2025
Exposure measurement error in air pollution health effect studies: a pooled analysis of personal exposure validation studies in 17 communities across the United States
Zhang B, Eum K, Szpiro A, Zhang N, Hernández-Ramírez R, Spiegelman D, Wang M, Suh H. Exposure measurement error in air pollution health effect studies: a pooled analysis of personal exposure validation studies in 17 communities across the United States. International Journal Of Environmental Health Research 2025, ahead-of-print: 1-11. PMID: 40191987, DOI: 10.1080/09603123.2025.2488481.Peer-Reviewed Original ResearchAmbient concentrationsNearest monitorExposure measurement errorMeasurements of PM<sub>2.5</sub>Personal PM<sub>2.5</sub>Air pollution health effects studiesPersonal exposureHealth effects of air pollutionEffects of air pollutionHealth effects studiesAdverse health effectsExposure surrogatesAir pollutionHealth risksCdExposure indicatorsNiAssociated with health risksLinear mixed modelsQuantify measurement errorMixed modelsConcentrationExposurePbMonthly averages
2024
Sleep: Architecture, Deprivation, and Propofol-Induced Sleep.
McClintock K, Mercurio A, Reilly D, Cosgrove M, Rachler R. Sleep: Architecture, Deprivation, and Propofol-Induced Sleep. AANA Journal 2024, 92: 459-470. PMID: 39601855.Peer-Reviewed Original ResearchLongitudinal biomonitoring of mycotoxin exposure during pregnancy in the Yale Pregnancy Outcome Prediction Study
Krausová M, Ayeni K, Gu Y, Borutzki Y, O'Bryan J, Perley L, Silasi M, Wisgrill L, Johnson C, Warth B. Longitudinal biomonitoring of mycotoxin exposure during pregnancy in the Yale Pregnancy Outcome Prediction Study. Environment International 2024, 194: 109081. PMID: 39615253, DOI: 10.1016/j.envint.2024.109081.Peer-Reviewed Original ResearchPregnancy Outcome Prediction studyPregnant womenOutcome prediction studiesTandem mass spectrometryLiquid chromatography tandem mass spectrometryPlasma matrixUrine methodMass spectrometryUrinary dataHuman biomonitoringCarcinogen ochratoxin ASerum methodNeoplastic effectsSerumLC-MS/MSMonomethyl etherUnborn childSerum samplesTime pointsUrineBiomarkers of exposurePregnancyAdverse health effectsWomenHuman biomonitoring guidance valuesCaregivers of children with asthma alarmed by climate change: a cross‐sectional study
Godse S, Shabanova V, Ragavan M, Mitchell M, Chen L, Flom J, Sheares B. Caregivers of children with asthma alarmed by climate change: a cross‐sectional study. Pediatric Pulmonology 2024, 59: 3677-3685. PMID: 39323113, DOI: 10.1002/ppul.27288.Peer-Reviewed Original ResearchCaregivers of childrenCross-sectional studyClimate change-related health risksHealth impacts of climate changeInforming public health policyPublic health policiesReports adverse impactsRespiratory health impactsCaregiver perspectivesCaregiver perceptionsChild's asthmaHealth policyChild healthChild's doctorHealth harmsHealth risksCaregiversWorsening asthma controlAsthma controlAir pollutionAdverse health effectsPulmonology clinicSurvey instrumentUS settingHealth effectsBetween and within-city variations of PM2.5 oxidative potential in five cities in Colombia
Rojas N, Agudelo-Castañeda D, Bustos D, Godri Pollitt K, Gao D, Rodriguez-Villamizar L. Between and within-city variations of PM2.5 oxidative potential in five cities in Colombia. Air Quality, Atmosphere & Health 2024, 18: 127-140. DOI: 10.1007/s11869-024-01632-0.Peer-Reviewed Original ResearchPM2.5 mass concentrationsUltrasonic Personal Aerosol SamplerMass concentrationFine particulate matterAmbient PM2.5 samplesHealth exposure metricWithin-city variationAdverse health effectsPM2.5 OPPM2.5 samplesOP metricsBackground siteParticulate matterPM2.5Residential sitesIndustrial sitesOxidation potentialSite typesPersonal aerosol samplersExposure metricsHealth effectsAerosol samplerM-3ConcentrationSitesAssociation between Personal Abiotic Airborne Exposures and Body Composition Changes among Healthy Adults (60–69 Years Old): A Combined Exposome-Wide and Lipidome Mediation Approach from the China BAPE Study
Sun P, Guo X, Ding E, Li C, Ren H, Xu Y, Qian J, Deng F, Shi W, Dong H, Lin E, Guo P, Fang J, Zhang Q, Zhao W, Tong S, Lu X, Pollitt K, Shi X, Tang S. Association between Personal Abiotic Airborne Exposures and Body Composition Changes among Healthy Adults (60–69 Years Old): A Combined Exposome-Wide and Lipidome Mediation Approach from the China BAPE Study. Environmental Health Perspectives 2024, 132: 077005. PMID: 39028628, PMCID: PMC11259245, DOI: 10.1289/ehp13865.Peer-Reviewed Original ResearchConceptsFat mass indicatorsHealthy older adultsBayesian kernel machine regressionVisceral fat areaOlder adultsPercent body fatBody compositionBody fat massExposome-wide association studyPrevention of chronic diseasesAir pollution exposureBody composition indicatorsMediation analysisInBody 770 deviceHealthy adultsAssociated with increased body fat massBody composition changesKernel machine regressionBayesian kernel machine regression modelsChronic diseasesPollution exposureBody fatAssociation studiesAdverse health effectsFat areaAccuracy of self-reported distance to nearest unconventional oil and gas well in Pennsylvania, Ohio, and West Virginia residents and implications for exposure assessment
Clark C, Casey J, Bell M, Plata D, Saiers J, Deziel N. Accuracy of self-reported distance to nearest unconventional oil and gas well in Pennsylvania, Ohio, and West Virginia residents and implications for exposure assessment. Journal Of Exposure Science & Environmental Epidemiology 2024, 34: 512-517. PMID: 38448680, DOI: 10.1038/s41370-023-00637-8.Peer-Reviewed Original ResearchSelf-reported distanceWest Virginia residentsAssociated with adverse health outcomesVirginia residentsAdverse health outcomesExposure to environmental hazardsCohen's weighted kappaYears of educationSelf-reported dataHealth outcomesWest VirginiansSelf-report measuresIndicators of awarenessWeighted kappaSelf-reportDemographic characteristicsEducational attainmentAdverse health effectsSelf-reported metricsEnvironmental exposuresDistance categoriesHealth effectsResidentsExposure assessmentRisk
2023
Long-term exposure to ambient air pollution and inflammatory response in the KORA study
Vogli M, Peters A, Wolf K, Thorand B, Herder C, Koenig W, Cyrys J, Maestri E, Marmiroli N, Karrasch S, Zhang S, Pickford R. Long-term exposure to ambient air pollution and inflammatory response in the KORA study. The Science Of The Total Environment 2023, 912: 169416. PMID: 38123091, DOI: 10.1016/j.scitotenv.2023.169416.Peer-Reviewed Original ResearchConceptsLong-term exposure to ambient air pollutionLong-term exposure to air pollutionExposure to ambient air pollutionExposure to air pollutionAmbient air pollutionAir pollutionUltrafine particlesParticulate matterIncrease of PM<sLand-use regression modelsAnnual mean concentrationsAtmospheric particulate matterAssociated with increased IL-6Adverse health effectsAssociated with higher concentrationsLand-useMean concentrationsParticipant's home addressPollutionLong-term studiesHealth effectsHigher concentrationsNitrogen oxidesMultiple linear regressionHome addressEffects of Short- And Medium-Term Exposures to Lower Air Temperature on 71 Novel Biomarkers of Subclinical Inflammation: Results from the KORA F4 Study
Ni W, Breitner S, Nikolaou N, Wolf K, Zhang S, Peters A, Herder C, Schneider A. Effects of Short- And Medium-Term Exposures to Lower Air Temperature on 71 Novel Biomarkers of Subclinical Inflammation: Results from the KORA F4 Study. Environmental Science And Technology 2023, 57: 12210-12221. PMID: 37552838, PMCID: PMC10448716, DOI: 10.1021/acs.est.3c00302.Peer-Reviewed Original ResearchConceptsKORA F4 studyBiomarkers of subclinical inflammationHigher risk of chronic diseasesF4 studyLevels of air pollutionLow air temperatureRisk of chronic diseasesPopulation-based KORA F4 studyCross-sectional analysisSubclinical inflammationAdverse health effectsCumulative lagAssociated with higher levelsAir pollutionAir temperatureChronic diseasesNeurotrophin-3Older participantsInterleukin-6Additive modelMedium-term effectsProximity extension assay technologyHealth effectsCardiovascular diseaseHigh riskHarmful algal bloom aerosols and human health
Lim C, Yoon J, Reynolds K, Gerald L, Ault A, Heo S, Bell M. Harmful algal bloom aerosols and human health. EBioMedicine 2023, 93: 104604. PMID: 37164781, PMCID: PMC10363441, DOI: 10.1016/j.ebiom.2023.104604.Peer-Reviewed Original ResearchConceptsHealth effectsPublic health burdenDose-response relationshipPopulation-level exposureExposure assessment methodsAdverse health effectsRespiratory outcomesHealth burdenEpidemiological designHealth databasesLong-term exposureHealth outcomesEvidence gapsConcurrent exposureThreshold doseMixture of toxinsVulnerable subpopulationsAdditional studiesNumber of studiesSubsequent exposureExposureOutcomesHuman healthToxin concentrationHealth
2022
Emerging and Legacy Per- and Polyfluoroalkyl Substances in an Elderly Population in Jinan, China: The Exposure Level, Short-Term Variation, and Intake Assessment
Jia X, Jin Q, Fang J, Shi Y, Hou M, Dong H, Liu Y, Deng F, Zhou Y, Pollitt K, Tang S, Shi X, Cai Y. Emerging and Legacy Per- and Polyfluoroalkyl Substances in an Elderly Population in Jinan, China: The Exposure Level, Short-Term Variation, and Intake Assessment. Environmental Science And Technology 2022, 56: 7905-7916. PMID: 35584234, DOI: 10.1021/acs.est.2c00381.Peer-Reviewed Original ResearchConceptsElderly adultsHealthy elderly adultsBw/dayHuman exposureAdverse health effectsMedian intakeIntake assessmentElderly populationMonth assessment periodDietary ingestionHealth effectsInternal exposureWhole bloodPerfluorooctanoic acidExposure levelsImportant exposure pathwayExposure assessmentAssessment periodConsecutive monthsRegression analysisPolyfluoroalkyl substancesPerfluorooctanesulfonic acidCl-PFESAExposureAdultsAssociations between short-term ambient ozone exposure and cause-specific mortality in rural and urban areas of Jiangsu, China
Lin C, Ma Y, Liu R, Shao Y, Ma Z, Zhou L, Jing Y, Bell ML, Chen K. Associations between short-term ambient ozone exposure and cause-specific mortality in rural and urban areas of Jiangsu, China. Environmental Research 2022, 211: 113098. PMID: 35288156, DOI: 10.1016/j.envres.2022.113098.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseAmbient ozone exposureHealth effectsObstructive pulmonary diseaseIschemic heart diseaseRisk of mortalityCause-specific mortalityOzone exposureShort-term ozone exposureRandom-effects modelingAcute health effectsDaily nonaccidental mortalityAdverse health effectsPulmonary diseaseHeart diseaseNonaccidental mortalityEffect estimatesMortalityRural areasRural groupDiseaseExposureRural residentsCounty-specific effectsNational Population CensusRelationships between short-term ambient temperature exposure and kidney disease hospitalizations in the warm season in Vietnam: A case-crossover study
Chu L, Phung D, Crowley S, Dubrow R. Relationships between short-term ambient temperature exposure and kidney disease hospitalizations in the warm season in Vietnam: A case-crossover study. Environmental Research 2022, 209: 112776. PMID: 35074348, DOI: 10.1016/j.envres.2022.112776.Peer-Reviewed Original ResearchConceptsChronic kidney diseaseRisk of hospitalizationTubulo-interstitial diseaseKidney diseaseHospital admissionIndependent associationGlomerular diseaseDisease subtypesAmbient temperature exposureProvince-level hospitalsKidney disease outcomesCase-crossover studyExposure time windowsSingle-day lagsCase-crossover designAdverse health effectsAdditional independent associationsOdds ratioDisease outcomeHospitalizationAdmission dataConvincing associationCumulative associationDiseaseEpidemiologic research
2021
Health impacts of a randomized biomass cookstove intervention in northern Ghana
Abdo M, Kanyomse E, Alirigia R, Coffey E, Piedrahita R, Diaz-Sanchez D, Hagar Y, Naumenko D, Wiedinmyer C, Hannigan M, Oduro A, Dickinson K. Health impacts of a randomized biomass cookstove intervention in northern Ghana. BMC Public Health 2021, 21: 2211. PMID: 34863138, PMCID: PMC8642932, DOI: 10.1186/s12889-021-12164-y.Peer-Reviewed Original ResearchConceptsHealth outcomesSelf-reported health symptomsSelf-reported health outcomesTRIAL REGISTRATION NUMBERC-reactive proteinSerum amyloid ADate of registrationChi-square testSelf-reported healthAdverse health effectsDried Blood SpotsLack of evidenceSystemic inflammationInflammation biomarkersAmyloid AIntervention groupRegistration numberControl groupIntervention studiesHealth symptomsBlood spotsCookstove interventionAnthropometric dataAnthropometry variablesOxidative stressThe exposome in practice: an exploratory panel study of biomarkers of air pollutant exposure in Chinese people aged 60–69 years (China BAPE Study)
Tang S, Li T, Fang J, Chen R, Cha Y, Wang Y, Zhu M, Zhang Y, Chen Y, Du Y, Yu T, Thompson DC, Godri Pollitt KJ, Vasiliou V, Ji JS, Kan H, Zhang JJ, Shi X. The exposome in practice: an exploratory panel study of biomarkers of air pollutant exposure in Chinese people aged 60–69 years (China BAPE Study). Environment International 2021, 157: 106866. PMID: 34525388, DOI: 10.1016/j.envint.2021.106866.Peer-Reviewed Original ResearchConceptsAir pollutant exposurePotential adverse clinical outcomesPollutant exposureExploratory panel studyAdverse clinical outcomesHealthy elderly subjectsAdverse health outcomesAirborne pollutant exposureAir pollution exposureAdverse health effectsClinical outcomesModifiable factorsElderly subjectsHealthy residentsNovel biomarkersEndogenous exposureExogenous exposureHealth outcomesPotential biomarkersAirborne exposurePollution exposureSuboptimal assessmentAdverse health impactsAssociated biomarkersComprehensive biomarkerExposure to organophosphate esters in elderly people: Relationships of OPE body burdens with indoor air and dust concentrations and food consumption
Hou M, Fang J, Shi Y, Tang S, Dong H, Liu Y, Deng F, Giesy JP, Godri Pollitt KJ, Cai Y, Shi X. Exposure to organophosphate esters in elderly people: Relationships of OPE body burdens with indoor air and dust concentrations and food consumption. Environment International 2021, 157: 106803. PMID: 34365320, DOI: 10.1016/j.envint.2021.106803.Peer-Reviewed Original ResearchConceptsElderly peopleHealth effectsWhole bloodFood frequency questionnaireHealthy elderly peopleHigh blood concentrationsBw/dayDaily total intakeAdverse health effectsHigher consumption frequencyTnBP exposureFrequency questionnaireIndoor dustPotential health effectsUrinary levelsBlood concentrationsDietary exposure pathwaysElderly populationOPE exposureExcretory capacityTotal intakeExposure pathwaysSuitable biomarkersBloodConsumption frequencyUse of Untargeted Metabolomics to Explore the Air Pollution-Related Disease Continuum
Jin L, Godri Pollitt KJ, Liew Z, Rosen Vollmar AK, Vasiliou V, Johnson CH, Zhang Y. Use of Untargeted Metabolomics to Explore the Air Pollution-Related Disease Continuum. Current Environmental Health Reports 2021, 8: 7-22. PMID: 33420964, DOI: 10.1007/s40572-020-00298-x.Peer-Reviewed Original ResearchConceptsAir pollutant exposureAdverse health effectsSpecific adverse health effectsOxidative stressHealth effectsPerturbation of metabolitesAir pollution exposureUntargeted metabolomicsPollutant exposureSteroid metabolic pathwaysPregnant womenInflammatory responseDisease continuumReviewThe purposeHealth outcomesLarger sample sizeMetabolic pathwaysDisease statusPollution exposureIdentified metabolitesMetabolic perturbationsMetabolic changesSummaryOur reviewAir pollution componentsMetabolomic analysis
2020
Clinical, Epidemiological and Experimental Approaches to Assess Adverse Health Outcomes of Indoor Biomass Smoke Exposure: Conclusions from An Indo-Swedish Workshop in Mysuru, January 2020
Anand M, Larsson K, Johanson G, Phuleria HC, Ravindra PV, Ernstgård L, Mabalirajan U, Krishna M, Palmberg L, Pollitt KJG, Upadhyay S, Ganguly K. Clinical, Epidemiological and Experimental Approaches to Assess Adverse Health Outcomes of Indoor Biomass Smoke Exposure: Conclusions from An Indo-Swedish Workshop in Mysuru, January 2020. Toxics 2020, 8: 68. PMID: 32899560, PMCID: PMC7560295, DOI: 10.3390/toxics8030068.Peer-Reviewed Original ResearchAdverse health effectsHealth effectsBiomass smoke exposureAdverse health outcomesPotential protective mechanismDeterminants of healthSmoke exposureEpidemiological field studiesHealth outcomesAdult cohortDietary exposureVivo modelProtective mechanismPersonalized exposure assessmentExposure assessmentStudy objectiveNew screening methodExposureMysuruMulti-disciplinary approachFuture studiesOutcomesSpecific aimScreening methodPlausible strategyMolecular Profiling for Predictors of Radiosensitivity in Patients with Breast or Head-and-Neck Cancer
Drobin K, Marczyk M, Halle M, Danielsson D, Papiez A, Sangsuwan T, Bendes A, Hong MG, Qundos U, Harms-Ringdahl M, Wersäll P, Polanska J, Schwenk JM, Haghdoost S. Molecular Profiling for Predictors of Radiosensitivity in Patients with Breast or Head-and-Neck Cancer. Cancers 2020, 12: 753. PMID: 32235817, PMCID: PMC7140105, DOI: 10.3390/cancers12030753.Peer-Reviewed Original ResearchSingle nucleotide polymorphismsCancer patientsRadiosensitive patientsProteomic dataDNA repairSNP variantsRadiation-induced toxicityNeck cancer patientsLong-term survivalPredictors of radiosensitivityNucleotide polymorphismsProteinAdverse health effectsPlasma proteomicsGrowth capacityNeck cancerPredictive proteinsBreast cancerImmune responsePatient radiosensitivityPatientsStudy setDNA genotypingMolecular profilingNormal tissuesGlobal reach of ageism on older persons’ health: A systematic review
Chang ES, Kannoth S, Levy S, Wang SY, Lee JE, Levy BR. Global reach of ageism on older persons’ health: A systematic review. PLOS ONE 2020, 15: e0220857. PMID: 31940338, PMCID: PMC6961830, DOI: 10.1371/journal.pone.0220857.Peer-Reviewed Original ResearchConceptsSystematic reviewOlder personsHealth outcomesOlder persons' healthPrevious systematic reviewWorse health outcomesComprehensive systematic reviewAdverse health effectsRace/ethnicityStudy protocolStudy qualityEvidence of ageismGreater prevalenceHealth consequencesLiterature searchSystematic searchHealth effectsHealth domainsStandardized toolsPerson's healthPrevalenceHealthFull reviewOutcomesSignificant findings
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