrition Examination SurveyNon-Hispanic Black participantsHealth and Nutrition Examination SurveyRao-Scott chi-square testsDeterminants of healthSocial Support IndexNutrition Examination SurveyDiabetic retinopathyAssociated with awarenessAwareness of diabetic retinopathyMultivariate logistic regressionDepression screeningSocial determinantsPHQ-9Fundus photographyExamination SurveyUnited StatesSociodemographic factorsChi-square testRao-ScottDR awareness975-P: Housing Status and Glucose Variability in Type 2 Diabetes
NAM S, LEE M, WHITTEMORE R, ASH G, JEON S, DOMÍNGUEZ NAVARRO A, WEINZIMER S. 975-P: Housing Status and Glucose Variability in Type 2 Diabetes. Diabetes 2025, 74 DOI: 10.2337/db25-975-p.Peer-Reviewed Original ResearchStable housingHousing statusType 2 diabetesSocial determinants of healthHousing instabilityDeterminants of healthImprove diabetes managementGlucose variabilitySocial determinantsDiabetes outcomesContinuous glucose monitoringUnstable housingPost hoc comparisonsDiabetes managementDemographic surveyTime Below RangeJ indexTIR levelsLower TIRCoefficient of variationTime-in-rangeGV parametersPost-hocHypoglycemic exposureIndividualsSocial Determinants of Health and Healthcare Utilization in Infants With Bronchopulmonary Dysplasia
Urbach H, Ostfeld‐Johns S, McCollum S, Weiss P, Kandil S, Brumer E. Social Determinants of Health and Healthcare Utilization in Infants With Bronchopulmonary Dysplasia. Pediatric Pulmonology 2025, 60: e71153. PMID: 40504047, DOI: 10.1002/ppul.71153.Peer-Reviewed Original ResearchConceptsSocial determinants of healthChildhood Opportunity IndexArea Deprivation IndexHealthcare utilizationED visitsImpact of social determinants of healthSocial determinants of health variablesInfluence of social determinants of healthEmergency departmentAssociated with fewer ED visitsAssociated with increased ED visitsHigh-deprivation neighborhoodsDeterminants of healthBronchopulmonary dysplasiaAdverse health outcomesMediation analysisDeprivation indexHealthcare useSocial determinantsNo significant associationHealth outcomesFollow-upHospital utilizationNeighborhood disadvantageRacial/ethnic differencesDeveloping programme theory for a place-based, systems change approach to adolescent mental health: A developmental realist evaluation
Allen K, March A, Alexandrescu B, Harris J, Stemp R, Li S, Kennedy L, Davies K, Malhotra T, Santana de Lima E, Hobbs T, Rehill N, Shand J, Fonagy P, Pilling S, Berry V. Developing programme theory for a place-based, systems change approach to adolescent mental health: A developmental realist evaluation. PLOS Mental Health 2025, 2: e0000226. DOI: 10.1371/journal.pmen.0000226.Peer-Reviewed Original ResearchAdolescent mental healthProgramme theoryMental healthInitial programme theoryYoung People's Advisory GroupEvidence-informed strategiesPlace-based initiativesSystems change approachImpact evaluationSocial determinantsRealist reviewRealist evaluationFocus groupsAdvisory GroupInformant interviewsPrevention frameworkMechanisms of changeHealthPlace-based approachWellbeingContextual driversProgrammeInterviewsTheory generationPlace-basedIdentifying multi-level social determinants for disparities in survival and patient-reported outcomes in national head and neck cancer trials.
Bai J, Borges M, Nguyen-Tan F, Rosenthal D, Caudell J, Gillison M, Mell L, Bruner D, Yeager K, Eldridge R, Thorstad W, Xu M, Medek S, Echevarria M, Awan M, Shin D, Pugh S, Yom S. Identifying multi-level social determinants for disparities in survival and patient-reported outcomes in national head and neck cancer trials. Journal Of Clinical Oncology 2025, 43: 11066-11066. DOI: 10.1200/jco.2025.43.16_suppl.11066.Peer-Reviewed Original ResearchSocial determinants of healthArea-level social determinants of healthQoL declineTravel burdenDesigning community-based interventionsHead and neck cancerOdds ratioHazard ratioNeighborhood socioeconomic deprivationDeterminants of healthCommunity-based interventionsConfidence intervalsLogistic regression assessed associationsImprove cancer outcomesPatient's zip codeCox proportional hazards regressionPatient-reported outcomesMultivariable Cox proportional hazards regressionProportional hazards regressionSocioeconomic deprivationSocial determinantsHead and neck cancer trialsNon-HispanicCancer outcomesZip codesPrognostic and Predictive Insights From Genomic Assays for Breast Cancer in Diverse Populations
Abdou Y, Kantor O, Racz J, Newman L, Pierce L, Winer E. Prognostic and Predictive Insights From Genomic Assays for Breast Cancer in Diverse Populations. JAMA Oncology 2025, 11: 655-663. PMID: 40178824, DOI: 10.1001/jamaoncol.2025.0178.Peer-Reviewed Original ResearchConceptsEthnic disparitiesBreast cancer mortality ratesBreast cancerGenomic assaysCancer mortality ratesBiological characteristics of tumorsPredictive valueDiverse populationsGenomic assay resultsBreast cancer outcomesPersonalized clinical decision-makingBasal-like subtypeAggressive tumor phenotypeBreast cancer recurrenceCharacteristics of tumorsRandomized clinical trialsEthnic groupsSocial determinantsClinical decision-makingMultigene assaysLuminal BCancer outcomesDistribution of risk estimatesSurvival outcomesMolecular subtypesImpact of age on financial toxicity among breast cancer patients with resectable invasive breast cancer: A systematic review.
Myers S, Morton C, Bain P, Obeng-Gyasi S, Paskett E, McAlearney A, Greenup R, Minami C, Mittendorf E, King T. Impact of age on financial toxicity among breast cancer patients with resectable invasive breast cancer: A systematic review. Journal Of Clinical Oncology 2025, 43 DOI: 10.1200/jco.2025.43.16_suppl.e23194.Peer-Reviewed Original ResearchCancer-related costsFinancial toxicitySystematic reviewInvasive breast cancerSocial determinants of healthBreast cancerSymptoms of breast cancerBlood Institute assessment toolIncidence of breast cancerOutcome metricsPatient-reported outcome metricsStage I-III breast cancerDeterminants of healthI-III breast cancerNon-metastatic invasive breast cancerAffordability of careBreast cancer diagnosisYounger ageYoung adultsInstitute assessment toolEnglish-language articlesHealth disparitiesSocial determinantsTreatment-related expensesWeb of ScienceLeveraging Medical Students’ Experiences with Social Determinants of Health During Their Pediatric Clerkship to Drive Curriculum
Kala S, Johnson R, Phatak U, Fenick A, Goldman M. Leveraging Medical Students’ Experiences with Social Determinants of Health During Their Pediatric Clerkship to Drive Curriculum. Journal Of Medical Education And Curricular Development 2025, 12: 23821205251342079. PMID: 40452893, PMCID: PMC12126650, DOI: 10.1177/23821205251342079.Peer-Reviewed Original ResearchSocial determinants of healthMedical students' experiencesDeterminants of healthSocial determinantsPediatric clerkshipNeeds-assessmentInductive content analysisNegative health outcomesUndergraduate medical educationHealthy peopleHealthcare teamHealth outcomesStudent experienceInsurance statusMedical educationPediatric servicesMedical studentsPublished curriculaClerkship studentsContent analysisClerkshipReflective journal entriesCurricular developmentHealthDepartment of ChildrenOrthopaedic Centers May Require Additional Support to Meet the 2024 TJC and CMS SDOH Requirements
Darby F, Rancu A, Nishime N, Kurek D, Wiznia D. Orthopaedic Centers May Require Additional Support to Meet the 2024 TJC and CMS SDOH Requirements. Orthopaedic Nursing 2025, 44: 184-192. PMID: 40466120, DOI: 10.1097/nor.0000000000001117.Peer-Reviewed Original ResearchConceptsSocial determinants of healthOrthopaedic nursesCenters for Medicare & Medicaid ServicesDeterminants of healthWritten action planScreening requirementsElectronic medical recordsNursing staffSocial determinantsJoint CommissionHealthcare organizationsHospital administratorsMedicaid ServicesNursesSurvey questionsMedical recordsIncreased communicationInstitutional preparednessAction planPreparednessScreeningHealthStaffTJCOrganizational responsesSocial determinants of health extraction from clinical notes across institutions using large language models
Keloth V, Selek S, Chen Q, Gilman C, Fu S, Dang Y, Chen X, Hu X, Zhou Y, He H, Fan J, Wang K, Brandt C, Tao C, Liu H, Xu H. Social determinants of health extraction from clinical notes across institutions using large language models. Npj Digital Medicine 2025, 8: 287. PMID: 40379919, PMCID: PMC12084648, DOI: 10.1038/s41746-025-01645-8.Peer-Reviewed Original ResearchMultimorbidity of mental health and substance use disorders among housed and homeless U.S. veterans
Tsai J, Szymkowiak D, Beydoun H. Multimorbidity of mental health and substance use disorders among housed and homeless U.S. veterans. Scientific Reports 2025, 15: 15185. PMID: 40307423, PMCID: PMC12043799, DOI: 10.1038/s41598-025-99394-x.Peer-Reviewed Original ResearchConceptsMental health disorder diagnosisHomeless veteransMental health disordersEmergency department careHoused veteransSubstance use disordersSocial determinants of mental healthSUD diagnosisDeterminants of mental healthMental healthU.S. Department of Veterans Affairs (VA) healthcare systemDepartment of Veterans Affairs (VA) healthcare systemVeterans Affairs (VA) healthcare systemU.S. veteransHousing instabilityHousing situationComorbid mental health disordersSocial determinantsAdministrative dataHousingPsychiatric epidemiologyHealthcare systemHealth disordersNational cohortVeteransImpact of Social Determinants of Health on Outcomes of Nontraumatic Subarachnoid Hemorrhage
Renedo D, Rivier C, Koo A, Clocchiatti‐Tuozzo S, Huo S, Sujijantarat N, Torres‐Lopez V, Hebert R, Schwamm L, de Havenon A, Gunel M, Matouk C, Falcone G, Sheth K. Impact of Social Determinants of Health on Outcomes of Nontraumatic Subarachnoid Hemorrhage. Journal Of The American Heart Association 2025, 14: e037199. PMID: 40194963, PMCID: PMC12132901, DOI: 10.1161/jaha.124.037199.Peer-Reviewed Original ResearchConceptsSocial determinants of healthSocial deprivation indexDeterminants of healthImpact of social determinants of healthDeprivation indexLength of stayInfluence of social determinants of healthOdds ratioDischarge dispositionHigher social deprivation indexAssociated with reduced oddsAverage length of stayVascular risk factorsAssociated with longer lengthSocial determinantsSignificant health burdenEstimate associationsIn-hospital deathNontraumatic subarachnoid hemorrhageSocioeconomic levelHealth burdenOverall mortality rateDecreased deathRisk factorsHealthAddressing social determinants of health in individuals with mental disorders in clinical practice: review and recommendations
Jeste D, Smith J, Lewis-Fernández R, Saks E, Na P, Pietrzak R, Quinn M, Kessler R. Addressing social determinants of health in individuals with mental disorders in clinical practice: review and recommendations. Translational Psychiatry 2025, 15: 120. PMID: 40180893, PMCID: PMC11968902, DOI: 10.1038/s41398-025-03332-4.Peer-Reviewed Original ResearchConceptsSocial determinants of healthDeterminants of healthSocial determinantsMental disordersSocial determinants of mental healthDeterminants of mental healthQuality of life of personsResponsibility of healthcare providersImplementing such interventionsMedical risk factorsLife of personsRelevant social factorsHealthcare providersClinical psychiatric practicePsychosocial strategiesMental healthCase managementOverall healthPsychiatric cliniciansHealthWell-beingCommunity levelPsychiatric disordersRisk factorsPsychiatric practiceThe Relationship Between Social Determinants of Health and Flourishing Among Medical, Physician Assistant, and Nurse Practitioner Students.
Neary S, Doolittle B, Mueller M, Nichols M. The Relationship Between Social Determinants of Health and Flourishing Among Medical, Physician Assistant, and Nurse Practitioner Students. The Journal Of Physician Assistant Education 2025 PMID: 40168164, DOI: 10.1097/jpa.0000000000000670.Peer-Reviewed Original ResearchSocial determinants of healthDeterminants of healthPhysician assistant/associateNurse practitionersSocial determinantsUnmet social determinants of healthSocial determinants of health needsNurse practitioner studentsCross-sectional designPerson's mental healthAcademic medical centerNurse trainingPhysician assistantsPractitioner studentsNP studentsMental healthSecure Flourish IndexDescriptive statisticsEligible studentsFlourish IndexFood insecuritySurvey questionsMedical CenterNursesChi-squareSocial Determinants of Health and Suicide-Related Outcomes
Na P, Shin J, Kwak H, Lee J, Jester D, Bandara P, Kim J, Moutier C, Pietrzak R, Oquendo M, Jeste D. Social Determinants of Health and Suicide-Related Outcomes. JAMA Psychiatry 2025, 82: 337-346. PMID: 39745761, PMCID: PMC11964833, DOI: 10.1001/jamapsychiatry.2024.4241.Peer-Reviewed Original ResearchSocial determinants of healthSuicide mortalitySuicide-related outcomesAssociation of social determinants of healthRisk of suicide mortalityPrevent suicideAssociated with suicide mortalitySuicidal ideationHomeless individualsMeta-analysesDeterminants of healthSuicide riskRisk factorsPublic health policiesSuicide attemptsIncarcerated female youthIntimate partner violenceSexual minority statusPrevalence of lifetime suicidal ideationIncreased suicide riskExperiences of childhood abuseSocial determinantsWeb of ScienceResearch SynthesesTailored interventionsMultilevel Intervention to Increase Patient Portal Use in Adults With Type 2 Diabetes Who Access Health Care at Community Health Centers: Single Arm, Pre-Post Pilot Study
Whittemore R, Jeon S, Akyirem S, Chen H, Lipson J, Minchala M, Wagner J. Multilevel Intervention to Increase Patient Portal Use in Adults With Type 2 Diabetes Who Access Health Care at Community Health Centers: Single Arm, Pre-Post Pilot Study. JMIR Formative Research 2025, 9: e67293. PMID: 40131327, PMCID: PMC11979536, DOI: 10.2196/67293.Peer-Reviewed Original ResearchConceptsCommunity health centersPatient portal useDigital health literacyPortal useHealth literacyMultilevel interventionsType 2 diabetesSocial determinants of healthDiabetes self-management educationCommunity health workersImprove health equityDeterminants of healthSelf-management educationDiabetes self-efficacyHealth-related outcomesBarriers to clinical integrationPre-post designHemoglobin A<sub>1c</sub> levelDiabetes distressHealth equityPatient portalsSocial determinantsDeliver carePortal accountHealth appsDisparities in Social Determinants of Health Associated With Decreased Likelihood of Receiving Total Joint Arthroplasty.
Kim L, Nishime N, Ansah-Twum J, Grauer J, Wiznia D. Disparities in Social Determinants of Health Associated With Decreased Likelihood of Receiving Total Joint Arthroplasty. Journal Of The American Academy Of Orthopaedic Surgeons 2025 PMID: 40063682, DOI: 10.5435/jaaos-d-24-00945.Peer-Reviewed Original ResearchSocial determinants of healthSocial determinants of health disparitiesIndividual social determinants of healthSocial determinants of health categoriesSocial determinants of health screeningTotal joint arthroplastyFinancial strainDeterminants of healthSpecialized health careDiagnosis of kneeRates of total joint arthroplastyMultivariate logistic regressionTransportation insecuritySocial determinantsOrthopaedic careHealth careKnee osteoarthritisHip OAOrthopaedic conditionsDecreased oddsHip osteoarthritisLogistic regressionFood insecurityDisparitiesKneeW59 Understanding Homelessness Experiences and Social Determinants of Health Among People Experiencing Homelessness Enrolled in Methadone Treatment
Gazzola M, Baylen C, Saeed G, Hoffman K, Thompson E, Madden L, Eggert K, Beitel M, Barry D. W59 Understanding Homelessness Experiences and Social Determinants of Health Among People Experiencing Homelessness Enrolled in Methadone Treatment. Drug And Alcohol Dependence 2025, 267: 112001. DOI: 10.1016/j.drugalcdep.2024.112001.Peer-Reviewed Original ResearchP-1415. Social Determinants of Health and Side Effects Significantly Predict Pre-Exposure Prophylaxis (PrEP) Preferences for Every 2 Month Long-Acting Injectable vs. Daily Oral PrEP among Cisgender Women in the United States and the Dominican Republic
Kerrigan D, Scott R, O’Rourke A, Galai N, Karver T, Davis W, Metzner A, Oglesby A, Moriarty P, Taggart T, Barrington C, Gomez H, Perez M, Donastorg Y. P-1415. Social Determinants of Health and Side Effects Significantly Predict Pre-Exposure Prophylaxis (PrEP) Preferences for Every 2 Month Long-Acting Injectable vs. Daily Oral PrEP among Cisgender Women in the United States and the Dominican Republic. Open Forum Infectious Diseases 2025, 12: ofae631.1590. PMCID: PMC11777370, DOI: 10.1093/ofid/ofae631.1590.Peer-Reviewed Original ResearchPre-exposure prophylaxisLong-actingFemale sex workersSocial determinantsCisgender womenSocial determinants of healthHIV diagnosis ratesDaily oral PrEPDeterminants of healthBlack cisgender womenLow pre-exposure prophylaxisCross-sectional surveyOral PrEPUnited StatesHIV disparitiesWhite cisgender womenHIV inequitiesSide effectsIncreased oddsDiagnosis rateHIVPrEP preferencesDominican RepublicPrEPSex workers
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