A Strange Rash Had Doctors Stumped. Was It an Insect Bite?
The 73-year-old man looked up at the clear summer sky — the morning was nearly gone. He had finished mowing the main part of his lawn and was trimming the edges near the shrubbery with the weed wacker. He wanted to finish before the sun and heat made the work too hard. Suddenly he felt a sharp sting on the lower part of his shin. He glanced down at his bare leg. Nothing there. He still had the hedges to trim, so he kept working. He quickly finished the needed pruning, then moved on to the inside tasks he had planned.Source: The New York Times Magazine
How do hair follicles grow? A Yale-led study untangles the science
An outstanding question in dermatology that researchers have studied for decades is: How do hair follicles emerge from a sea of seemingly uniform skin cells during embryonic development? New research findings from a Yale-led team offer answers to that question, which may lead to strategies for regenerating lost hair follicles in adults.
Yale experts treat severe, disfiguring sarcoidosis with novel therapy
An all-Yale team of researchers successfully treated a patient with disfiguring sarcoidosis, a disease that can affect multiple organs, with a drug approved for rheumatoid arthritis. Successful treatment of two other patients with similarly severe disease suggests an effective treatment for an incurable, sometimes life-threatening illness is within reach.
Two Yale School of Medicine MD-PhD Students Receive Prestigious Soros Fellowship for New Americans
Jonathan Marques and Diana Yanez, both currently in the School of Medicine’s (YSM) MD-PhD program, have been selected as 2018 Soros Fellows. Marquez and Yanez are among 30 recipients of the Paul & Daisy Soros Fellowships for New Americans. Fellows, all of whom are children of immigrants to the Unites States, Deferred Action for Childhood Arrival recipients, green card holders, or naturalized citizens, were selected from a pool of 1,766 applicants for their potential to make significant contributions to United States society, culture, or their academic fields, and for their commitment to the United States’ fundamental principles and ideals.
Skin Health: New Insights from a Rare Disease
Skin is the largest organ in the human body, yet we often take for granted all of the wonderful things that it does to keep us healthy. That’s not the case for people who suffer from a group of rare, scale-forming skin disorders known as ichthyoses.Source: NIH Directors Blog
Yale Cancer Center researchers win Sokoloff Family-Melanoma Research Alliance team science award
A new approach to understanding why T-cells are often too weak to fight and destroy tumor cells has earned Yale Cancer Center researchers team science award from the Sokoloff Family-Melanoma Research Alliance (MRA).
Yale-led study zeroes in on mutation linked to zits
Little is known about the genetic causes of pimples and other forms of acne that plague most teenagers. In a new study, a team of Yale researchers identified a genetic mutation responsible for the defects that give rise to mild and severe acne. Their finding might point to new targets for acne treatment.
Yale study identifies ‘major player’ in skin cancer genes
A multidisciplinary team at Yale, led by Yale Cancer Center members, has defined a subgroup of genetic mutations that are present in a significant number of melanoma skin cancer cases. Their findings shed light on an important mutation in this deadly disease, and may lead to more targeted anti-cancer therapies.
Mutation Mystery: A Clinician Seeks Answers to Improve Skin Cancer Treatment for Women
Dr. Christine Ko has launched a study to see if a mutated gene can serve as a biological marker to predict the growth rate and recurrence of squamous cell carcinoma, a type of tumor of the thin outer layer of skin that affects about 700,000 Americans each year.
A tiny RNA with a big role in melanoma
A Yale-led study has identified a key mechanism in the regulation of gene expression that promotes the proliferation of melanoma cells. The finding opens a possible avenue for development of treatments that target this mechanism. The study appears online Feb. 18 in the journal eLife.
How much sunlight you really need to get enough vitamin D
The sun is our most common source of vitamin D since it's rarely found in foods. In fact, when exposed to ultraviolet B (UVB) rays, our skin produces vitamin D naturally. Yet, about 35% of adults in America have a vitamin D deficiency. Important: Adults need about 15 micrograms of vitamin D daily to meet nutrient requirements. And that's a problem since vitamin D is important for strengthening and maintaining bones, supporting a healthy immune system, and breaking down glucose in the body, says David J. Leffell, MD, chief of Yale Medicine Dermatologic Surgery and professor of dermatology at Yale School of Medicine. Here's how to make sure you're getting enough of it from the sun.Source: Insider
How often should I shower?
So you want to know how often you should be showering. We have answers. Now, you may not like all our answers, but we’re not here to help you win an argument about personal hygiene or determine whether the latest lightly rinsed celebrity is being weird or not. We’re here to give you the facts you need to stay clean the best you can. Come on, how often do I need to shower? There’s not one right answer, but a range of right answers. Generally, people shower somewhere between every other day and twice a day, depending on their personal preference and how their skin reacts to getting hosed down, says Jeffrey Cohen, a dermatologist and assistant professor at the Yale School of Medicine. So if you’re in that range, you’re doin’ fine.Source: Popular Science
Psoriasis Causes, Plus 7 Things That Can Cause Symptom Flare-Ups, According to Dermatologists
A psoriasis flare-up can be uncomfortable, both physically and emotionally—and all the more frustrating when it strikes at an inopportune time. While the cause of psoriasis isn't exactly clear, there's some evidence that your immune system and the genes you inherit play a role, says National Psoriasis Foundation (NPF). But those factors don't tell the whole story. Understanding what's triggering your psoriasis flare-ups can help you gain better control, says the American Academy of Dermatology (AAD). We asked dermatologists to unpack the complexities of how those itchy, painful patches come to be. Here's what to know about the causes and triggers of psoriasis.Source: Health
7 ways to get rid of and prevent forehead wrinkles, according to dermatologists
Forehead wrinkles and fine lines are a normal and unavoidable part of aging. "As we age, we lose collagen, and this can also contribute to fine lines and wrinkles becoming more apparent," says Marisa Garshick, MD, FAAD, a dermatologist at MDCS Dermatology. Medical term: Collagen is a naturally occurring protein that keeps the skin firm. Although aging reduces collagen production in the body, environmental factors like sun exposure and cigarette smoke can also damage collagen fibers in the body, which accelerates the aging process and causes wrinkles to develop. While forehead wrinkles shouldn't be something you're ashamed of, if you want to reduce their appearance, there are plenty of ways to do so.Source: Insider
How to differentiate harmless sunspots from skin cancer
Sunspots are flat, dark spots that appear on parts of your skin that you frequently expose to the sun, such as your face, hands, arms, shoulders, and feet. While anyone can develop these spots, they are particularly common in people with light skin over the age of 40, especially those who spend a lot of time in the sun. Genetics also play a role, so having a family history of sunspots can make you more likely to get them. Note: Sunspots are also known as age spots, solar lentigines, and liver spots although they don't have anything to do with liver function. Sunspots are permanent marks that are harmless, so you don't need to remove them for health reasons. However, if you don't like their appearance, there are steps you can take to lighten them. Here are some tips on how to prevent sunspots and reduce their appearance, as well as how to differentiate a sunspot from something more serious like skin cancer.Source: Insider
What Does Hypoallergenic Really Mean?
An allergy is your immune system's response to something that doesn't bother a lot of other people. It's why your best friend can cuddle a new kitten without a problem while you sneeze your way out the door. a person talking on a cell phone© Provided by Best Health "Allergies are immune reactions that show a person is hypersensitive, usually on an acute basis, to certain substances," explains Christine Ko, MD, a Yale Medicine dermatologist, dermatopathologist, and professor at Yale School of Medicine in New Haven, Connecticut.Source: MSN
How to spot poison oak and the rash it causes
Poison oak is a shrub that grows on the west coast and southeast region of North America. These poisonous plants have leaves that usually: Grow in groups of three Have rounded or wavy edges Are green Have fuzzy undersides that are usually a lighter color than the top Sometimes, there might be a visible black substance, called urushiol, on the leaves or stems. This is the same compound found in other poisonous plants like poison ivy and is responsible for causing a rash in most people. A rash from poison oak will appear pink, red, or less commonly, black. In more severe cases, you might also see blisters, says Christine Ko, MD, PhD, Yale Medicine dermatologist, dermatopathologist, and professor at Yale School of Medicine. RELATED How to tell if you have a poison oak rash and how to treat it Not everyone will develop a rash from poison oak. It's estimated that about 85% of people are allergic to urushiol and will get a rash on contact, and the rest will not.Source: Insider