2025
Ensuring Timely Pulmonary Follow-up after an Inpatient Asthma Hospitalization: A Quality Improvement Initiative
Chandrasekar L, Schaffer H, Godse S, Grossman M, Chen L, Brumer E. Ensuring Timely Pulmonary Follow-up after an Inpatient Asthma Hospitalization: A Quality Improvement Initiative. Pediatric Quality And Safety 2025, 10: e815. PMID: 40371048, PMCID: PMC12077554, DOI: 10.1097/pq9.0000000000000815.Peer-Reviewed Original ResearchQuality improvement initiativesFollow-up appointmentsImprovement initiativesAttendance ratesAsthma exacerbationsTimely outpatient follow-upAppointment attendance ratesAsthma care guidelinesDays of hospital dischargeFollow-upPulmonary follow-upInconsistent careAcute asthma exacerbationAsthma hospitalizationsCare guidelinesVisit attendanceOutpatient follow-upPediatric intensive care unitActivity remindersAsthma controlOutcome measuresMultidisciplinary teamHospital dischargePrevent future episodesPulmonary consultationUpdate on the utilization of complementary therapies by adolescents with asthma in an urban population
Soffer G, Feinberg T, Kroll H, Reznik M. Update on the utilization of complementary therapies by adolescents with asthma in an urban population. Journal Of Asthma 2025, ahead-of-print: 1-9. PMID: 40040497, DOI: 10.1080/02770903.2025.2475451.Peer-Reviewed Original ResearchAsthma Control TestCAM useUtilization of complementary therapiesPrevalence of CAM usePrescription adherenceEfficacy of CAMHealth-promoting behaviorsPrimary care clinicsElectronic health recordsCAM utilizationCare clinicsActivity prescriptionHealth recordsAlternative medicineComplementary therapyAsthma managementLack of associationOutpatient specialtyAsthma controlSelf-reportAsthma severityLogistic regressionMind-bodyUrban adolescentsDemographic information
2024
Caregivers of children with asthma alarmed by climate change: a cross‐sectional study
Godse S, Shabanova V, Ragavan M, Mitchell M, Chen L, Flom J, Sheares B. Caregivers of children with asthma alarmed by climate change: a cross‐sectional study. Pediatric Pulmonology 2024, 59: 3677-3685. PMID: 39323113, DOI: 10.1002/ppul.27288.Peer-Reviewed Original ResearchCaregivers of childrenCross-sectional studyClimate change-related health risksHealth impacts of climate changeInforming public health policyPublic health policiesReports adverse impactsRespiratory health impactsCaregiver perspectivesCaregiver perceptionsChild's asthmaHealth policyChild healthChild's doctorHealth harmsHealth risksCaregiversWorsening asthma controlAsthma controlAir pollutionAdverse health effectsPulmonology clinicSurvey instrumentUS settingHealth effectsNeighborhood Socioeconomic Context Predicts Pediatric Asthma Exacerbation
Kranjac A, Kain Z, Ehwerhemuepha L, Weiss M, Jenkins B. Neighborhood Socioeconomic Context Predicts Pediatric Asthma Exacerbation. Clinical Pediatrics 2024, 64: 310-318. PMID: 39044420, DOI: 10.1177/00099228241262997.Peer-Reviewed Original ResearchNon-Hispanic Black residentsAsthma exacerbationsElectronic medical record dataLevels of ambient air pollutionNeighborhood-level factorsAssociated with greater oddsMedical record dataAmbient air pollutionIndividual-level factorsPlace-based initiativesProportion of female-headed householdsAsthma managementNeighborhood characteristicsGreater oddsAsthma controlUncontrolled asthmaBlack residentsFemale-headed householdsRecord dataInadequate disease controlMultilevel modeling techniquesPediatric patientsResidential characteristicsAsthmaIndividual levelThe role of positive affect in asthma control and symptom severity in adolescents
Jenkins B, Martin L, Halterman J, Moskowitz J, Glynn L, Tirakitsoontorn P, Kamath S, Kain Z. The role of positive affect in asthma control and symptom severity in adolescents. Journal Of Adolescence 2024, 96: 1673-1683. PMID: 39015022, DOI: 10.1002/jad.12373.Peer-Reviewed Original ResearchPositive affectSymptom severityAsthma symptom severityArousal componentAsthma controlEffect of positive affectPsychological triggersHigher levels of stressSurveyed 4 timesLevels of stressModerate to severe asthmaAffectAsthma triggersSubscale componentsAdolescentsPatient stressSymptomsWellbeingAsthmaSeverityAssociationSevere asthmaHigher levelsArousalWhat Education Should Be Provided to All Parents of Children With Asthma to Help With Day-to-Day Management?
Tolomeo C. What Education Should Be Provided to All Parents of Children With Asthma to Help With Day-to-Day Management? 2024, 203-206. DOI: 10.1201/9781003523611-47.Peer-Reviewed Original ResearchAsthma educationAsthma self-management education programSelf-management education programWritten asthma action planAsthma action planNational Asthma Education and Prevention Program's Expert Panel Report 3Expert Panel Report 3Self-monitoring symptomsManagement of asthmaParents of ChildrenEducational interventionAsthma medicationsEPR-3Medical carePediatric settingAsthma controlDay-to-day managementReport 3Education programsNAEPPGuidelines stateAction planAsthmaDevice techniqueEducationWhat Do Parents of My Patients Need to Know About Asthma and Its Management?
Tolomeo C. What Do Parents of My Patients Need to Know About Asthma and Its Management? 2024, 195-197. DOI: 10.1201/9781003523611-45.Peer-Reviewed Original ResearchAsthma control in the United States Relationships between short-acting β2-agonist and systemic corticosteroid use
Chupp G, Murphy K, Gandhi H, Gilbert I, Bleecker E. Asthma control in the United States Relationships between short-acting β2-agonist and systemic corticosteroid use. Annals Of Allergy Asthma & Immunology 2024, 133: 302-309. PMID: 38740134, DOI: 10.1016/j.anai.2024.05.003.Peer-Reviewed Original ResearchMild to moderate diseaseSystemic corticosteroidsMild-to-moderateSevere asthmaUncontrolled asthmaSystemic corticosteroid exposureSystemic corticosteroid useAsthma control assessmentCorticosteroid useExacerbation historyRetrospective analysisSABA useUS patientsPrescription fillsPatientsLongitudinal accessAsthma controlDisease severityAsthmaDiseaseExacerbationPearson correlation coefficientHigh symptom burdenPatient severitySymptom burden
2023
Effect of tezepelumab on healthcare utilization in patients with severe, uncontrolled asthma The NAVIGATOR study
Menzies-Gow A, Bourdin A, Chupp G, Israel E, Hellqvist Å, Hunter G, Roseti S, Ambrose C, Llanos J, Cook B, Corren J, Colice G. Effect of tezepelumab on healthcare utilization in patients with severe, uncontrolled asthma The NAVIGATOR study. Annals Of Allergy Asthma & Immunology 2023, 131: 343-348.e2. PMID: 37263380, DOI: 10.1016/j.anai.2023.05.028.Peer-Reviewed Original ResearchConceptsExacerbation-related hospitalizationsHealthcare utilizationUncontrolled asthmaNAVIGATOR studyAsthma-related healthcare utilizationEffect of tezepelumabPatient healthcare utilizationRecipients of placeboThymic stromal lymphopoietinHealth-related qualityIntensive care daysHuman monoclonal antibodySubcutaneous tezepelumabAsthma controlAsthma exacerbationsLung functionSpecialist visitsEmergency departmentCare daysOverall burdenTezepelumabMAIN OUTCOMEPlaceboAmbulance transportHospitalizationDupilumab improves long‐term outcomes in patients with uncontrolled, moderate‐to‐severe GINA‐based type 2 asthma, irrespective of allergic status
Rabe K, Pavord I, Busse W, Chupp G, Izuhara K, Altincatal A, Gall R, Pandit‐Abid N, Deniz Y, Rowe P, Jacob‐Nara J, Radwan A. Dupilumab improves long‐term outcomes in patients with uncontrolled, moderate‐to‐severe GINA‐based type 2 asthma, irrespective of allergic status. Allergy 2023, 78: 2148-2156. PMID: 37073882, DOI: 10.1111/all.15747.Peer-Reviewed Original ResearchConceptsParent study baselineType 2 inflammationPre-bronchodilator FEVAsthma exacerbation rateType 2 asthmaAllergic asthmaExacerbation rateSevere asthma exacerbation ratesSevere type 2 asthmaAsthma Control Questionnaire scoreACQ-5 scoresReduced exacerbation ratesLong-term outcomesLong-term treatmentAllergic statusDupilumab efficacyGINA guidelinesQUEST studyWeek 96Asthma controlUncontrolled asthmaWeek 48Allergic phenotypeLung functionQuestionnaire scores
2021
Asthma and Three Colinear Comorbidities: Obesity, OSA, and GERD
Althoff M, Ghincea A, Wood L, Holguin F, Sharma S. Asthma and Three Colinear Comorbidities: Obesity, OSA, and GERD. The Journal Of Allergy And Clinical Immunology In Practice 2021, 9: 3877-3884. PMID: 34506967, PMCID: PMC8578370, DOI: 10.1016/j.jaip.2021.09.003.Peer-Reviewed Original ResearchConceptsGastroesophageal reflux diseaseObstructive sleep apneaDevelopment of asthmaAsthma controlReflux diseaseCommon comorbiditiesSleep apneaInflammatory pathwaysRisk factorsAsthmaComorbiditiesDiseaseHeterogeneous phenotypesObesityHigh rateComplex diseasesManagement recommendationsEndotypesApneaPatientsPathophysiologyGERDEpidemiologyOSA
2020
Development of the Asthma Impairment and Risk Questionnaire (AIRQ): A Composite Control Measure
Murphy K, Chipps B, Beuther D, Wise R, McCann W, Gilbert I, Eudicone J, Gandhi H, Harding G, Coyne K, Zeiger R, Board P, Kobernick A, Mohammad A, Cherry A, Fein A, Gaines A, Ramsey A, Michaud A, Palmer A, Kim A, Smith A, White A, Ricci A, Kettelhut B, Modena B, Stone B, Rolston B, Schnapf B, Krajicek B, Kraft C, Hopkins C, Natalie C, Anderson C, Czajkowski C, Arce D, Hamlin D, Hill D, Mares D, Pham D, Liao D, Simmons D, Johnson D, Jhaveri D, Maselli D, Kerwin E, Schuman E, Sher E, Bleecker E, Rakowski E, Hsu F, Averill F, Barsanti F, Gross G, Chupp G, Head G, Nasir H, Lee H, Barjaktarevic I, Cook J, Krainson J, Pearl J, Bellak J, Perez-Fernandez J, Rehm J, Trevor J, Most J, Hanson J, Blessing-Moore J, Biller J, Gedell J, Southard J, Chancellor J, Ilowite J, Romeo J, Mercado J, Fisher J, Greiwe J, Gregory K, Nadeau K, Shenoy K, Tan L, Stefanowicz L, Humes L, Bowers L, O’Connor M, Perez M, White M, Hegewald M, Wilson M, Sikora M, Morganroth M, Smith M, Farooqui N, Lesch N, Jain N, Parikh N, Hartog N, Luthin P, Stewart P, O’Connor P, Schochet P, Goldberg P, Patel P, Chinthrajah R, Sidhu R, Ayinla R, Brown R, Stadtler R, Wachs R, Balkissoon R, Duplantier R, Puente R, Settipane R, Mustafa S, Surani S, Jawad S, Adams S, Villegas S, Al-Farra S, Subramanian S, Bains S, Kelsen S, Wise S, Estrella-Eades S, Smith S, Qureshi T, Chen T, Kelbel T, Miller T, Jain V, Soong W, Soler X, Mattar Z. Development of the Asthma Impairment and Risk Questionnaire (AIRQ): A Composite Control Measure. The Journal Of Allergy And Clinical Immunology In Practice 2020, 8: 2263-2274.e5. PMID: 32387166, DOI: 10.1016/j.jaip.2020.02.042.Peer-Reviewed Original ResearchConceptsAsthma controlAsthma Control Test scoresAsthma control toolPhysician-diagnosed asthmaCut pointsLogistic regression analysisAsthma impairmentExacerbation historyAsthma severityFuture exacerbationsTest-retest reliabilityRisk QuestionnaireSymptom impairmentAsthmaSpecialty practicePatientsRisk questionsGlobal InitiativeImpairmentAirQRisk increaseCharacteristic curveExacerbationRegression analysisComposite measureAssessing Asthma Control in the United States by Examining the Relationships Between Short-Acting Beta 2 -Agonist and Systemic Corticosteroid Use
Bleecker E, Murphy K, Gandhi H, Gilbert I, Chupp G. Assessing Asthma Control in the United States by Examining the Relationships Between Short-Acting Beta 2 -Agonist and Systemic Corticosteroid Use. 2020, a1818-a1818. DOI: 10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a1818.Peer-Reviewed Original Research
2019
Biomarkers, Targeted Therapies, Biologics, and Bronchial Thermoplasty
Mohan A, Grace J, Mainardi A, Chupp G, Lugogo N. Biomarkers, Targeted Therapies, Biologics, and Bronchial Thermoplasty. Respiratory Medicine 2019, 123-153. DOI: 10.1007/978-3-030-20812-7_8.Peer-Reviewed Original ResearchSevere asthmaBronchial thermoplastyBiologic therapySurrogate markerOral corticosteroid exposureHeterogeneous inflammatory diseaseIdentification of respondersMultiple pathologic mechanismsAsthma controlCorticosteroid exposureDisease activityAsthma symptomsAsthma therapyPredictive markerInflammatory diseasesPrognostic markerTargeted therapyCurrent biomarkersPathologic mechanismsAsthmaDrug AdministrationParticular patientPatientsTherapyAdvanced therapiesAddressing Comorbidities in Difficult Asthma
Kwah J, Peters A, Khatri S. Addressing Comorbidities in Difficult Asthma. Respiratory Medicine 2019, 55-74. DOI: 10.1007/978-3-030-20812-7_4.Peer-Reviewed Original ResearchTreat asthmaAsthma controlAspirin-exacerbated respiratory diseaseChronic oral corticosteroidsPoor asthma controlVocal cord dysfunctionObstructive sleep apneaLaryngopharyngeal reflux diseaseManagement of patientsSignificant symptomatic reliefOral corticosteroidsDifficult asthmaReflux diseaseAllergic rhinitisChronic rhinosinusitisCord dysfunctionSymptomatic reliefComorbid conditionsSleep apneaNasal polypsRespiratory diseaseAsthmaCorticosteroidsPatientsDisease
2018
Implementation of the Asthma Control Test in Primary Care to Improve Patient Outcomes
Banasiak NC. Implementation of the Asthma Control Test in Primary Care to Improve Patient Outcomes. Journal Of Pediatric Health Care 2018, 32: 591-599. PMID: 30104128, DOI: 10.1016/j.pedhc.2018.05.004.Peer-Reviewed Original ResearchConceptsAsthma Control TestPrimary care practicesAsthma controlCare practicesChildhood Asthma Control TestManagement of patientsMajor chronic diseasesPediatric resident physiciansPost-implementation studyControl testsEvidence-based projectMedication therapyPediatric populationBlood InstituteNational HeartPrimary careChronic diseasesPatient outcomesAsthmaPatientsResident physiciansAdvanced practicePeriodic assessmentChildrenEducational programs
2017
Improving the asthma disparity gap with legal advocacy? A qualitative study of patient-identified challenges to improve social and environmental factors that contribute to poorly controlled asthma
Harris DA, Mainardi A, Iyamu O, Rosenthal MS, Bruce RD, Pisani MA, Redlich CA. Improving the asthma disparity gap with legal advocacy? A qualitative study of patient-identified challenges to improve social and environmental factors that contribute to poorly controlled asthma. Journal Of Asthma 2017, 55: 924-932. PMID: 28872933, DOI: 10.1080/02770903.2017.1373393.Peer-Reviewed Original ResearchConceptsPoor symptom controlSymptom controlAsthma Control Test scoresCommon barriersCommunity health centersWork-related symptomsEnvironmental risk factorsPercent of participantsCommunity-engaged approachAsthmatic adultsAsthma controlRisk factorsAsthma triggersHealth centersImproved outcomesMedical careDisparity gapStudy participantsPerson interviewsLack of awarenessAsthmaPatientsConstant comparative methodEnvironmental factorsAdultsTrends in Omalizumab Utilization for Asthma: Evidence of Suboptimal Patient Selection
Jeffery MM, Shah ND, Karaca-Mandic P, Ross JS, Rank MA. Trends in Omalizumab Utilization for Asthma: Evidence of Suboptimal Patient Selection. The Journal Of Allergy And Clinical Immunology In Practice 2017, 6: 1568-1577.e4. PMID: 28958746, DOI: 10.1016/j.jaip.2017.07.034.Peer-Reviewed Original ResearchConceptsOmalizumab initiationAsthma controlICS-LABAPatient selectionLow adherenceBetter asthma controlCohort of nonusersSuboptimal patient selectionPoor asthma controlLow adherence ratesPatient-level characteristicsLarge US databaseMedicare Advantage beneficiariesAsthma biologicsExacerbation frequencyOmalizumab useIncident useComparison cohortICS/Medication adherenceAdherence ratesPrevalent usersAdministrative claimsAsthmaUtilization trendsMepolizumab Significantly Improves Health Status and Asthma Control in Severe Eosinophilic Asthma: The Musca Study - a Phase IIIb Randomized, Placebo-Controlled Trial
Chupp G, Bradford E, Albers F, Bratton D, Wang-Jairaj J, Nelsen L, Trevor J, Magnan A, Brinke A. Mepolizumab Significantly Improves Health Status and Asthma Control in Severe Eosinophilic Asthma: The Musca Study - a Phase IIIb Randomized, Placebo-Controlled Trial. Journal Of Allergy And Clinical Immunology 2017, 139: ab380. DOI: 10.1016/j.jaci.2016.12.911.Peer-Reviewed Original Research
2012
Emergency department treatment of adults with acute asthma exacerbations: Effect on exhaled nitric oxide levels
Silverberg J, Rodenas M, Sinert R, Joks R. Emergency department treatment of adults with acute asthma exacerbations: Effect on exhaled nitric oxide levels. Allergy & Asthma Proceedings 2012, 33: 514-518. PMID: 23394510, DOI: 10.2500/aap.2012.33.3613.Peer-Reviewed Original ResearchConceptsExhaled nitric oxide levelsAcute asthma exacerbationPeak expiratory flowEmergency departmentNitric oxide levelsAsthma exacerbationsAsthma controlNoninvasive marker of airway inflammationPeripheral blood leukocyte numberTreatment of acute asthma exacerbationsKings County Hospital CenterAssociated with serum IgE levelsFall pollen seasonMarker of airway inflammationTobacco smoking historyAsthma Control TestED treatmentAbsolute eosinophil countAssociated with oxygen saturationSerum IgE levelsAdult asthmatic subjectsBlood leukocyte numbersEmergency department treatmentTreatment of adultsMeasures of inflammation
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