2025
Association of delayed asthma diagnosis with asthma exacerbations in children
Wi C, Ryu E, King K, Kwon J, Bublitz J, Park M, Chiarella S, Greenwood J, Pongdee T, Myers L, Nordlund B, Sohn S, Sagheb E, Kshatriya B, Watson D, Liu H, Sheares B, Davis C, Schulz W, Juhn Y. Association of delayed asthma diagnosis with asthma exacerbations in children. Journal Of Allergy And Clinical Immunology Global 2025, 4: 100409. PMID: 40008091, PMCID: PMC11851198, DOI: 10.1016/j.jacig.2025.100409.Peer-Reviewed Original ResearchElectronic health recordsDiagnosis of asthmaAsthma diagnosisAsthma exacerbationsRisk of AEPredetermined Asthma CriteriaDiagnosis of childhood asthmaChildhood asthma managementIncreased riskCox proportional hazards modelsIncreased risk of AECare qualityAsthma outcomesHealth recordsProportional hazards modelAsthma managementChildhood asthmaBirth cohortAsthma severityDiagnosis statusIndex dateIdentifying childrenPrimary outcomeNatural language processing algorithmsHazards modelIdentifying Metabolic Dysfunction-Associated Steatotic Liver Disease Using Natural Language Processing in a US National Cohort.
John B, Bastaich D, Mezzacappa C, Ferreira R, Hentschel A, Samos A, Mahmud N, Taddei T, Kaplan D, Serper M, Dahman B. Identifying Metabolic Dysfunction-Associated Steatotic Liver Disease Using Natural Language Processing in a US National Cohort. The American Journal Of Gastroenterology 2025 PMID: 39950372, DOI: 10.14309/ajg.0000000000003321.Peer-Reviewed Original ResearchElectronic health recordsCardiometabolic risk factorsAlcohol useChart reviewRetrospective study of participantsStudy of participantsLiver diseaseSteatotic liver diseaseIncreased alcohol intakeEligible veteransICD-9/10 codesHealth recordsNational cohortAlcohol intakeEvidence of hepatic steatosisEpidemiological studiesNatural language processing algorithmsRisk factorsStudy cohortOutcome studiesVeteransCohortClinical entityRetrospective studyMetabolic dysfunction
2024
Natural Language Processing to Identify Infants Aged 90 Days and Younger With Fevers Prior to Presentation.
Aronson P, Kuppermann N, Mahajan P, Nielsen B, Olsen C, Meeks H, Grundmeier R. Natural Language Processing to Identify Infants Aged 90 Days and Younger With Fevers Prior to Presentation. Hospital Pediatrics 2024, 15: e1-e5. PMID: 39679596, PMCID: PMC12163744, DOI: 10.1542/hpeds.2024-008051.Peer-Reviewed Original ResearchElectronic health recordsEmergency departmentNatural language processing algorithmsElectronic health record dataPediatric Emergency Care Applied Research Network RegistryFebrile infantsNatural language processingCross-sectional studyTrauma-related diagnosesPositive predictive valueHealth recordsHealth systemDocumented feverClinical notesPre-EDNetwork registryCohort identificationVisitsLanguage processingNLP algorithmsPredictive valueInfantsFeverResearch studiesPrevalent Atherosclerotic Cardiovascular Disease Among Veterans by Sexual Orientation
Streed C, Duncan M, Heier K, Workman T, Beach L, Caceres B, O'Leary J, Skanderson M, Goulet J. Prevalent Atherosclerotic Cardiovascular Disease Among Veterans by Sexual Orientation. Journal Of The American Heart Association 2024, 13: e036898. PMID: 39508159, PMCID: PMC11681393, DOI: 10.1161/jaha.124.036898.Peer-Reviewed Original ResearchPrevalent atherosclerotic cardiovascular diseasesAtherosclerotic cardiovascular diseaseIndex dateCardiovascular diseaseVeterans Health Administration dataPoor cardiovascular healthHealth administrative dataPrimary care appointmentsLGB veteransCardiovascular risk factorsCare appointmentsLogistic regression analysisSexual orientationCardiovascular healthVeteran populationHispanic ethnicityAdministrative dataNationwide cohortVeteransBaseline dateNatural language processing algorithmsSubstance useRisk factorsRegression analysisLanguage processing algorithmsBoneScore: A natural language processing algorithm to extract bone mineral density data from DXA scans
Fodeh S, Wang R, Murphy T, Kidwai-Khan F, Leo-Summers L, Tessier-Sherman B, Hsieh E, Womack J. BoneScore: A natural language processing algorithm to extract bone mineral density data from DXA scans. Health Informatics Journal 2024, 30: 14604582241295930. PMID: 39526751, PMCID: PMC11872221, DOI: 10.1177/14604582241295930.Peer-Reviewed Original ResearchConceptsT-score valuesT-scoreNLP algorithmsDXA scansFemoral neck T-scoreNatural language processing algorithmsBone mineral density dataLanguage processing algorithmsBone mineral densityExtract annotationsRegular expressionsTest dataProcessing algorithmsDXA reportsMineral densityAlgorithmMultivariate linear regressionClinical face validityRisk factorsPresence of informationDXANLPClinical validationClinical expertsAccuracyA Case Demonstration of the Open Health Natural Language Processing Toolkit From the National COVID-19 Cohort Collaborative and the Researching COVID to Enhance Recovery Programs for a Natural Language Processing System for COVID-19 or Postacute Sequelae of SARS CoV-2 Infection: Algorithm Development and Validation
Wen A, Wang L, He H, Fu S, Liu S, Hanauer D, Harris D, Kavuluru R, Zhang R, Natarajan K, Pavinkurve N, Hajagos J, Rajupet S, Lingam V, Saltz M, Elowsky C, Moffitt R, Koraishy F, Palchuk M, Donovan J, Lingrey L, Stone-DerHagopian G, Miller R, Williams A, Leese P, Kovach P, Pfaff E, Zemmel M, Pates R, Guthe N, Haendel M, Chute C, Liu H, Collaborative C, Initiative T. A Case Demonstration of the Open Health Natural Language Processing Toolkit From the National COVID-19 Cohort Collaborative and the Researching COVID to Enhance Recovery Programs for a Natural Language Processing System for COVID-19 or Postacute Sequelae of SARS CoV-2 Infection: Algorithm Development and Validation. JMIR Medical Informatics 2024, 12: e49997. PMID: 39250782, PMCID: PMC11420592, DOI: 10.2196/49997.Peer-Reviewed Original ResearchNatural language processingNatural language processing algorithmsNatural language processing toolkitNatural language processing systemsProcessing toolkitNatural language processing tasksUnified Medical Language SystemClinical natural language processingAlgorithm developmentMedical Language SystemLanguage processing systemDevelopment approachNLP tasksTime-critical natureHuman expertsNatural language processing resultsExpert annotationsLanguage processingTraining setClinical narrativesNatural language processing extractsTest setAlgorithmPostacute sequelae of SARS-CoV-2 infectionProcessing systemIdentification of hepatic steatosis among persons with and without HIV using natural language processing
Torgersen J, Skanderson M, Kidwai-Khan F, Carbonari D, Tate J, Park L, Bhattacharya D, Lim J, Taddei T, Justice A, Re V. Identification of hepatic steatosis among persons with and without HIV using natural language processing. Hepatology Communications 2024, 8: e0468. PMID: 38896066, PMCID: PMC11186806, DOI: 10.1097/hc9.0000000000000468.Peer-Reviewed Original ResearchConceptsImaging ReportingSteatotic liver diseaseHIV statusHepatic steatosisPrevalence of metabolic comorbiditiesImaging studiesVeterans Aging Cohort StudyCompare patient characteristicsPositive predictive valueAlcohol use disorderAging Cohort StudyIdentification of hepatic steatosisHIV infectionHepatitis BMetabolic comorbiditiesNatural language processing algorithmsRadiological studiesCohort studyPatient characteristicsClinical reviewLiver diseaseHIVPredictive valueUse disorderClinical image reportsA roadmap to artificial intelligence (AI): Methods for designing and building AI ready data to promote fairness
Kidwai-Khan F, Wang R, Skanderson M, Brandt C, Fodeh S, Womack J. A roadmap to artificial intelligence (AI): Methods for designing and building AI ready data to promote fairness. Journal Of Biomedical Informatics 2024, 154: 104654. PMID: 38740316, PMCID: PMC11144439, DOI: 10.1016/j.jbi.2024.104654.Peer-Reviewed Original ResearchArtificial intelligenceMachine learningNatural language processing techniquesRaw dataLife cycle of dataLanguage processing techniquesInput dataApplication of artificial intelligenceArtificial intelligence processesMachine learning algorithmsTransform raw dataNatural language processing algorithmsArtificial intelligence methodsApplication of AILanguage processing algorithmsLearning algorithmsIntelligent processingError rateIntelligence methodsData governanceProcessing algorithmsData expertiseAlgorithmic biasElectronic health record dataData frameworks
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