INFORMATION FOR
News
Q&A with Pei Hui, PhD, MD, a surgical pathologist, in recognition of Gynecologic Cancer Awareness Month.
The dataset has been developed for the pathology reporting of resection specimens for primary uterine gestational trophoblastic neoplasia which includes invasive hydatidiform mole of either complete or partial type, gestational choriocarcinoma, placental site trophoblastic tumour and epithelioid trophoblastic tumour. The dataset should be used primarily for hysterectomy specimens. This dataset may also be used for rare myomectomy specimens but not all elements will be applicable. The dataset is not intended to be used for extrauterine primary lesions. Non-gestational trophoblastic tumours (germ cell or somatic origin) and metastatic tumours are excluded from this dataset.
In this episode of MODPATH CHAT, our guests Dr. Natalia Buza and Dr. Pei Hui from the department of Pathology at Yale University share their approach to the application of DNA genotyping to the diagnosis and prognostication of Hydatidiform moles and Gestational trophoblastic tumors. Genotyping is now the gold standard in the confirmation and subtyping of sporadic hydatidiform moles. DNA genotyping is critical to the separation of gestational trophoblastic neoplasia from non-gestational counterparts/mimics of either germ cell or somatic origin.