2025
Moving Beyond Desensitization to Tolerance in Food Allergy
Flom J, Shreffler W, Perrett K. Moving Beyond Desensitization to Tolerance in Food Allergy. The Journal Of Allergy And Clinical Immunology In Practice 2025, 13: 741-744. PMID: 40010566, DOI: 10.1016/j.jaip.2025.02.014.Peer-Reviewed Original ResearchManagement of IgE-mediated food allergyFood allergyIgE-mediated food allergyStages of clinical developmentSide effect profileMode of deliveryGoal of therapeuticsSustained unresponsivenessDosing regimensDose protocolProactive therapyAllergen-specificClinical developmentActive therapyPatient populationSide effectsTherapyPassive therapyPatient-specificDesensitizationClinical contextPatientsDoseAllergyDegree of protection
2024
Accuracy of Spanish and English-generated ChatGPT responses to commonly asked patient questions about labor epidurals: a survey-based study among bilingual obstetric anesthesia experts
Gonzalez Fiol A, Mootz A, He Z, Delgado C, Ortiz V, Reale S. Accuracy of Spanish and English-generated ChatGPT responses to commonly asked patient questions about labor epidurals: a survey-based study among bilingual obstetric anesthesia experts. International Journal Of Obstetric Anesthesia 2024, 61: 104290. PMID: 39579604, DOI: 10.1016/j.ijoa.2024.104290.Peer-Reviewed Original ResearchLabor epiduralsNon-English-speaking patientsMode of deliveryHealth inequalitiesLabor courseCesarean deliveryObstetric anesthesiologistPatient questionsSurvey-based studyMedian scoreMedical adviceAnesthesia expertsEpiduralsLikert scaleEnglishLanguage modelEnglish answersPerpetuate misinformationPatientsLanguageSpanishScoresAccuracy scoresDeliveryQuestionsThe Potential Therapeutic Effects of Botulinum Neurotoxins on Neoplastic Cells: A Comprehensive Review of In Vitro and In Vivo Studies
Safarpour D, Tavassoli F, Jabbari B. The Potential Therapeutic Effects of Botulinum Neurotoxins on Neoplastic Cells: A Comprehensive Review of In Vitro and In Vivo Studies. Toxins 2024, 16: 355. PMID: 39195765, PMCID: PMC11358967, DOI: 10.3390/toxins16080355.Peer-Reviewed Original ResearchIn vivo studiesNeoplastic cellsReview of in vitroBotulinum neurotoxinBotulinum toxinMode of deliveryAnti-neoplastic treatmentProgression of cancer cellsIn vivo deliveryAnti-neoplastic potentialIn vitro effectsPotential therapeutic effectsNon-neuronal cellsNeoplastic cell linesHigh dosesTherapeutic effectCancer cellsClostridium difficileControlled studiesApoptotic effectsCell linesDisruption of cell membranesPrimary neuronsSystematic reviewCell cytoplasmPerinatal outcomes are similar in programmed and modified natural frozen embryo transfer cycles
Farrell A, Yuen M, Dodge L, Sakkas D, Vaughan D, Toth T. Perinatal outcomes are similar in programmed and modified natural frozen embryo transfer cycles. Reproductive BioMedicine Online 2024, 49: 104347. PMID: 39213983, DOI: 10.1016/j.rbmo.2024.104347.Peer-Reviewed Original ResearchFrozen embryo transfer cyclesEmbryo transfer cyclesIschemic placental diseasePreterm deliveryPerinatal outcomesPlacental diseaseTransfer cyclesIncreased risk of cesarean deliveryRisk of ischemic placental diseaseIncreased riskRisk of cesarean deliveryNatural FET cyclesIntrauterine growth restrictionNeonatal clinical outcomesModified natural cycleRetrospective cohort studyMode of deliveryCesarean deliverySGA infantsGestational ageFET cyclesGrowth restrictionClinical outcomesCohort studyPatientsExploring Effect of Patient Counseling on Mode of Delivery After Cesarean Section [ID 2683575]
Pondugula N, Greenberg J, Illuzzi J, Adeyemo O. Exploring Effect of Patient Counseling on Mode of Delivery After Cesarean Section [ID 2683575]. Obstetrics And Gynecology 2024, 143: 54s-54s. DOI: 10.1097/01.aog.0001013692.09625.74.Peer-Reviewed Original ResearchCesarean delivery rateBody mass indexMode of deliveryVaginal deliveryNational cesarean delivery rateHistory of VBACIncreasing vaginal birthEffect of patient counselingHistory of vaginal deliveryIncreased BMIDelivery rateVBAC ratesVaginal birthTOLACVBACAntepartum counselingCesarean deliveryAssociated with ageDocumented counselingObstetric dataCounseling documentationMedicaid insuranceInsurance typeInclusion criteriaMass indexNeonatal Outcomes Are Similar between Patients with Resolved and Those with Persistent Oligohydramnios
Whelan A, Has P, Savitz D, Danilack V, Lewkowitz A. Neonatal Outcomes Are Similar between Patients with Resolved and Those with Persistent Oligohydramnios. American Journal Of Perinatology 2024, 41: 1285-1289. PMID: 38423121, PMCID: PMC11223946, DOI: 10.1055/a-2278-8948.Peer-Reviewed Original ResearchFetal growth restrictionPersistent oligohydramniosNeonatal resuscitationGestational ageGrowth restrictionWomen meeting study criteriaContinuous positive airway pressureTrained research nursesDiagnosis of oligohydramniosPositive airway pressureMode of deliveryBag-mask ventilationTime of deliveryRetrospective cohort studyTertiary-care hospitalResearch nursesAdministration of oxygenMedication administrationNICU admissionSingleton gestationsNeonatal outcomesPerinatal outcomesHypertensive disordersNeonatal informationPrenatal ultrasound
2023
Focus Group Study of Heart Failure Nurses’ Perceptions of the Feasibility of Cognitive Behavioral Therapy for Insomnia
O’Connell M, Feder S, Nwanaji-Enwerem U, Redeker N. Focus Group Study of Heart Failure Nurses’ Perceptions of the Feasibility of Cognitive Behavioral Therapy for Insomnia. Nursing Research 2023, 73: 109-117. PMID: 37967228, PMCID: PMC10922255, DOI: 10.1097/nnr.0000000000000706.Peer-Reviewed Original ResearchCognitive behavioral therapyHeart failureMode of deliveryBehavioral therapyClinical settingEfficacious treatmentOutpatient HF clinicOutpatient clinical settingAdvanced practice nursesDescriptive qualitative study designPerceptions of nursesImportance of insomniaHF clinicQualitative study designPractice nursesNurse membersDaytime consequencesSleep specialistsFocus groupsNurses' perceptionsSleep healthInsomniaTherapyFocus group participantsFocus group studyGene-Environment Analyses Reveal Novel Genetic Candidates with Prenatal Tobacco Exposure in Relation to Risk for Childhood Acute Lymphoblastic Leukemia.
Zhong C, Li S, Arroyo K, Morimoto L, de Smith A, Metayer C, Ma X, Kogan S, Gauderman W, Wiemels J. Gene-Environment Analyses Reveal Novel Genetic Candidates with Prenatal Tobacco Exposure in Relation to Risk for Childhood Acute Lymphoblastic Leukemia. Cancer Epidemiology Biomarkers & Prevention 2023, 32: 1707-1715. PMID: 37773025, PMCID: PMC11812055, DOI: 10.1158/1055-9965.epi-23-0258.Peer-Reviewed Original ResearchConceptsMaternal tobacco exposureAcute lymphoblastic leukemiaChildhood acute lymphoblastic leukemiaTobacco exposureLymphoblastic leukemiaLarge population-based studyPopulation-based studyEffects of tobaccoPrenatal tobacco exposureAryl hydrocarbon receptor repressor geneMode of deliverySelf-reported smokingIndividual-level risk factorsGenetic variantsPolygenetic risk scoresYear of birthAHRR hypomethylationSubsequent childhoodMaternal exposureGestational ageRisk factorsTobacco smokeRisk scoreBiological markersBlood spotsMaternal and Delivery Characteristics and Self-Reported Perceived Control During Labor
Mallett G, Hill K, Doherty L, Grobman W, Reddy U, Tita A, Silver R, Rice M, El-Sayed Y, Wapner R, Rouse D, Saade G, Thorp J, Chauhan S, Costantine M, Chien E, Casey B, Srinivas S, Swamy G, Simhan H, Macones G. Maternal and Delivery Characteristics and Self-Reported Perceived Control During Labor. Obstetrics And Gynecology 2023, 142: 117-124. PMID: 37290106, PMCID: PMC10330140, DOI: 10.1097/aog.0000000000005230.Peer-Reviewed Original ResearchConceptsBody mass indexWeeks of gestationLabor Agentry ScaleScale scoreLabor painPrivate health insuranceDelivery characteristicsLabor pain scoresPrevious pregnancy lossSpontaneous vaginal deliverySevere neonatal complicationsHealth insuranceMode of deliveryFinal multivariable modelMultivariable linear regressionSelf-administered questionnaireSelf-reported raceNeonatal complicationsExpectant managementPain scoresLabor inductionNonprivate insuranceOperative deliveryCesarean deliveryVaginal deliveryDesign and methods of a translational, community-based, lifestyle weight management pilot intervention trial in breast cancer survivors with overweight or obesity
Haynam M, Chaplow Z, DeScenza V, Bowman J, Dispennette K, Zhang X, Kilar M, Hohn S, Fairman C, Lustberg M, Focht B. Design and methods of a translational, community-based, lifestyle weight management pilot intervention trial in breast cancer survivors with overweight or obesity. Contemporary Clinical Trials Communications 2023, 33: 101154. PMID: 37250507, PMCID: PMC10220259, DOI: 10.1016/j.conctc.2023.101154.Peer-Reviewed Original ResearchBreast cancer survivorsLifestyle weight management interventionsWeight management programWeight management interventionsPilot trialCancer survivorsPreliminary efficacyPilot intervention trialPatient-reported outcomesLifestyle behavior changeSignificant weight gainBreast cancer treatmentMode of deliveryCommunity-based intervention modelMulti-component interventionCommunity-based interventionsQuality of lifeTrial feasibilityDietary modificationCardiometabolic diseasesIntervention trialsCancer recurrenceEfficacy trialsOverweightWeight gainDisruption in Cancer Care During Early Survivorship due to the COVID-19 Pandemic and Patient Satisfaction with Telemedicine
Bellizzi K, Ligus K, Fritzson E, Salafia C, Sanft T, Park C. Disruption in Cancer Care During Early Survivorship due to the COVID-19 Pandemic and Patient Satisfaction with Telemedicine. Supportive Care In Cancer 2023, 31: 291. PMID: 37084094, PMCID: PMC10119514, DOI: 10.1007/s00520-023-07767-7.Peer-Reviewed Original ResearchConceptsCancer care disruptionsCare disruptionsCare appointmentsPatient satisfactionEarly survivorshipVirtual visitsCOVID-19 pandemicSurvivorship care deliveryCancer survivorship careMode of deliverySupportive careSurvivorship carePerson appointmentsElective surgeryVirtual appointmentsColorectal cancerCancer careCancer patientsPerson visitsTelehealth modalitiesMost survivorsPatient questionsCare deliveryREDCap surveySocial work servicesOutcomes among Neonates after a Diagnosis of Persistent or Transient Fetal Growth Restriction Delivered at Term
Ramos S, Has P, Gimovsky A, Danilack V, Savitz D, Lewkowitz A. Outcomes among Neonates after a Diagnosis of Persistent or Transient Fetal Growth Restriction Delivered at Term. American Journal Of Perinatology 2023, 41: e1470-e1477. PMID: 36894159, PMCID: PMC10562520, DOI: 10.1055/a-2051-3859.Peer-Reviewed Original ResearchFetal growth restrictionLater gestational agesNeonatal outcomesGestational ageNeonatal morbidityGrowth restrictionAbnormal umbilical artery Doppler studyExact testNeonatal intensive care unit admissionIntensive care unit admissionUmbilical artery Doppler studiesHigher body mass indexComposite neonatal outcomeCare unit admissionTertiary care centerRespiratory distress syndromeBody mass indexMode of deliveryFisher's exact testComposite morbidityFGR pregnanciesLast ultrasoundUnit admissionApgar scoreDelivery complicationsAssessment of Neurodevelopment in Infants With and Without Exposure to Asymptomatic or Mild Maternal SARS-CoV-2 Infection During Pregnancy
Firestein M, Shuffrey L, Hu Y, Kyle M, Hussain M, Bianco C, Hott V, Hyman S, Kyler M, Rodriguez C, Romero M, Lopez H, Alcántara C, Amso D, Austin J, Bain J, Barbosa J, Battarbee A, Bruno A, Ettinger S, Factor-Litvak P, Gilboa S, Goldman S, Gyamfi-Bannerman C, Maniatis P, Marsh R, Morrill T, Mourad M, Muhle R, Newes-Adeyi G, Noble K, O’Reilly K, Penn A, Reichle L, Sania A, Semenova V, Silver W, Smotrich G, Tita A, Tottenham N, Varner M, Welch M, Zork N, Garey D, Fifer W, Stockwell M, Monk C, Dawood F, Dumitriu D. Assessment of Neurodevelopment in Infants With and Without Exposure to Asymptomatic or Mild Maternal SARS-CoV-2 Infection During Pregnancy. JAMA Network Open 2023, 6: e237396. PMID: 37036706, PMCID: PMC10087058, DOI: 10.1001/jamanetworkopen.2023.7396.Peer-Reviewed Original ResearchConceptsMaternal SARS-CoV-2 infectionSARS-CoV-2 infectionInfant neurodevelopmentPrenatal exposureCohort studyNeurodevelopmental outcomesPregnant individualsMild SARS-CoV-2 infectionAsymptomatic SARS-CoV-2 infectionGross motorFine motorMultisite prospective cohort studySubdomain scoresSARS-CoV-2 exposureProspective cross-sectional studyAssessment of neurodevelopmentProspective cohort studyInfant neurodevelopmental outcomesMean maternal ageInfants of mothersTrimester of exposureInfant gestational ageCross-sectional studyMode of deliveryNon-Hispanic ethnicityOptimal Dose of Spinal Bupivacaine on Maternal and Fetal Outcomes in Parturients Undergoing Combined Technique for Labor Analgesia: A Randomized Double Blinded Prospective Study
Orlando B, Stein D, Donovan J, White J, Bandovic I, Ananthasingam P, Lin H, Marenco J, Saloum M, Mahoney B, Kassapidis D, Epstein J. Optimal Dose of Spinal Bupivacaine on Maternal and Fetal Outcomes in Parturients Undergoing Combined Technique for Labor Analgesia: A Randomized Double Blinded Prospective Study. Journal Of Scientific Innovation In Medicine 2023, 6 DOI: 10.29024/jsim.161.Peer-Reviewed Original ResearchFetal heart rateDose of spinal bupivacaineVisual analog scaleFetal bradycardiaMode of deliveryHypotensive episodesSpinal bupivacaineBlood pressureRandomized double blind prospective studyDouble blind prospective studyCombined spinal-epiduralMaternal blood pressureDoses of vasopressorsBlinded prospective studyMcg of fentanylMinimal side effectsUrban teaching hospitalMaternal hypotensionFetal outcomesLabor analgesiaSpinal-epiduralOptimal analgesiaPain scoresAdequate BPIntrathecal dose
2022
Mode of Delivery in Antepartum Singleton Stillbirths and Associated Risk Factors
Underwood K, Reddy UM, Hosier H, Sweeney L, Campbell KH, Xu X. Mode of Delivery in Antepartum Singleton Stillbirths and Associated Risk Factors. American Journal Of Perinatology 2022, 41: e193-e203. PMID: 35850142, DOI: 10.1055/s-0042-1750795.Peer-Reviewed Original ResearchMode of deliveryAntepartum stillbirthCesarean deliveryPrior cesareanVaginal deliveryMaternal hospital discharge recordsLower likelihoodAssociated risk factorsWeeks of gestationHospital discharge recordsNon-clinical factorsUrban teaching hospitalMultivariable regression analysisPopulation-based sampleFetal death certificatesSingleton stillbirthsPrimary outcomeHospital characteristicsRisk factorsTeaching hospitalDeath certificatesMultivariable regressionCesareanPatientsStillbirthMaternal Outcomes in Subsequent Pregnancies After Classical Cesarean Delivery
Thompson BB, Reddy UM, Burn M, Abdel-Razeq S, Xu X. Maternal Outcomes in Subsequent Pregnancies After Classical Cesarean Delivery. Obstetrics And Gynecology 2022, 140: 212-219. PMID: 35852271, DOI: 10.1097/aog.0000000000004869.Peer-Reviewed Original ResearchConceptsPrior classical cesarean deliveryLow transverse cesarean deliveryPrior low transverse cesarean deliveryClassical cesarean deliverySevere maternal morbidityClinical risk factorsCesarean deliveryUterine ruptureMaternal outcomesSubsequent pregnancyHospital characteristicsRate of SMMPatient clinical risk factorsNational Inpatient Sample databaseLive singleton birthsWeeks of gestationMode of deliveryCross-sectional analysisMaternal morbiditySingleton birthsRisk factorsOutcome measuresMultivariable regressionHigh riskPropensity score methodsEarly infant diagnosis of HIV infection at the John F. Kennedy Medical Center, Monrovia, Liberia
I U U, Adeiza M, Ideh R, Ogbuagu O. Early infant diagnosis of HIV infection at the John F. Kennedy Medical Center, Monrovia, Liberia. HIV Research & Clinical Practice 2022, 23: 136-140. PMID: 35703420, DOI: 10.1080/25787489.2022.2086093.Peer-Reviewed Original ResearchConceptsVertical transmission rateVertical transmissionMTCT programmePCR testingEarly infant diagnosis programHIV DNA PCR testingRetrospective cross-sectional analysisDemographics of mothersDNA PCR testingExpansion of preventionHIV DNA PCRHIV-positive childrenHIV-positive mothersInfectious disease clinicPost-exposure prophylaxisEarly neonatal deathNew HIV infectionsMode of deliveryLogistic regression analysisBinomial logistic regression analysisCross-sectional analysisPMTCT programmeCaesarean sectionExclusive breastfeedingDisease clinicPostpartum Length of Stay and Hospital Readmission Before and During the Coronavirus Disease 2019 (COVID-19) Pandemic
Handley SC, Gallagher K, Lindgren E, Lo JY, Burris HH, Dysart KC, Greenspan J, Culhane JF, Son M. Postpartum Length of Stay and Hospital Readmission Before and During the Coronavirus Disease 2019 (COVID-19) Pandemic. Obstetrics And Gynecology 2022, 139: 381-390. PMID: 35115443, DOI: 10.1097/aog.0000000000004687.Peer-Reviewed Original ResearchConceptsCoronavirus disease 2019 (COVID-19) pandemicObstetric patientsHospital readmissionMode of deliveryPostpartum hospitalizationDisease 2019 pandemicHospitalization dischargeCOVID-19 pandemicRetrospective cohort studyWeeks of gestationDays of deliveryLogistic mixed-effects modelsCohort studyHospitalization lengthSecondary outcomesPrimary outcomeAdjusted analysisStudy cohortVaginal birthCesarean birthReadmissionPostpartum lengthPatientsHospitalizationMixed-effects modelsHypertension in pregnancy and adverse outcomes among low‐risk nulliparous women expectantly managed at or after 39 weeks: a secondary analysis of a randomised controlled trial
Bartal M, Premkumar A, Rice M, Reddy U, Tita ATN, Silver RM, El‐Sayed Y, Wapner R, Rouse DJ, Saade GR, Thorp JM, Costantine M, Chien EK, Casey BM, Srinivas SK, Swamy GK, Simhan HN, Health H. Hypertension in pregnancy and adverse outcomes among low‐risk nulliparous women expectantly managed at or after 39 weeks: a secondary analysis of a randomised controlled trial. BJOG An International Journal Of Obstetrics & Gynaecology 2022, 129: 1396-1403. PMID: 34927787, PMCID: PMC9207156, DOI: 10.1111/1471-0528.17059.Peer-Reviewed Original ResearchConceptsAdverse maternal outcomesLow-risk nulliparous womenHypertensive disordersMaternal outcomesSecondary outcomesNulliparous womenAdverse outcomesComposite adverse maternal outcomeIntensive care unit admissionSecondary analysisCare unit admissionSevere neonatal complicationsWeeks of gestationMode of deliveryNulliparous individualsMaternal compositeNeonatal complicationsPerinatal compositePostpartum infectionUnit admissionCaesarean deliveryExpectant managementPlacental abruptionVenous thromboembolismGestational age
2021
Mode of Delivery, Birth Characteristics and Early-Onset Non-Hodgkin Lymphoma in a Population-Based Case-Control Study
Dwyer KE, Wang R, Cozen W, Cartmel B, Wiemels JL, Morimoto LM, Metayer C, Ma X. Mode of Delivery, Birth Characteristics and Early-Onset Non-Hodgkin Lymphoma in a Population-Based Case-Control Study. Cancer Epidemiology Biomarkers & Prevention 2021, 30: cebp.0535.2021. PMID: 34548330, DOI: 10.1158/1055-9965.epi-21-0535.Peer-Reviewed Original ResearchConceptsNon-Hodgkin lymphomaT-cell non-Hodgkin lymphomaCase-control studyBirth characteristicsMode of deliveryYear of birthOdds ratioNHL riskUnconditional multivariable logistic regression modelsPopulation-based case-control studyCases of NHLMultivariable logistic regression modelConfidence intervalsAge of diagnosisPediatric Burkitt lymphomaLogistic regression modelsCesarean sectionHistologic subtypeDecreased riskHodgkin's lymphomaMaternal ageBurkitt's lymphomaElevated riskLower riskMaternal education
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