A Strange Rash Had Doctors Stumped. Was It an Insect Bite?
The 73-year-old man looked up at the clear summer sky — the morning was nearly gone. He had finished mowing the main part of his lawn and was trimming the edges near the shrubbery with the weed wacker. He wanted to finish before the sun and heat made the work too hard. Suddenly he felt a sharp sting on the lower part of his shin. He glanced down at his bare leg. Nothing there. He still had the hedges to trim, so he kept working. He quickly finished the needed pruning, then moved on to the inside tasks he had planned.Source: The New York Times Magazine
Yale Researchers Take Stem Cells One Step Closer to Replacing Parathyroid Gland Function
Yale investigators have developed a multistep process that models the biological instructions to create parathyroid gland cells from pluripotent stem cells, a significant milestone along the path toward helping people who lack the hormones released by parathyroid glands.
Quick and affordable saliva-based COVID-19 test developed by Yale scientists receives FDA Emergency Use Authorization
A saliva-based laboratory diagnostic test developed by researchers at the Yale School of Public Health to determine whether someone is infected with the novel coronavirus has been granted an emergency use authorization by the U.S. Food and Drug Administration (FDA).Source: Yale News
An Innovative Treatment Approach for DIPG: CureSearch for Children’s Cancer Partners with SebastianStrong Foundation to Fund Promising New Research
CureSearch for Children’s Cancer, in partnership with the SebastianStrong Foundation, has awarded a $225,000 Young Investigator grant to Yale Cancer Center’s Dr. Ranjithmenon Muraleedharan, who will develop a new treatment approach for diffuse intrinsic pontine glioma (DIPG) – a devastating brain cancer with a 5-year survival rate of less than 1%. The 3-year project is funded by SebastianStrong Foundation’s Discovery Science Award.Source: CureSearch for Children's Cancer
$15M NIDA Grant Awarded to Serena Spudich, Mark Gerstein, and Yuval Kluger
Principal Investigators Serena Spudich, MD, MA (Neurology), Mark Gerstein, PhD (Molecular Biophysics and Biochemistry), and Yuval Kluger, PhD (Pathology) were recently awarded a $15 million grant from the National Institute on Drug Abuse (NIDA) to establish a Data Center to coordinate, analyze, and make accessible single-cell and other molecular data sets generated by Single-Cell Opioid Responses in the Context of HIV (SCORCH) and other NIDA-funded HIV and substance use disorder projects.
A Call for More COVID-19 Vaccine Funding, and Praise for Yale's Achievements
On July 24, United States Senator Richard Blumenthal (D-CT) highlighted research conducted at Yale School of Medicine and urged his Senate colleagues to approve more federal funding for development and distribution of vaccines to halt the COVID-19 pandemic.
Yale Pathology Professor Receives NIH Award for Breakthrough Cancer Research
The award — granted to just 5% of NIH-funded investigators —ensures that Kurt Schalper’s research will be funded for the next seven years. It supports his groundbreaking work identifying novel pathways for cancer immunotherapy which can be used to optimally select and treat patients with non-small cell lung cancer.Source: YaleNews
Covid-19 Blood Clotting Cause Identified in Study Led by Yale Cancer Center Researchers
New findings led by Yale Cancer Center researchers and experts across several medical specialties at Yale identify a leading mechanism behind the pathophysiology of Covid-19 and pinpoint a biological marker for the mechanism that may aid in treating these patients.
Yale Cancer Center Study Validates Combination Therapy for Aggressive Endometrial Cancer
Yale Cancer Center (YCC) scientists have found that combining the targeted drug trastuzumab with chemotherapy significantly improves survival rates for women with a rare, aggressive form of endometrial cancer. These results may help to change the standard of care worldwide for the disease. The findings are published today in the journal Clinical Cancer Research.
Blocking a ‘Jamming Signal’ Can Unleash Immune System to Fight Tumors
Yale researchers have discovered a “jamming signal” that blocks a powerful immune system stimulant called interleukin-18 (IL-18) from reaching tumors, including in cancers that are resistant to conventional immunotherapy treatments, they report June 24 in the journal Nature.
Yale Cancer Center Tumor Study Shows Triple-Negative Breast Cancer Has Different Biology in African Americans
In a new study of tumor microenvironment led by Yale Cancer Center, researchers showed that triple-negative breast cancer which has a worse overall outcome in African American compared to Caucasian patients actually has a different Tumor Microenvironment in the two mentioned groups.
Gift from Ludwig Family Foundation Funds Urgent COVID Research by School of Medicine Scientists
The donation will fund the laboratories of at least six scientists on the Yale School of Medicine faculty, for work on vaccine development to prevent future outbreaks as well as treatments for people who are already infected.