2025
Association between in utero exposure to organochlorine pesticides and steroids in cord blood
Chen H, Zhang H, Zheng T, Xia W, Xu S, Chen T, Li Y. Association between in utero exposure to organochlorine pesticides and steroids in cord blood. Environmental Pollution 2025, 382: 126727. PMID: 40578747, DOI: 10.1016/j.envpol.2025.126727.Peer-Reviewed Original ResearchOrganochlorine pesticide exposureOrganochlorine pesticidesRestricted cubic splinesOCP exposureCord bloodUtero exposure to organochlorine pesticidesExposure to organochlorine pesticidesConcentrations of dichlorodiphenyltrichloroethaneSteroid levelsAssociated with hormone levelsCord serum concentrationsLevels of newbornsMother-infant pairsDose-response relationshipCesarean sectionCross-sectional studyEndocrine disruptorsMale infantDose-dependentlyHormone levelsHexachlorocyclohexaneDichlorodiphenyltrichloroethaneSteroidsSteroid concentrationsCordAmino acid patterns predict white matter integrity measures in the brain in patients across the Alzheimer’s disease continuum
Goharmanesh F, Masmoie M, Nasiri H, Sadat-Madani S, Namin S, Damizadeh M, Shakeri S, Sodeifian F, Rajabpour-Sanati A, Bahrainian B, Mohammadi Y, Shushtari A, Mayeli M. Amino acid patterns predict white matter integrity measures in the brain in patients across the Alzheimer’s disease continuum. Metabolic Brain Disease 2025, 40: 227. PMID: 40531346, DOI: 10.1007/s11011-025-01647-1.Peer-Reviewed Original ResearchConceptsWhite matter integrityMean diffusivityDiffusion tensor imagingFractional anisotropyAlzheimer's Disease Neuroimaging InitiativeAxial diffusivityAA metabolic pathwaysReduced white matter integrityDisease continuumDTI-derived metricsWhite matter integrity measuresWhite matter microstructural integrityAD patientsCross-sectional studyUltra-high performance liquid chromatographyPotential therapeutic targetRadial diffusivityDecreased FAIncreased MDStudy groupEarly diagnosisProgression markersAlzheimer's disease continuumAmino acidsMild cognitive impairmentPatient Satisfaction in the Headache Care at the Veterans Health Administration Headache Centers of Excellence: A Cross-Sectional Study
Kimber A, Fenton B, Zhou B, Anthony S, Sico J, Seng E. Patient Satisfaction in the Headache Care at the Veterans Health Administration Headache Centers of Excellence: A Cross-Sectional Study. Journal Of Patient Experience 2025, 12: 23743735251346615. PMID: 40520574, PMCID: PMC12163267, DOI: 10.1177/23743735251346615.Peer-Reviewed Original ResearchVeterans Health AdministrationVA Medical CenterHeadache careCross-sectional studyFacility patientsVeterans AffairsVeterans Health Administration SurveyVeterans Health Administration carePatient satisfactionPatient-centered careMedical CenterDeliver high-qualityHealthcare experiencesHeadache visitsCare SurveyHealth AdministrationImprove satisfactionCareCenters of excellenceVeteransProvidersAnalyzed responsesSatisfactionResponse rateHigh-qualityDiagnostic Performance of Ultrasound for Diagnosing Midgut Malrotation and Volvulus in Children: A Multiinstitutional Retrospective Review.
Nguyen H, El-Ali A, Van Tassel D, Le Cacheux C, Sher A, Amirabadi A, Sammer M, Huang X, Riemann M, Wong K, Tutman J, Schiess D, Navarro O, Silva C. Diagnostic Performance of Ultrasound for Diagnosing Midgut Malrotation and Volvulus in Children: A Multiinstitutional Retrospective Review. American Journal Of Roentgenology 2025 PMID: 40499019, DOI: 10.2214/ajr.25.32660.Peer-Reviewed Original ResearchDiagnostic performance of ultrasoundPerformance of ultrasoundMidgut malrotationDiagnostic performanceSonographic signsUpper gastrointestinalUS sensitivityReference standardClinical follow-upEvaluate diagnostic performanceUS diagnostic performanceWilcoxon rank sum testRank sum testCross-sectional studyRetrospective reviewEquivocal studiesClinical dataFollow-upImaging testsBlinded reviewersMalrotationMedical recordsSum testChildren 0VolvulusEmergency Department Visits for Pelvic Organ Prolapse in the United States.
Markowitz M, St Martin B, Lundsberg L, Ringel N. Emergency Department Visits for Pelvic Organ Prolapse in the United States. Urogynecology 2025 PMID: 40454707, DOI: 10.1097/spv.0000000000001703.Peer-Reviewed Original ResearchEmergency department visitsEmergency department useEmergency department presentationsDepartment visitsPelvic organ prolapseDepartment useUtilization Project Nationwide Emergency Department SampleReduce emergency department useOrgan prolapseEmergency departmentHousehold incomeAnnual emergency department visitsNationwide Emergency Department SampleIncidence of emergency department visitsInternational Classification of DiseasesLower household incomeHealth care systemEmergency Department SampleClinical Modification codesCommunity outreach effortsClassification of DiseasesCross-sectional studyDiagnosis of pelvic organ prolapseOutpatient workflowUnited StatesTrends and Key Factors Associated With Racial and Ethnic Differences in Life’s Essential 8 Scores
Yang H, Huang C, Sawano M, Herrin J, Faridi K, Li Z, Spatz E, Krumholz H, Lu Y. Trends and Key Factors Associated With Racial and Ethnic Differences in Life’s Essential 8 Scores. JAMA Network Open 2025, 8: e2516663. PMID: 40531529, PMCID: PMC12177675, DOI: 10.1001/jamanetworkopen.2025.16663.Peer-Reviewed Original ResearchConceptsLife's Essential 8 scoreLife's Essential 8Cross-sectional studyWhite differencesEthnic differencesNational Health and Nutrition Examination SurveyHealth and Nutrition Examination SurveySleep health scoreNutrition Examination SurveyGroup-specific interventionsPrimary positive factorPhysical activityExamination SurveyHealth scoresBlack adultsWhite adultsMain OutcomesAsian adultsOverall scoreEvaluate trendsNicotine exposureEssential 8Blood lipidsAdultsEthnic groupsEpidemiology of Neuroendocrine Neoplasms in the US
Dasari A, Wallace K, Halperin D, Maxwell J, Kunz P, Singh S, Chasen B, Yao J. Epidemiology of Neuroendocrine Neoplasms in the US. JAMA Network Open 2025, 8: e2515798. PMID: 40553474, PMCID: PMC12188367, DOI: 10.1001/jamanetworkopen.2025.15798.Peer-Reviewed Original ResearchConceptsDuration prevalenceIncidence rateNational Cancer Institute's SurveillanceNeuroendocrine neoplasmsOverall survivalNeuroendocrine tumorsAge-adjusted incidenceSurvival trends of patientsAnnual age-adjusted incidenceNeuroendocrine neoplasm casesCross-sectional studyHighest incidence ratePrimary siteTrends of patientsInstitute's SurveillanceMain OutcomesPrevalence of neuroendocrine neoplasmsSmall bowelPrimary site of originFactors associated with survivalDiagnosis of early stage diseasePractice patternsPancreatic neuroendocrine tumorsGastrointestinal neuroendocrine tumorsEarly stage diseaseIndustry promotion of oncology drugs with accelerated approval that failed confirmatory trials.
Mooghali M, Ramachandran R, Mohammad A, Mitchell A. Industry promotion of oncology drugs with accelerated approval that failed confirmatory trials. Journal Of Clinical Oncology 2025, 43: 11029-11029. DOI: 10.1200/jco.2025.43.16_suppl.11029.Peer-Reviewed Original ResearchClinical benefitAccelerated approvalOncology drugsConfirmatory studiesConfirmatory trialsResults of confirmatory studiesFDA-accelerated approvalInfluence treatment recommendationsAccelerated approval drugsCross-sectional studyBelantamab mafodotinMedian durationMedian timeSurrogate markerPostapproval studiesVincristine sulfateTreatment recommendationsDrugs@FDA databaseIndustry paymentsFDA recommendationsU.S. FDADrugOncologyNegative resultsFDAAdoption of Broad Genomic Profiling in Patients With Cancer
Wang X, Rothen J, Huang S, Long J, Soulos P, Goldberg S, Mamtani R, Presley C, Kunst N, Ma S, Wang S, Gross C, Dinan M. Adoption of Broad Genomic Profiling in Patients With Cancer. JAMA Oncology 2025, 11: 666-668. PMID: 40244595, PMCID: PMC12006912, DOI: 10.1001/jamaoncol.2025.0499.Peer-Reviewed Original ResearchCareer transitions and practice patterns among international medical graduates in oncology workforce: A US nationwide analysis.
Xing J, Wang Q, Tang Y, Lu C, Chen F, Roy A, Deng L, Neupane K, Ardeshir Larijani F, Bekaii-Saab T, Aggarwal C, Lee A, Owonikoko T, Chavez Mac Gregor M, Bakouny Z, Gandhi S, Dizman N, Choueiri T, Perimbeti S, Jiang C. Career transitions and practice patterns among international medical graduates in oncology workforce: A US nationwide analysis. Journal Of Clinical Oncology 2025, 43: 9009-9009. DOI: 10.1200/jco.2025.43.16_suppl.9009.Peer-Reviewed Original ResearchInternational medical graduatesRural-Urban Continuum CodesCancer care deliveryOncology workforceMedical graduatesCare deliveryMedical oncologistsUS graduatesNCI-designated cancer centersDesignated cancer centersCross-sectional studyNon-metropolitan areasContinuum CodesWorkforce disparitiesUnderserved regionsSystemic barriersCareer stagesChi-square testPrimary specialtyPracticing medical oncologistsNCI centersStratified analysisAcademic affiliationPractice patternsPrimary outcomeThe Prevalence of Moral Distress and Moral Injury Among U.S. Veterans
Litz B, Walker H, Pietrzak R, Rusowicz-Orazem L. The Prevalence of Moral Distress and Moral Injury Among U.S. Veterans. Journal Of Psychiatric Research 2025 DOI: 10.1016/j.jpsychires.2025.06.031.Peer-Reviewed Original ResearchPrevalence of moral distressMoral distressU.S. veteransMoral injuryMental health challengesMental health concernsNationally representative sampleCross-sectional studyPMIE exposureWeighted prevalenceAssociated with significant functional impairmentSignificant functional impairmentInjury eventsHealth challengesRepresentative sampleVeteransDistressHealth concernFunctional impairmentAdverse outcomesPrevalencePMIEsInjuryKnowledgePanelU.S.“Easier Than Carrying Around a Computer and a 7-Week-Old”: Exploring Patients’ Reasons for Selection of Telehealth Modality for Contraceptive Counseling [ID 1538]
Paul R, Freeman E, Dorsey M, Reeves J, Madden T. “Easier Than Carrying Around a Computer and a 7-Week-Old”: Exploring Patients’ Reasons for Selection of Telehealth Modality for Contraceptive Counseling [ID 1538]. Obstetrics And Gynecology 2025, 145: 65s-65s. DOI: 10.1097/aog.0000000000005918.025.Peer-Reviewed Original ResearchContraceptive counselingContraceptive counseling visitsCross-sectional studyPatients' reasonsReproductive health servicesCounseling visitsPatientsPatient's lifestyleBivariate analysisSecondary analysisTelehealth visitsVisitsCounseling appointmentTelehealth appointmentsCounseling modalitiesCounselingFree-text responsesModalitiesHealth servicesTelehealth modalitiesAppointmentExploring Ethnic Disparities in Hypospadias Incidence: A Meta-Analysis of Epidemiological Studies
Santoso B, Situmorang G, Wahyudi I, Rodjani A, Saraiva L, Al-Shafai K, Abbas T, Raharja P. Exploring Ethnic Disparities in Hypospadias Incidence: A Meta-Analysis of Epidemiological Studies. Journal Of Pediatric Urology 2025 DOI: 10.1016/j.jpurol.2025.06.015.Peer-Reviewed Original ResearchEthnic disparitiesMeta-analysis of epidemiological studiesMeta-analysisHypospadias incidenceImprove healthcare outcomesDiverse populationsIncidence of hypospadiasCross-sectional studyCongenital anomaly prevalenceCase-control studyHealthcare outcomesReduce disparitiesJBI toolsPerinatal determinantsNon-white groupsCitation tracingStudy selectionData extractionSystematic reviewBias riskManual searchEpidemiological studiesRisk factorsDisparitiesEthnic variationsAccuracy of COVID-19 vaccination Self-report compared with data from VSD electronic health Records for Pregnant Women and non-pregnant Adults, 2021-2022
Stein A, Williams J, Hurley L, Breslin K, Kurlandsky K, Hambidge S, Nelson J, Fuller C, Crane B, Hanson K, Glenn S, Jazwa A, Reifler L. Accuracy of COVID-19 vaccination Self-report compared with data from VSD electronic health Records for Pregnant Women and non-pregnant Adults, 2021-2022. American Journal Of Epidemiology 2025, kwaf112. PMID: 40445214, DOI: 10.1093/aje/kwaf112.Peer-Reviewed Original ResearchElectronic health record dataElectronic health recordsSelf-reportHealth recordsVaccine Safety DatalinkAccuracy of electronic health recordsPregnant womenNon-pregnant adultsNon-Hispanic blacksSpanish-speaking respondentsVaccination statusEstimate vaccination ratesNon-pregnant peopleCross-sectional studySelf-reported vaccination statusSelf-reported dataSelf-report measuresAdult respondentsPrevention effortsVaccination ratesEstimates of sensitivityVaccination dataCOVID-19COVID-19 pandemicVaccination coveragePrivate Equity Among US Psychiatric Hospitals
Shields M, Yang Y, Busch S. Private Equity Among US Psychiatric Hospitals. JAMA Psychiatry 2025, 82: 701-708. PMID: 40397464, PMCID: PMC12096323, DOI: 10.1001/jamapsychiatry.2025.0689.Peer-Reviewed Original ResearchConceptsPsychiatric hospitalHospital staffingMeasures of case mixHealth care qualityNational quality measuresCross-sectional associationsInpatient psychiatric hospitalizationFreestanding psychiatric hospitalCross-sectional studyAverage length of stayRegistered nursesCare qualityStaffing ratiosHealth careLength of stayMain OutcomesPE ownershipPatient vulnerabilityCase-mixPatient daysAdjusted modelsLow staffPrivate equityStaffingHospitalSynthetic cannabinoid use and the acquired preparedness model
Pia T, Weinberger A. Synthetic cannabinoid use and the acquired preparedness model. American Journal On Addictions 2025 PMID: 40392442, DOI: 10.1111/ajad.70049.Peer-Reviewed Original ResearchAcquired preparedness modelFacets of impulsivitySC useSynthetic cannabinoidsAssociated with greater frequencySynthetic cannabinoid useSensation seekingAdult samplesCannabinoid useMediation analysisPreparedness modelU.S. sampleGreater frequencyPsychological effectsImpulseGeneral United StatesU.S. adultsPotential motivationsOnline surveyCross-sectional studyAdultsMotivationAddictionCannabinoidAnxietyNon-fatal Overdose and Associated Factors Among People Who Use Opioids: Findings From a Cross-sectional Study
Sujan M, Wickersham J, Khati A, Paudel K, Gautam K, Liautaud D, Crim H, Thapa A, Copenhaver M, Shrestha R. Non-fatal Overdose and Associated Factors Among People Who Use Opioids: Findings From a Cross-sectional Study. Journal Of Community Health 2025, 1-10. PMID: 40381076, DOI: 10.1007/s10900-025-01480-8.Peer-Reviewed Original ResearchNon-fatal overdoseOpioid dependenceCross-sectional studySuicidal ideationHistory of opioid useOpioid overdoseAlcohol use disorderNon-fatal opioid overdoseMental health symptomsAge of participantsParticipants self-reportedHarm reduction interventionsSocio-demographic characteristicsOpioid useEffective prevention strategiesUse disorderDepressive symptomsTargeted harm reduction interventionsHealth symptomsMultivariate logistic regression analysisLogistic regression analysisReduction interventionsOlder participantsCross-sector collaborationRisk of overdoseAcoustic-based machine learning approaches for depression detection in Chinese university students
Wei Y, Qin S, Liu F, Liu R, Zhou Y, Chen Y, Xiong X, Zheng W, Ji G, Meng Y, Wang F, Zhang R. Acoustic-based machine learning approaches for depression detection in Chinese university students. Frontiers In Public Health 2025, 13: 1561332. PMID: 40443925, PMCID: PMC12119278, DOI: 10.3389/fpubh.2025.1561332.Peer-Reviewed Original ResearchConceptsPatient Health Questionnaire-9Mel-frequency cepstral coefficientsLinear discriminant analysisMachine learning algorithmsAcoustic featuresLearning algorithmsIdentification of depressionMonitoring of depressionCross-sectional studyGlobal public health problemSHapley Additive exPlanationsDepression screeningSelf-report methodsPublic health problemIdentifying depressionLinear discriminant analysis modelDepression assessmentSupport vector classificationAutomated identificationMachine learning approachArea under the curveHealth problemsOpenSMILE toolkitLogistic regressionCepstral coefficientsCounty Incarceration Rate and Stroke Death: A Cross‐Sectional Study of the Influence of Physical Environment, Health Care Access, and Community Mental Distress
Sonderlund A, Wang E, Williams N, Horowitz C, Schoenthaler A, Holaday L. County Incarceration Rate and Stroke Death: A Cross‐Sectional Study of the Influence of Physical Environment, Health Care Access, and Community Mental Distress. Journal Of The American Heart Association 2025, 14: e039065. PMID: 40357666, PMCID: PMC12184567, DOI: 10.1161/jaha.124.039065.Peer-Reviewed Original ResearchConceptsPrimary care physiciansStroke deathsMental distressFood environmentImprisonment ratesRacial disparitiesPrimary care physician accessIncarceration ratesWhite populationHealth care accessMental health providersBlack populationCross-sectional designCross-sectional studyCare accessHealth providersCare physiciansPhysician accessAdjusted modelsTesting pathwayInfluence of physical environmentResults complement evidenceTest mediationDistressViolent crimeLiaison Committee on Medical Education’s Diversity Standards and Medical School Attrition
Nguyen M, Fancher T, Mason H, Shanab B, Venkataraman S, Chaudhry S, Desai M, McDade W, Boatright D. Liaison Committee on Medical Education’s Diversity Standards and Medical School Attrition. JAMA Health Forum 2025, 6: e250697. PMID: 40343717, PMCID: PMC12065036, DOI: 10.1001/jamahealthforum.2025.0697.Peer-Reviewed Original ResearchDiverse standardsCross-sectional study
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