2025
Demographic Factors and Burnout Outcomes Associated With Disability Status Uncertainty in U.S. Medical Students.
Pereira-Lima K, Meeks L, Nguyen M, Sheets Z, Jain N, Stergiopoulos E, Addams A, Moreland C, Boatright D. Demographic Factors and Burnout Outcomes Associated With Disability Status Uncertainty in U.S. Medical Students. Academic Medicine 2025 PMID: 40550106, DOI: 10.1097/acm.0000000000006128.Peer-Reviewed Original ResearchMedical studentsDisability statusIncreased risk of burnoutStigma-related concernsRisk of burnoutAssociated with significantly greater oddsLegal definition of disabilitySecond-year medical studentsU.S. medical studentsPromote well-beingMultivariate logistic regressionAuthors analyzed dataBurnout outcomesOldenburg Burnout Inventory for Medical StudentsDefinition of disabilityHigh burnoutMedical traineesGreater oddsDemographic associationsCultural barriersLogistic regressionDemographic characteristicsBurnoutDemographic factorsOddsIntravenous thrombolysis for acute ischemic stroke patients with cerebral amyloid angiopathy
Chen H, Colasurdo M, Khunte M, Malhotra A, Gandhi D. Intravenous thrombolysis for acute ischemic stroke patients with cerebral amyloid angiopathy. Journal Of The Neurological Sciences 2025, 475: 123586. PMID: 40561725, DOI: 10.1016/j.jns.2025.123586.Peer-Reviewed Original ResearchAssociated with significantly higher oddsSignificantly higher oddsHigher oddsMultivariate logistic regressionAcute ischemic stroke patientsIn-hospital mortalityAcute ischemic strokeLogistic regressionAssociated with higher oddsIntravenous thrombolysisDatabase of hospitalizationsAssociated with older agePropensity score matchingSelf-careBalanced treatment groupsIschemic stroke patientsIntracerebral hemorrhageHome dischargeStroke patientsSecondary outcomesCerebral amyloid angiopathyPrimary outcomeOddsScore matchingHemorrhagic cerebrovascular diseaseAge, Race, and Ethnicity of Maternal Grandparents in Autism Spectrum Disorder, a California Multigenerational Study
Chow T, Meng Q, Xiao J, O'Sharkey K, Liew Z, Ritz B. Age, Race, and Ethnicity of Maternal Grandparents in Autism Spectrum Disorder, a California Multigenerational Study. Autism Research 2025 PMID: 40542519, DOI: 10.1002/aur.70074.Peer-Reviewed Original ResearchOdds ratioOlder grandparentsBirth cohort studyMother-child pairsHispanic grandmothersASD riskCohort studyInfluence of ageInverse associationWhite raceInvestigate associationsGrandparent ageYounger ageLogistic regressionOlder ageAutism spectrum disorderSpectrum disorderRace/ethnicityAgeOddsRiskMaternal grandparentsGrandparentsDisordersGrandmothers2092-LB: Association of Fingerstick-Detected Hyperglycemia with Urinary Incontinence in Veterans Affairs Nursing Home Residents—A Case-Crossover Study
LEE A, SHI Y, LIPSKA K, BOSCARDIN J, LEE S. 2092-LB: Association of Fingerstick-Detected Hyperglycemia with Urinary Incontinence in Veterans Affairs Nursing Home Residents—A Case-Crossover Study. Diabetes 2025, 74 DOI: 10.2337/db25-2092-lb.Peer-Reviewed Original ResearchNursing home residentsCase-crossover studyHome residentsNon-Hispanic blacksNon-Hispanic whitesConditional logistic regressionMDS assessmentUrinary incontinenceLogistic regressionUrinary incontinence symptomsStudy inclusionNursesResidentsHigh blood glucose levelsAssessment of urinary incontinenceBlood glucoseIncontinence symptomsCoefficient of variationGlucose measurementsFingerstick measurementsFingerstick glucose measurementsAssociationFingerstick glucoseFrequent urinationBlood glucose levelsLatent Health Status Trajectories in Individuals With New or Worsening Claudication Symptoms.
Grubman S, Romain G, Cleman J, Scierka L, Pajarillo C, Kluger J, Mena-Hurtado C, Smolderen K. Latent Health Status Trajectories in Individuals With New or Worsening Claudication Symptoms. Journal Of The American Heart Association 2025, 14: e039455. PMID: 40530482, DOI: 10.1161/jaha.124.039455.Peer-Reviewed Original ResearchConceptsHealth status trajectoriesPeripheral artery disease careStatus trajectoriesDisease careHealth statusClaudication symptomsTrajectory subgroupsPeripheral Artery QuestionnaireVascular specialty clinicsPeripheral artery questionnaire scoresHierarchical multivariable logistic regressionImprove health statusMultivariate logistic regressionClinically meaningful thresholdsRegistry of patientsPsychosocial factorsBiopsychosocial modelDepressive symptomsSpecialty clinicsAlcohol use disorderQuestionnaire scoresRecovery trajectoriesLogistic regressionHealthLatent trajectory modelsPredictors of Physical, Chiropractic, and Acupuncture Therapy Utilization in the Three Months Following Newly Diagnosed Low Back Pain.
Seddio A, Dhodapkar M, Halperin S, Jabbouri S, Gouzoulis M, Joo P, Grauer J. Predictors of Physical, Chiropractic, and Acupuncture Therapy Utilization in the Three Months Following Newly Diagnosed Low Back Pain. Clinical Spine Surgery A Spine Publication 2025 PMID: 40521727, DOI: 10.1097/bsd.0000000000001859.Peer-Reviewed Original ResearchLow back painChiropractic therapyAcupuncture therapyBack painDays of low back painNonclinical factorsLow back pain patientsPredictors of CT utilizationTherapy utilizationMultivariate logistic regressionMusculoskeletal problemsPhysical therapyElixhauser Comorbidity IndexIndependent predictorsLogistic regressionCT utilizationUtilization patternsAcupunctureLevel IIIMale sexExclusion criteriaComorbidity indexTherapy typeNational levelPainA case-control study of early-life residential exposure to tetrachloroethylene and risks of childhood cancer and birth defects
Rhee J, Michalski A, Kuliszewski M, Musco J, Adler C, Xie S, Friesen M, Insaf T, Purdue M. A case-control study of early-life residential exposure to tetrachloroethylene and risks of childhood cancer and birth defects. Environment International 2025, 201: 109600. PMID: 40516285, DOI: 10.1016/j.envint.2025.109600.Peer-Reviewed Original ResearchConceptsRisk of childhood cancerCase-control studyChildhood cancerNew York CityNew York State Cancer RegistryBureau of Vital StatisticsOdds ratioCases of childhood cancerState Cancer RegistryNon-whiteConfidence intervalsUnconditional logistic regressionComputed odds ratiosBirth Defects RegistryBirth defectsCancer RegistryExposure-response effectTetrachloroethylene exposureBirth certificatesVital statisticsResidential exposureInvestigate associationsCollege-educatedLogistic regressionStrong associationsStill we rise: research on bias and discrimination will endure
Gonsalves G. Still we rise: research on bias and discrimination will endure. International Journal For Equity In Health 2025, 24: 167. PMID: 40495157, PMCID: PMC12153171, DOI: 10.1186/s12939-025-02537-9.Peer-Reviewed Original ResearchConceptsMeasures of implicitCommunity health centersVaping behaviorUS National Institutes of HealthNational Institutes of HealthExplicit measuresMeta-regression approachCurrent smokingHealth centersInstitutes of HealthAssess smokingCurrent US administrationConduct of researchUS National InstitutesDonald J. TrumpPresident Donald J. TrumpLogistic regressionResearch fundersCenter membersUS administrationDominant groupPolitical interferenceTrump administrationIdeological reasonsComparing targetsThe incidence and trends of diving-related spine injuries in the United States and risk factors associated with spinal cord injury
Seddio A, Jabbouri S, Vasudevan R, Gouzoulis M, Day W, Maloy G, Varthi A, Rubio D, Grauer J. The incidence and trends of diving-related spine injuries in the United States and risk factors associated with spinal cord injury. Spinal Cord 2025, 1-7. PMID: 40490487, DOI: 10.1038/s41393-025-01098-6.Peer-Reviewed Original ResearchEstimated annual percentage changeSpine injuriesSpinal cord injuryRisk factorsLumbar spineInjury prevention programsAnnual percentage changePublic health initiativesCord injuryCervical spine surgeryMultivariate logistic regressionLog-linear regressionUnique risk factorsHealth initiativesUnited StatesCervical spondylolisthesisElixhauser Comorbidity IndexCervical spinePrevention programsAdministrative datasetsLogistic regressionSpine surgeryPercentage changeCervical stenosisOlder ageCervical radiculopathy management with physical, chiropractic, and acupuncture therapy: Factors associated with different therapy utilization patterns
Seddio A, Katsnelson B, Gouzoulis M, Jabbouri S, Jonnalagadda A, Day W, Rubio D, Grauer J. Cervical radiculopathy management with physical, chiropractic, and acupuncture therapy: Factors associated with different therapy utilization patterns. North American Spine Society Journal (NASSJ) 2025, 22: 100610. DOI: 10.1016/j.xnsj.2025.100610.Peer-Reviewed Original ResearchAcupuncture therapyChiropractic therapyPhysical therapyCervical radiculopathyPredictors of CT utilizationUtilization patternsCervical spine pathologyFirst-time diagnosisLow comorbidity burdenMultivariate logistic regressionCare pathwaysDiagnose CRElixhauser Comorbidity IndexAT sessionsNonclinical predictorsSpine pathologyPotential inequalitiesLogistic regressionComorbidity burdenCT utilizationAcupunctureCR patientsMale sexDiagnosis of CRExclusion criteriaPrevalence, Awareness, and Factors Associated with Hypertension Among Adults in Rural Southwestern Uganda: A Baseline Survey
Kansiime G, Nuwagira E, Obwoya P, Baluku J, Kanyesigye M, Twesiime C, Ssebutinde P, Muhindo R, Muyingo A, Kananura K, Tusingwire P, Atukunda E, Kalyesubula R, Bajunirwe F, Muiru A. Prevalence, Awareness, and Factors Associated with Hypertension Among Adults in Rural Southwestern Uganda: A Baseline Survey. International Journal Of General Medicine 2025, 18: 3289-3300. PMID: 40575767, PMCID: PMC12199733, DOI: 10.2147/ijgm.s522911.Peer-Reviewed Original ResearchFactors associated with hypertensionRural southwestern UgandaSouthwestern UgandaBaseline surveyWHO STEPS questionnaireServings of fruitsCommunity health workersPhysically active populationFactors of hypertensionBlood pressureRisk factorsRural sub-Saharan AfricaSTEPS questionnaireLifestyle behaviorsPhysical activityHealth workersHypertension prevalenceTargeted interventionsMbarara districtResearch assistantsPreventable deathsAntihypertensive useLogistic regressionSub-Saharan AfricaRural communitiesTrends in Tdap and influenza vaccination in pregnancy relative to the coronavirus disease-19 pandemic
Dave E, Culhane J, Lundsberg L, Partridge C, Kohari K, Denoble A. Trends in Tdap and influenza vaccination in pregnancy relative to the coronavirus disease-19 pandemic. Vaccine 2025, 61: 127329. PMID: 40449181, DOI: 10.1016/j.vaccine.2025.127329.Peer-Reviewed Original ResearchAcute COVIDDiagnosis of chronic hypertensionInfluenza vaccine administrationEstimated due dateLogistic regression analysisVaccination ratesPregnant patientsGestational ageInfluenza vaccineChronic hypertensionRetrospective reviewTdap vaccinationMaternal ageCOVID periodPatient characteristicsTdapPre-COVIDVaccine administrationInfluenzaMultinomial logistic regression analysisCombat vaccine hesitancyPatientsVaccination statusCoronavirus disease-19 pandemicLogistic regressionNationwide sociodemographic patterns in airborne exposure to probable carcinogens from industrial sources
Pruitt C, Fisher J, Flory A, Graubard B, Ward M, Jones R, Madrigal J. Nationwide sociodemographic patterns in airborne exposure to probable carcinogens from industrial sources. The Science Of The Total Environment 2025, 986: 179674. PMID: 40449360, DOI: 10.1016/j.scitotenv.2025.179674.Peer-Reviewed Original ResearchConceptsWhite populationLow socioeconomic statusCensus tract boundariesHigh school educationInternational Agency for Research on CancerSociodemographic characteristicsSociodemographic groupsSociodemographic predictorsSocioeconomic statusSociodemographic patternsCensus tractsProbable carcinogensLogistic regressionOddsIndustrial air emissionsSchool educationLatinosBlack AmericansTract boundariesEvaluate differencesHealth-Related Quality of Life Metrics in Patients With Retrograde Cricopharyngeus Dysfunction.
Jacobs D, Duffy J, Lerner B, Lerner M. Health-Related Quality of Life Metrics in Patients With Retrograde Cricopharyngeus Dysfunction. Annals Of Otology Rhinology & Laryngology 2025, 34894251342088. PMID: 40420548, DOI: 10.1177/00034894251342088.Peer-Reviewed Original ResearchPROMIS-29 questionnaireRetrograde cricopharyngeus dysfunctionPROMIS-29Quality of lifeLevels of anxietySubdomains of quality of lifeHealth-related quality of life metricsHealth-related qualitySocial Anxiety QuestionnaireAnxiety metricsQuality of life metricsPain impairmentReport anxietyMonitoring response to therapyLogistic regressionAnxiety QuestionnaireNational averageResponse to therapyMonitoring therapy responseQuestionnaireClinical questionsSocial anxietyAnxietySleep impairmentCliniciansDifferences in In-Hospital and Post-Discharge Ischemic Stroke Care According to Prestroke Functional Status.
Wechsler P, Mistry E, Sucharew H, Robinson D, Stanton R, de Los Rios La Rosa F, Mackey J, Ferioli S, Demel S, Coleman E, Jasne A, Slavin S, Walsh K, Star M, Haverbusch M, Alwell K, Woo D, Kleindorfer D, Kissela B. Differences in In-Hospital and Post-Discharge Ischemic Stroke Care According to Prestroke Functional Status. Journal Of The American Heart Association 2025, 14: e040499. PMID: 40417811, DOI: 10.1161/jaha.124.040499.Peer-Reviewed Original ResearchConceptsIschemic stroke carePrestroke disabilityStroke careIn-hospitalGreater Cincinnati/Northern Kentucky populationAssociated with lower oddsPopulation-based dataSecondary stroke prevention treatmentPrestroke functional statusMedical decision-makingCare continuumStroke prevention treatmentRehabilitation therapyLower oddsIschemic stroke patientsFunctional statusStroke reperfusion therapyStroke patientsLogistic regressionCareDisabilityKentucky populationAcute ischemic strokeReperfusion therapyPrestrokeAcoustic-based machine learning approaches for depression detection in Chinese university students
Wei Y, Qin S, Liu F, Liu R, Zhou Y, Chen Y, Xiong X, Zheng W, Ji G, Meng Y, Wang F, Zhang R. Acoustic-based machine learning approaches for depression detection in Chinese university students. Frontiers In Public Health 2025, 13: 1561332. PMID: 40443925, PMCID: PMC12119278, DOI: 10.3389/fpubh.2025.1561332.Peer-Reviewed Original ResearchConceptsPatient Health Questionnaire-9Mel-frequency cepstral coefficientsLinear discriminant analysisMachine learning algorithmsAcoustic featuresLearning algorithmsIdentification of depressionMonitoring of depressionCross-sectional studyGlobal public health problemSHapley Additive exPlanationsDepression screeningSelf-report methodsPublic health problemIdentifying depressionLinear discriminant analysis modelDepression assessmentSupport vector classificationAutomated identificationMachine learning approachArea under the curveHealth problemsOpenSMILE toolkitLogistic regressionCepstral coefficientsSpinal cord stimulator utilization trends and predictors of unsuccessful trial-to-implant conversion
Day W, Maloy G, Winter A, Chapman K, Seddio A, Doshi R, Ratnasamy P, Varthi A, Fourman M, Grauer J. Spinal cord stimulator utilization trends and predictors of unsuccessful trial-to-implant conversion. North American Spine Society Journal (NASSJ) 2025, 22: 100616. PMID: 40548099, PMCID: PMC12182330, DOI: 10.1016/j.xnsj.2025.100616.Peer-Reviewed Original ResearchSpinal cord stimulationSpinal cord stimulator trialFactors associated with failureUtilization of spinal cord stimulationSpinal cord stimulator implantationPermanent SCS implantationLower oddsMultivariate logistic regressionAssociated with lower oddsLow comorbidity burdenSCS trialSCS implantationCord stimulationNeurological painMale sexPermanent implantationAnnual incidenceComorbidity burdenClaims databaseTobacco useLogistic regressionNeuromodulatory devicesOlder ageImplantationUtilization trendsHuman Immunodeficiency Virus Infection and Long COVID: A RECOVER Program, Electronic Health Record–Based Cohort Study
Hawkins K, Dandachi D, Verzani Z, Brannock M, Lewis C, Abedian S, Jaferian S, Wuller S, Truong J, Witvliet M, Dymond G, Mehta H, Patel P, Hill E, Weiner M, Carton T, Kaushal R, Feuerriegel E, Tran H, Marks K, Oliveira C, Gardner E, Ofotokun I, Gulick R, Erlandson K. Human Immunodeficiency Virus Infection and Long COVID: A RECOVER Program, Electronic Health Record–Based Cohort Study. Clinical Infectious Diseases 2025, ciaf242. PMID: 40354184, DOI: 10.1093/cid/ciaf242.Peer-Reviewed Original ResearchDefinition of Long COVIDICD-10Baseline chronic conditionsLong COVIDElectronic health record databaseIncreased riskHealth record databaseICD-10 codesICD-10 definitionRisk of long COVIDClinical Research NetworkChronic conditionsAcute SARS-CoV-2 infectionHIV statusAnalytic sampleOdds ratioCohort definitionsCohort CollaborationComputable phenotypePhenotype definitionRecord databaseSARS-CoV-2 infectionLogistic regressionResearch NetworkMulticenter studyUnited States racial/ethnic disparities in PGT-A use: an analysis of 2014–2020 SART CORS database
Mason-Otey A, Seifer D. United States racial/ethnic disparities in PGT-A use: an analysis of 2014–2020 SART CORS database. Reproductive Biology And Endocrinology 2025, 23: 66. PMID: 40349066, PMCID: PMC12065204, DOI: 10.1186/s12958-025-01399-8.Peer-Reviewed Original ResearchConceptsPGT-AMultiple logistic regressionART cyclesHispanic womenAsian womenSociety for Assisted Reproductive Technology Clinic Outcome Reporting SystemWhite womenSelection of euploid embryosPreimplantation genetic testingRetrospective cohort studyOutcome Reporting SystemAutologous ART cyclesSART CORS databaseEuploid embryosSART CORSAutologous cyclesCohort studyGenetic testingMinority womenLogistic regressionWomenBackgroundThe useResultsThis studyUnited StatesRacial/ethnic disparitiesExploring the link between grandmaternal air pollution exposure and Grandchild’s ASD risk: A multigenerational population-based study in California
O'Sharkey K, Chow T, Mitra S, Thompson L, Su J, Cockburn M, Liew Z, Ritz B. Exploring the link between grandmaternal air pollution exposure and Grandchild’s ASD risk: A multigenerational population-based study in California. Environment International 2025, 200: 109526. PMID: 40378475, DOI: 10.1016/j.envint.2025.109526.Peer-Reviewed Original ResearchConceptsAir pollutionLand-use regression modelsExposure to air pollutionAP exposureAir pollution exposureMaternal pregnancy exposuresPopulation-based cohortPopulation-based studyMultigenerational exposurePollution exposureLand-useIncreased ASD riskPregnancy exposurePollutionASD riskInfluence ASD riskMaternal pregnancyExposure levelsInfant exposureLogistic regressionMaternal exposureRisk factorsRegression modelsIncreased prevalenceEnvironmental factors
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