2025
Disparities in the association of ambient air pollution with childhood asthma incidence in the ECHO consortium: A US-wide multi-cohort study
Wang V, Habre R, Ryan P, Coull B, Datta S, Luttmann-Gibson H, Blossom J, Just A, Schwartz J, Yanosky J, Aris I, Chandran A, Kress A, Breton C, Farzan S, Camargo C, Liang D, Ferrera A, Peterson A, Kerver J, Karr C, Leve L, Dabelea D, Karagas M, Bennett D, Nkoy F, Aschner J, O’Shea T, Lothrop N, McEvoy C, Knapp E, Schuh H, Miller R, Gold D, Zanobetti A, Smith P, Newby L, Adair L, Jacobson L, Catellier D, McGrath M, Douglas C, Duggal P, Knapp E, Kress A, Blackwell C, Mansolf M, Lai J, Ho E, Cella D, Gershon R, Macy M, Das S, Freedman J, Mallal S, McLean J, Shah R, Shilts M, Alshawabkeh A, Cordero J, Meeker J, Trasande L, Camargo C, Hasegawa K, Zhu Z, Sullivan A, Dabelea D, Perng W, Bekelman T, Wilkening G, Magzamen S, Moore B, Starling A, Rinehart D, Mitchell D, D’Sa V, Deoni S, Mueller H, Duarte C, Monk C, Canino G, Posner J, Murray T, Lugo-Candelas C, Dunlop A, Brennan P, Hockett C, Elliott A, Ferrara A, Croen L, Hedderson M, Ainsworth J, Bacharier L, Bendixsen C, Gern J, Gold D, Hartert T, Jackson D, Johnson C, Joseph C, Kattan M, Hershey G, Lemanske R, Lynch S, Miller R, O’Connor G, Ober C, Ownby D, Rivera-Spoljaric K, Ryan P, Seroogy C, Singh A, Wood R, Zoratti E, Habre R, Farzan S, Gilliland F, Hertz-Picciotto I, Bennett D, Schweitzer J, Schmidt R, LaSalle J, Hipwell A, Keenan K, Karr C, Bush N, LeWinn K, Sathyanarayana S, Zhao Q, Tylavsky F, Carroll K, Loftus C, Leve L, Ganiban J, Neiderhiser J, Weiss S, Litonjua A, McEvoy C, Spindel E, Tepper R, Newschaffer C, Lyall K, Volk H, Landa R, Ozonoff S, Piven J, Hazlett H, Pandey J, Schultz R, Dager S, Botteron K, Messinger D, Stone W, Ames J, O’Connor T, Miller R, Oken E, Hacker M, James-Todd T, O’Shea T, Fry R, Frazier J, Singh R, Rollins C, Montgomery A, Vaidya R, Joseph R, Washburn L, Gogcu S, Bear K, Rollins J, Hooper S, Taylor G, Jackson W, Thompson A, Daniels J, Hernandez M, Lu K, Msall M, Lenski M, Obeid R, Pastyrnak S, Jensen E, Sakai C, Santos H, Kerver J, Paneth N, Barone C, Elliott M, Ruden D, Fussman C, Herbstman J, Margolis A, Schantz S, Geiger S, Aguiar A, Tabb K, Strakovsky R, Woodruff T, Morello-Frosch R, Padula A, Stanford J, Porucznik C, Giardino A, Wright R, Wright R, Collett B, Baumann-Blackmore N, Gangnon R, Jackson D, McKennan C, Wilson J, Altman M, Aschner J, Stroustrup A, Merhar S, Moore P, Pryhuber G, Hudak M, Lyndaker A, Lampland A, Rochelson B, Jan S, Blitz M, Katzow M, Brown Z, Chiuzan C, Rafael T, Lewis D, Meirowitz N, Poindexter B, Gebretsadik T, Osmundson S, Straughen J, Eapen A, Cassidy-Bushrow A, Wegienka G, Sitarik A, Woodcroft K, Urquhart A, Levin A, Johnson-Hooper T, Davidson B, Ma T, Barrett E, Blaser M, Dominguez-Bello M, Horton D, Jimenez M, Rosen T, Palomares K, Avalos L, Zhu Y, Hunt K, Newman R, Bloom M, Alkis M, Roberts J, Mumford S, Burris H, DeMauro S, Yee L, Hamvas A, Olidipo A, Haddad A, Eiland L, Spillane N, Suri K, Fisher S, Goldstein J, Mithal L, DeRegnier R, Maitre N, Nguyen R, JaKa M, Sidebottom A, Paidas M, Potter J, Ruby N, Duthely L, Jayakumar A, Young K, Maldonado I, Miller M, Slaughter J, Keim S, Lynch C, Venkatesh K, Whitworth K, Symanski E, Northrup T, Mendez-Figueroa H, Mosquera R, Karagas M, Madan J, MacKenzie D, Lewis J, Rennie B, Leventhal B, Kim Y, Bishop S, Nozadi S, Luo L, Lester B, Marsit C, Everson T, Loncar C, McGowan E, Sheinkopf S, Carter B, Check J, Helderman J, Neal C, Smith L. Disparities in the association of ambient air pollution with childhood asthma incidence in the ECHO consortium: A US-wide multi-cohort study. Environmental Epidemiology 2025, 9: e398. PMID: 40520482, PMCID: PMC12160752, DOI: 10.1097/ee9.0000000000000398.Peer-Reviewed Original ResearchExposure to fine particulate matterIncident asthmaAsthma riskRisk of incident asthmaAssociation of ambient air pollutionProportion of Black residentsChild health outcomesChildhood asthma incidenceChildhood asthma riskInterquartile range increaseFine particulate matterAmbient air pollutionNitrogen dioxideHealth outcomesSociodemographic disparitiesAsthma incidenceAsthma diagnosisLack of participant diversityMulti-cohort studyResidential historyRange increaseParticipant diversitySociodemographic featuresBlack residentsTime trendsAssociation of delayed asthma diagnosis with asthma exacerbations in children
Wi C, Ryu E, King K, Kwon J, Bublitz J, Park M, Chiarella S, Greenwood J, Pongdee T, Myers L, Nordlund B, Sohn S, Sagheb E, Kshatriya B, Watson D, Liu H, Sheares B, Davis C, Schulz W, Juhn Y. Association of delayed asthma diagnosis with asthma exacerbations in children. Journal Of Allergy And Clinical Immunology Global 2025, 4: 100409. PMID: 40008091, PMCID: PMC11851198, DOI: 10.1016/j.jacig.2025.100409.Peer-Reviewed Original ResearchElectronic health recordsDiagnosis of asthmaAsthma diagnosisAsthma exacerbationsRisk of AEPredetermined Asthma CriteriaDiagnosis of childhood asthmaChildhood asthma managementIncreased riskCox proportional hazards modelsIncreased risk of AECare qualityAsthma outcomesHealth recordsProportional hazards modelAsthma managementChildhood asthmaBirth cohortAsthma severityDiagnosis statusIndex dateIdentifying childrenPrimary outcomeNatural language processing algorithmsHazards model
2021
Association of Vaping and Respiratory Health among Youth in the Population Assessment of Tobacco and Health (PATH) Study Wave 3
Cherian C, Buta E, Simon P, Gueorguieva R, Krishnan-Sarin S. Association of Vaping and Respiratory Health among Youth in the Population Assessment of Tobacco and Health (PATH) Study Wave 3. International Journal Of Environmental Research And Public Health 2021, 18: 8208. PMID: 34360499, PMCID: PMC8346152, DOI: 10.3390/ijerph18158208.Peer-Reviewed Original ResearchConceptsDry coughRespiratory manifestationsHigher oddsExercise-induced wheezingPulmonary clinical manifestationsSerious pulmonary complicationsNicotine product useLogistic regression modelsPulmonary complicationsAsthma diagnosisInhaler useWave 3Clinical manifestationsRespiratory healthEarly recognitionHealth SurveyTobacco useClinical effortsLifetime numberPrevention effortsPast yearPopulation AssessmentWheezingProduct useCough
2020
Discovery and Mediation Analysis of Cross-Phenotype Associations Between Asthma and Body Mass Index in 12q13.2
Salinas YD, Wang Z, DeWan AT. Discovery and Mediation Analysis of Cross-Phenotype Associations Between Asthma and Body Mass Index in 12q13.2. American Journal Of Epidemiology 2020, 190: 85-94. PMID: 32700739, PMCID: PMC7784522, DOI: 10.1093/aje/kwaa144.Peer-Reviewed Original ResearchConceptsBody mass indexMass indexComorbidity of asthmaWhite British subjectsCross-phenotype associationsAdult asthmaAsthma diagnosisAsthmaConfounder adjustmentAsthma associationsBMI associationsMediation analysisLimited evidenceCandidate gene studiesBMIObesityUK BiobankAssociationDiagnosisTwin studiesAgeFurther characterizationComorbiditiesConfounders
2017
Recommendations for a Clinical Decision Support System for Work-Related Asthma in Primary Care Settings
Harber P, Redlich CA, Hines S, Filios MS, Storey E. Recommendations for a Clinical Decision Support System for Work-Related Asthma in Primary Care Settings. Journal Of Occupational And Environmental Medicine 2017, 59: e231-e235. PMID: 29023337, PMCID: PMC6282164, DOI: 10.1097/jom.0000000000001182.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsWork-related asthmaElectronic health recordsPossible work-related asthmaPrimary care health care providersMortality of asthmaPrimary care settingSpecific clinical conditionsAmerican Thoracic SocietyHealth care providersClinical decision support systemAsthma symptomsAsthma diagnosisThoracic SocietyPossible referralCare settingsClinical conditionsCare providersAsthmaAvailable guidelinesFurther evaluationHealth recordsClinical decision support approachEHR systemsPositive responseSpecific recommendationsA web-based educational video to improve asthma knowledge for limited English proficiency Latino caregivers
Riera A, Ocasio A, Tiyyagura G, Thomas A, Goncalves P, Krumeich L, Ragins K, Trevino S, Vaca FE. A web-based educational video to improve asthma knowledge for limited English proficiency Latino caregivers. Journal Of Asthma 2017, 54: 624-631. PMID: 27780380, PMCID: PMC7244941, DOI: 10.1080/02770903.2016.1251597.Peer-Reviewed Original ResearchConceptsCaregiver asthma knowledgeAsthma knowledgeAsthma careAsthma diagnosisQuality asthma carePediatric asthma careAsthma action planLatino caregiversAsthma knowledge questionnaireAsthma knowledge scoresEducational videoLEP caregiversChild asthma diagnosisPersistent asthmaED utilizationED encountersMedication usageInterventional studyActivity limitationsChildren 2Knowledge questionnaireKnowledge scoreCaregiversMean scoreHigh school diploma
2016
Allergy-specific Phenome-Wide Association Study for Immunogenes in Turkish Children
Karaca S, Civelek E, Karaca M, Sahiner UM, Ozgul RK, Kocabas CN, Polimanti R, Sekerel BE. Allergy-specific Phenome-Wide Association Study for Immunogenes in Turkish Children. Scientific Reports 2016, 6: 33152. PMID: 27624002, PMCID: PMC5021980, DOI: 10.1038/srep33152.Peer-Reviewed Original ResearchConceptsHypertonic saline challenge testTurkish childrenAllergic airway inflammationPhenome-wide association studySkin prick testRole of immunogeneticsCross-sectional studyDifferent immune functionsAllergic bronchitisCD14 rs2569190Airway inflammationAtopic marchPrick testAsthma diagnosisLung functionBlood testsIL4 rs2243250Immune functionChallenge testAssociation studiesADAM33ComorbiditiesChildrenAssociationAsthma
2015
Guidance on the diagnosis and management of asthma among adults in resource limited settings
Kirenga BJ, Schwartz JI, de Jong C, van der Molen T, Okot-Nwang M. Guidance on the diagnosis and management of asthma among adults in resource limited settings. African Health Sciences 2015, 15: 1189-1199. PMID: 26958020, PMCID: PMC4765426, DOI: 10.4314/ahs.v15i4.18.Peer-Reviewed Original ResearchConceptsResource limited settingsManagement of asthmaLimited settingsInternational asthma guidelinesQuality asthma careRecurrent respiratory symptomsLikelihood of asthmaCurrent wheezeSteroid therapyAsthma guidelinesSalbutamol administrationAsthma careClinical improvementExpiratory volumeRespiratory symptomsAsthma diagnosisAllergic diseasesPatient educationClinical dataFamily historyAsthmaSeverity gradingAssessment of controlHealth providersInternational guidelines
2014
Findings from a community-based asthma education fair for Latino caregivers
Riera A, Ocasio A, Goncalves P, Krumeich L, Katz KH, Trevino S, Vaca FE. Findings from a community-based asthma education fair for Latino caregivers. Journal Of Asthma 2014, 52: 71-80. PMID: 25019349, DOI: 10.3109/02770903.2014.944982.Peer-Reviewed Original ResearchMeSH KeywordsAbsenteeismAdolescentAdrenal Cortex HormonesAdrenergic beta-AgonistsAdultAmbulatory Care FacilitiesAnti-Asthmatic AgentsAsthmaCaregiversChildChild, PreschoolCommunity-Based Participatory ResearchEmergency Service, HospitalHealth EducationHealth Knowledge, Attitudes, PracticeHispanic or LatinoHospitalizationHumansInfantLanguageMetered Dose InhalersMiddle AgedQuality of LifeResidence CharacteristicsYoung AdultConceptsLEP caregiversCaregiver qualityMedication recognitionPediatric Asthma Caregiver's QualityEmergency department visitsPeak flow meterIndividualized action plansWilcoxon signed-rank testPACQLQ scoresClinic visitsAsthma diagnosisDepartment visitsHealthcare utilizationQOL improvementChildren 1Life QuestionnaireCaregiver QOLSigned-rank testActivity limitationsCaregivers' abilityMcNemar testSchool absenteeismLatino caregiversCaregiversBaseline data
2011
Association of maternal anemia with increased wheeze and asthma in children
Triche EW, Lundsberg LS, Wickner PG, Belanger K, Leaderer BP, Bracken MB. Association of maternal anemia with increased wheeze and asthma in children. Annals Of Allergy Asthma & Immunology 2011, 106: 131-139.e1. PMID: 21277514, PMCID: PMC3073499, DOI: 10.1016/j.anai.2010.11.007.Peer-Reviewed Original ResearchConceptsMaternal anemiaEarly-onset transientRespiratory health outcomesChildren of womenOffspring of mothersRespiratory disease developmentChildren of mothersYears of ageEarly childhoodAge 3Delivery hospitalizationsRecurrent wheezeCurrent asthmaAsthma diagnosisChildhood asthmaInfant wheezeMaternal nutritionRespiratory healthWheezeAsthmaAnemiaHealth outcomesPregnancyAnemia diagnosisMicronutrient status
2006
The Epidemiology of Asthma During Pregnancy: Prevalence, Diagnosis, and Symptoms
Kwon HL, Triche EW, Belanger K, Bracken MB. The Epidemiology of Asthma During Pregnancy: Prevalence, Diagnosis, and Symptoms. Immunology And Allergy Clinics Of North America 2006, 26: 29-62. PMID: 16443142, DOI: 10.1016/j.iac.2005.11.002.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsPregnant womenLarge prospective cohort studyEpidemiology of asthmaProspective cohort studySelf-reported asthmaPopulation-level improvementsAsthma controlCohort studyAsthma diagnosisAsthma attacksCommon conditionPrevalence ratesClinical involvementAsthmaNational dataPregnancyPrevalenceDiagnosisWomenUnited StatesPopulation characteristicsRepresentative dataPrevious yearFurther researchFurther characterization
2003
Asthma symptoms, severity, and drug therapy: a prospective study of effects on 2205 pregnancies.
Bracken MB, Triche EW, Belanger K, Saftlas A, Beckett WS, Leaderer BP. Asthma symptoms, severity, and drug therapy: a prospective study of effects on 2205 pregnancies. Obstetrics And Gynecology 2003, 102: 739-52. PMID: 14551004, DOI: 10.1016/s0029-7844(03)00621-5.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnti-Asthmatic AgentsAnti-Inflammatory AgentsAsthmaBirth WeightCase-Control StudiesConnecticutFemaleFetal Growth RetardationFetal Membranes, Premature RuptureHumansInfant, Low Birth WeightInfant, NewbornMassachusettsPregnancyPregnancy ComplicationsPregnancy OutcomeProspective StudiesRisk FactorsSeverity of Illness IndexSteroidsTheophyllineConceptsAsthma symptomsOral steroidsAsthma diagnosisPreterm deliveryPregnant womenHistory of asthmaIntrauterine growth restrictionIUGR infantsAsthma guidelinesAsthma historyController medicationsModerate asthmaAsthma therapyPregnant patientsSymptomatic patientsAsthma severityFetal effectsSymptomatic womenProspective studyDrug therapyGrowth restrictionAsthmaSymptomsMedicationsDiagnosisAsthma Symptoms, Severity, and Drug Therapy: A Prospective Study of Effects on 2205 Pregnancies
Bracken M, Triche E, Belanger K, Saftlas A, Beckett W, Leaderer B. Asthma Symptoms, Severity, and Drug Therapy: A Prospective Study of Effects on 2205 Pregnancies. Obstetrics And Gynecology 2003, 102: 739. DOI: 10.1097/00006250-200310000-00016.Peer-Reviewed Original ResearchAsthma symptomsOral steroidsAsthma diagnosisPreterm deliveryPregnant womenHistory of asthmaIntrauterine growth restrictionIUGR infantsAsthma guidelinesAsthma historyController medicationsModerate asthmaPregnant patientsAsthma therapySymptomatic patientsAsthma severityFetal effectsSymptomatic womenProspective studyDrug therapyGrowth restrictionΒ2 agonistsAsthmaSymptomsMedications
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