2025
Biosocial Variation in Treatment Response to GLP-1s: Implications for Clinical Care and Health Policy
Horwitz R, Otaka S, Conroy A, Cullen M, Matory A, Singer B, Sim I. Biosocial Variation in Treatment Response to GLP-1s: Implications for Clinical Care and Health Policy. The American Journal Of Medicine 2025 PMID: 40393609, DOI: 10.1016/j.amjmed.2025.05.016.Peer-Reviewed Original ResearchTreatment-resistant obesityTrajectory of obesityResponse to treatmentObesity-related disordersRandomized controlled trialsReal-world evidence studiesTreatment responseClinical managementEvidence studiesGLP-1sControlled trialsPatientsObesityWeight lossBody weightPathogenesisAverage treatment responseHealth policyTreatmentPhysiological systemsGovernance for anti-racist AI in healthcare: integrating racism-related stress in psychiatric algorithms for Black Americans
Fields C, Black C, Thind J, Jegede O, Aksen D, Rosenblatt M, Assari S, Bellamy C, Anderson E, Holmes A, Scheinost D. Governance for anti-racist AI in healthcare: integrating racism-related stress in psychiatric algorithms for Black Americans. Frontiers In Digital Health 2025, 7: 1492736. PMID: 40444183, PMCID: PMC12119476, DOI: 10.3389/fdgth.2025.1492736.Peer-Reviewed Original ResearchRacism-related stressBlack patientsBlack AmericansClinical algorithmAnti-Black racismHealthcare interventionsAnti-Black biasHealth outcomesHealth policySocioeconomic statusIntervention modelHistory of enslavementPatient outcomesCommunity membersHealthcareGenerational traumaHealthAmerica's historyBlack researchersSources of varianceClinical practiceEquitable outcomesSocial factorsRacial groupsAI governanceIntegrating public preferences to overcome racial disparities in research: findings from a US survey on enhancing trust in research data-sharing practices
de Rivera S, Zhao Y, Omollo S, Eslami S, Benda N, Sharma Y, Turchioe M, Sharko M, Dugdale L, Creber R. Integrating public preferences to overcome racial disparities in research: findings from a US survey on enhancing trust in research data-sharing practices. JAMIA Open 2025, 8: ooaf031. PMID: 40322632, PMCID: PMC12047078, DOI: 10.1093/jamiaopen/ooaf031.Peer-Reviewed Original ResearchPublic health organizationsRacial disparitiesAssess sociodemographic differencesHealth OrganizationEthnic minority participantsPersonal research dataLogistic regression modelsPotential unintended consequencesHealth policyUS adultsSociodemographic differencesMental healthPatient's viewpointHealth dataBlack participantsWhite participantsParticipants' concernsParticipants' perspectivesEvaluated participants' preferencesParticipants' preferencesMinority participantsLow participationUS surveyRisk of distrustEnhance trustAfrican Youth in Mind – Protocol of a Pilot feasibility trial of a brief psychological Intervention for older adolescents with depression delivered through senior high schools in Navrongo, Ghana
Jopling R, Attah D, Abas M, Adde K, Goldsmith K, Bere T, Nyamayaro P, Aborigo R, Barrett B, Owusu L, Glozah F, Akanlu A, Bawa S, Achana F, Danese A, Smith P, Seward N, Kumwenda M, Chibanda D, Weobong B. African Youth in Mind – Protocol of a Pilot feasibility trial of a brief psychological Intervention for older adolescents with depression delivered through senior high schools in Navrongo, Ghana. PLOS ONE 2025, 20: e0319462. PMID: 40168302, PMCID: PMC11960926, DOI: 10.1371/journal.pone.0319462.Peer-Reviewed Original ResearchConceptsPatient Health Questionnaire-9Enhanced usual careIntegration of mental health servicesPsychological interventionsRandomised controlled pilot trialMonths post baseline assessmentPilot trialPrimary healthcare systemMental health componentMental health servicesEvidence-based interventionsControlled pilot trialProblem-solving therapySymptoms of depressionAdolescent health policyPilot feasibility trialUsual careHealth servicesSchool-going youthFormative researchCost-effectiveness evaluationFeasibility trialHealth policyPost-baseline assessmentHealth componentEffect of a needs-based model of care on the characteristics of healthcare services in England: the i-THRIVE National Implementation Programme
Sippy R, Efstathopoulou L, Simes E, Davis M, Howell S, Morris B, Owrid O, Stoll N, Fonagy P, Moore A. Effect of a needs-based model of care on the characteristics of healthcare services in England: the i-THRIVE National Implementation Programme. Epidemiology And Psychiatric Sciences 2025, 34: e21. PMID: 40135635, PMCID: PMC11955426, DOI: 10.1017/s2045796025000101.Peer-Reviewed Original ResearchConceptsWorking relationshipsImplementation programmeComparison sitesModels of careSite staffNational implementation programmeDifference-in-differences modelDifference-in-difference-in-differencesExperiences of staffDifference-in-difference-in-differences modelInfluence programme successQuasi-experimental designTHRIVE FrameworkStaff surveyPolicy goalsEffective working relationshipsSite-level characteristicsFidelity scoresHealth policyHealth systemHealthcare servicesNeeds-based modelYoung peopleProgramme successStaffNovel indices of state- and county-level social disadvantage in older Americans and disparities in mortality
Wang Y, Zang E, Davis-Plourde K, Gill T, Becher R. Novel indices of state- and county-level social disadvantage in older Americans and disparities in mortality. Health & Place 2025, 92: 103438. PMID: 40058245, PMCID: PMC12142587, DOI: 10.1016/j.healthplace.2025.103438.Peer-Reviewed Original ResearchConceptsIncreased mortality riskContextual disadvantageOlder personsOlder AmericansCommunity-living older personsSocial disadvantageMortality riskIndices of social disadvantageReduce health disparitiesPopulation of older AmericansCounty-levelPublic health policiesNon-disadvantaged groupsMortality disparitiesHealth disparitiesHealth policyMortality existUnited StatesDisadvantaged countiesNegative binomial modelGeriatric populationComposite indexDisparitiesDisadvantaged statesMultidimensional factorsVoting Trends Among Otolaryngology–Head and Neck Surgery Trainees
Bourdillon A, Moneer O, Zhan K, Lee J, Valenzuela C, Farzal Z. Voting Trends Among Otolaryngology–Head and Neck Surgery Trainees. Laryngoscope Investigative Otolaryngology 2025, 10: e70103. PMID: 39990818, PMCID: PMC11845977, DOI: 10.1002/lio2.70103.Peer-Reviewed Original ResearchElectoral participationVoting participationVoting practicesOtolaryngology-Head and Neck SurgeryPerceived lack of impactClinical dutiesAnalyzed survey dataVoter participationEarly votingVoting trendsElection dayOverall voteCivic engagementVotingElectionProportion of traineesSurvey dataHealth policyLack of impactEligible traineesMitigate barriersNational averageAssess statistical differencesMedical specialtiesPerceived lackHeterogeneous associations between short-term ambient ozone exposure and morbidities from infants to seniors: A nationwide case-crossover study in South Korea
Ahn S, Kang C, Oh J, Yun H, Ahn S, Kim A, Kwon D, Park J, Jang H, Kim E, Bell M, Kim H, Lee W. Heterogeneous associations between short-term ambient ozone exposure and morbidities from infants to seniors: A nationwide case-crossover study in South Korea. Journal Of Hazardous Materials Advances 2025, 17: 100531. DOI: 10.1016/j.hazadv.2024.100531.Peer-Reviewed Original ResearchED admissionMental disordersWarm-season ozoneTargeted public health policiesCase-crossover designNational Health Insurance databaseCase-crossover studyMiddle-aged populationPublic health policiesIndividuals aged 0Health Insurance DatabaseED admission dataHealth policyExcess riskRespiratory diseaseAmbient ozoneAmbient ozone exposureShort-term ozoneEmergency departmentAdmission dataAdmission costsInsurance DatabaseAged 0Heterogeneous associationsAdult age
2024
Impact of strategic public health interventions to reduce tuberculosis incidence in Brazil: a Bayesian structural time-series scenario analysis
Villalva-Serra K, Barreto-Duarte B, Rodrigues M, Queiroz A, Martinez L, Croda J, Rolla V, Kritski A, Cordeiro-Santos M, Sterling T, Araújo-Pereira M, Andrade B. Impact of strategic public health interventions to reduce tuberculosis incidence in Brazil: a Bayesian structural time-series scenario analysis. The Lancet Regional Health - Americas 2024, 41: 100963. PMID: 39759249, PMCID: PMC11697790, DOI: 10.1016/j.lana.2024.100963.Peer-Reviewed Original ResearchPredictors of TB incidencePublic health interventionsReduce TB incidenceTB incidenceVulnerable populationsTB-HIV coinfectionHealth interventionsTB casesTB-diabetesWHO targetTB-HIVCompletion ratesStrategizing public health interventionsTB surveillance dataReducing tuberculosis incidenceNational reporting systemHealth policyDOTS implementationTuberculosis incidenceSurveillance dataPublic health threatContact investigationPreventive therapyInterventionAbsolute reductionResearch utilization competency development in the health workforce pipeline: Design and formative evaluation of learning objectives for health professions students
Yini Karway O, Wleh J, Kpatakolee Y, Sieka J, Candy N, Talbert-Slagle K, Dahn B, Harmon-Gray W, Skrip L. Research utilization competency development in the health workforce pipeline: Design and formative evaluation of learning objectives for health professions students. Health Research Policy And Systems 2024, 22: 158. PMID: 39623382, PMCID: PMC11610060, DOI: 10.1186/s12961-024-01238-z.Peer-Reviewed Original ResearchConceptsHealth professions schoolsResearch utilizationWorkforce pipelineApplication of research evidenceHealth sectorResearch evidenceSchool of Public HealthMiddle-income country contextsGroup discussionsMethodsFocus group discussionsHealth professions studentsCollege of Health SciencesFocus group participantsFormative evaluationFocus group discussionsLife-saving interventionsProfessions studentsHealth policyGroup participantsTime commitmentHealthHealth SciencesPublic healthPharmacy schoolsCompetency areasBiases in COVID-19 vaccine effectiveness studies using cohort design
Agampodi S, Tadesse B, Sahastrabuddhe S, Excler J, Kim J. Biases in COVID-19 vaccine effectiveness studies using cohort design. Frontiers In Medicine 2024, 11: 1474045. PMID: 39540039, PMCID: PMC11557388, DOI: 10.3389/fmed.2024.1474045.Peer-Reviewed Original ResearchCohort designHealth-promoting behaviorsObservational studyPublic health strategiesPublic health policiesMiddle-income countriesPre-existing data sourcesHealthy user biasHealthy vaccinee effectSociodemographic disparitiesHealth strategiesHealth policyOutcome misclassificationSustaining public trustMisclassification biasHealth statusHealthcare systemVaccinee effectSusceptibility biasDiverse populationsCOVID-19Vaccine effectiveness studiesFrailty biasVaccine effectivenessCOVID-19 pandemicThe American Cancer Society National Lung Cancer Roundtable strategic plan: Promoting guideline‐concordant lung cancer staging
Farjah F, Barta J, Wood D, Rivera M, Osarogiagbon R, Smith R, Mullett T, Rosenthal L, Henderson L, Detterbeck F, Silvestri G. The American Cancer Society National Lung Cancer Roundtable strategic plan: Promoting guideline‐concordant lung cancer staging. Cancer 2024, 130: 4167-4176. PMID: 39347610, PMCID: PMC11585343, DOI: 10.1002/cncr.34627.Peer-Reviewed Original ResearchLung cancer stagingCancer stageGuideline recommendationsPerformance feedback mechanismsLung cancerPatient self-advocacyImproving lung cancer stagingCurrent health policyPractice guideline recommendationsCancer treatmentProfessional societiesStage lung cancerLung cancer survivalStage-appropriate therapyLevel of evidenceComparative-effectiveness studiesHealth policyHealth systemCancer survivalLow-to-moderateAccurate stagingRecommended 4Practice guidelinesSelf-advocacyMultidisciplinary expertsCaregivers of children with asthma alarmed by climate change: a cross‐sectional study
Godse S, Shabanova V, Ragavan M, Mitchell M, Chen L, Flom J, Sheares B. Caregivers of children with asthma alarmed by climate change: a cross‐sectional study. Pediatric Pulmonology 2024, 59: 3677-3685. PMID: 39323113, DOI: 10.1002/ppul.27288.Peer-Reviewed Original ResearchCaregivers of childrenCross-sectional studyClimate change-related health risksHealth impacts of climate changeInforming public health policyPublic health policiesReports adverse impactsRespiratory health impactsCaregiver perspectivesCaregiver perceptionsChild's asthmaHealth policyChild healthChild's doctorHealth harmsHealth risksCaregiversWorsening asthma controlAsthma controlAir pollutionAdverse health effectsPulmonology clinicSurvey instrumentUS settingHealth effectsEditorial Commentary: An Anchor-Based Approach Is the Superior, Direct Method for Determining Achievement of Minimal Clinically Important Difference, Substantial Clinical Benefit, and Patient Acceptable Symptom State
Moran J, Jimenez A. Editorial Commentary: An Anchor-Based Approach Is the Superior, Direct Method for Determining Achievement of Minimal Clinically Important Difference, Substantial Clinical Benefit, and Patient Acceptable Symptom State. Arthroscopy The Journal Of Arthroscopic And Related Surgery 2024, 41: 2114-2116. PMID: 39326566, DOI: 10.1016/j.arthro.2024.09.033.Peer-Reviewed Original ResearchPatient-reported outcome measuresMinimal clinically important differencePatient acceptable symptom stateAnchor-based approachClinically important differenceAcceptable symptom stateImportant differenceSymptom statePatient acceptable symptom state thresholdSubstantial clinical benefitInternational Hip Outcome ToolDistribution-based methodsHip Outcome Score-Sports Specific SubscaleHip Outcome ToolClinical benefitAchievement of minimal clinically important differenceClinically meaningful improvementsHip Outcome Score-Activities of Daily LivingClinically meaningful differencesHip Outcome Score-ActivitiesClinical decision-makingDaily livingHealth policyModified Harris Hip ScoreOutcome toolsModeling approaches to inform travel-related policies for COVID-19 containment: A scoping review and future directions
Koiso S, Gulbas E, Dike L, Mulroy N, Ciaranello A, Freedberg K, Jalali M, Walker A, Ryan E, LaRocque R, Hyle E. Modeling approaches to inform travel-related policies for COVID-19 containment: A scoping review and future directions. Travel Medicine And Infectious Disease 2024, 62: 102730. PMID: 38830442, PMCID: PMC11606784, DOI: 10.1016/j.tmaid.2024.102730.Peer-Reviewed Original ResearchPostura de la Sociedad Latinoamericana de Nutrición sobre la participación de actores comerciales y conflictos de intereses
Barquera S, Domínguez-Barreto A, Valero-Morales I, Arellano-Rodríguez M, Cediel G, Ríos-Castillo I, Turnes C, Graciano A, García-Chávez C, Navarro-Rosenblatt D, Pérez-Escamilla R, Ramírez-Zea M, Mialon M, Barnoya J, Bortoletto-Martins A, Abril-Ulloa V, Ochoa-Avilés A, Rivera-Dommarco J, Freire W. Postura de la Sociedad Latinoamericana de Nutrición sobre la participación de actores comerciales y conflictos de intereses. Salud Pública De México 2024, 66: 307-312. PMID: 39977062, DOI: 10.21149/15382.Peer-Reviewed Original ResearchPromote healthy food environmentsHealthy food environmentsFood environmentHealth policyNutrition SocietyNutrition researchImplementation of actionsHealthNutritionContext of relationshipsAcademy membersCommercial entitiesSLANBeverage productsMembersConflict of interestsGuidelinesEducationBeveragesPolicyInterventions to promote readiness for advance care planning: A systematic review and meta-analysis
Tan M, Tang S, Feder S, Xiao J, Huang C, Cook A, Johnson C, Ding J. Interventions to promote readiness for advance care planning: A systematic review and meta-analysis. International Journal Of Nursing Studies 2024, 156: 104778. PMID: 38761437, DOI: 10.1016/j.ijnurstu.2024.104778.Peer-Reviewed Original ResearchAdvance care planningAdvance care planning interventionCare planning interventionCare planningStatistically significant effect of interventionMeta-analysisJoanna Briggs Institute critical appraisal toolsPlanning interventionsBackground Advance care planningSignificant effect of interventionMeta-analysesStages of behavior changeFuture health policyCritical appraisal toolsStandard medical servicesEffectiveness of interventionsPooled effect sizeRandomized controlled trialsMeta-analysis of randomized controlled trialsAppraisal ToolIntervention designHealth policyMedical servicesPromote readinessSystematic reviewQuasi-experimental methods for pharmacoepidemiology: difference-in-differences and synthetic control methods with case studies for vaccine evaluation
Kennedy-Shaffer L. Quasi-experimental methods for pharmacoepidemiology: difference-in-differences and synthetic control methods with case studies for vaccine evaluation. American Journal Of Epidemiology 2024, 193: 1050-1058. PMID: 38456774, PMCID: PMC11228849, DOI: 10.1093/aje/kwae019.Peer-Reviewed Original ResearchConceptsSynthetic control methodDifference-in-differencesHealth policyCase studyAverage treatment effectQuasi-experimental methodPolicyQuasi-experimental designWeight assumptionPopulation-level effectsTime trendsStudy designSources of evidenceConfounding factorsEvaluation studiesPharmacoepidemiologyTarget estimandAbsence of contaminationBurden of Ischemic and Hemorrhagic Stroke Across the US From 1990 to 2019
Renedo D, Acosta J, Leasure A, Sharma R, Krumholz H, de Havenon A, Alahdab F, Aravkin A, Aryan Z, Bärnighausen T, Basu S, Burkart K, Coberly K, Criqui M, Dai X, Desai R, Dharmaratne S, Doshi R, Elgendy I, Feigin V, Filip I, Gad M, Ghozy S, Hafezi-Nejad N, Kalani R, Karaye I, Kisa A, Krishnamoorthy V, Lo W, Mestrovic T, Miller T, Misganaw A, Mokdad A, Murray C, Natto Z, Radfar A, Ram P, Roth G, Seylani A, Shah N, Sharma P, Sheikh A, Singh J, Song S, Sotoudeh H, Vervoort D, Wang C, Xiao H, Xu S, Zand R, Falcone G, Sheth K. Burden of Ischemic and Hemorrhagic Stroke Across the US From 1990 to 2019. JAMA Neurology 2024, 81: 394-404. PMID: 38436973, PMCID: PMC10913004, DOI: 10.1001/jamaneurol.2024.0190.Peer-Reviewed Original ResearchBurden of strokeHemorrhagic strokeBurden trendsGlobal burdenGlobal Burden of Disease StudyBurden of Disease StudyAge-standardized ratesAge-standardized estimatesPublic health policiesStroke-related outcomesIschemic strokeCross-sectional studyPublic health challengeCross-sectional analysisStroke mortalityStroke burdenHealth policyOlder adultsMain OutcomesStroke incidenceStroke casesIntracerebral hemorrhageEscalating burdenHealth challengesSignificant disparitiesOzone-related acute excess mortality projected to increase in the absence of climate and air quality controls consistent with the Paris Agreement
Domingo N, Fiore A, Lamarque J, Kinney P, Jiang L, Gasparrini A, Breitner S, Lavigne E, Madureira J, Masselot P, das Neves Pereira da Silva S, Sheng Ng C, Kyselý J, Guo Y, Tong S, Kan H, Urban A, Orru H, Maasikmets M, Pascal M, Katsouyanni K, Samoli E, Scortichini M, Stafoggia M, Hashizume M, Alahmad B, Diaz M, la Cruz Valencia C, Scovronick N, Garland R, Kim H, Lee W, Tobias A, Íñiguez C, Forsberg B, Åström C, Ragettli M, Guo Y, Pan S, Colistro V, Bell M, Zanobetti A, Schwartz J, Schneider A, Vicedo-Cabrera A, Chen K. Ozone-related acute excess mortality projected to increase in the absence of climate and air quality controls consistent with the Paris Agreement. One Earth 2024, 7: 325-335. PMID: 38420618, PMCID: PMC7615682, DOI: 10.1016/j.oneear.2024.01.001.Peer-Reviewed Original ResearchClimate scenariosOzone-related deathsAir quality regulationsGround-level ozoneAcute mortalityAir quality controlCMIP6 multi-model ensembleParis Climate AgreementMulti-model ensembleQuality regulationsHealth policyEmission changesAssociated with increased mortalityExcess mortalityCMIP6 simulationsClimateParis AgreementEpidemiological dataClimate AgreementDiverse geographical areasCMIP6MortalityGeographical areas
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